Nephrology

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Lupus Nephritis

Precision Medicine for Lupus

Precision Medicine for Lupus

Ongoing studies are now looking at pharmacogenetics when comparing mycophenolate mofitil and cyclophosphamide for treating lupus nephritis.

Nephrology News

Latest Nephrology News

Acute Kidney Injury Platelet Counts Linked to AKI Severity in Pediatric Open-Heart Surgery

Platelet Counts Linked to AKI Severity in Pediatric Open-Heart Surgery

There is a strong association between magnified nadir platelet counts and the severity of AKI.

Secondary Hyperparathyroidism Why SHPT Requires Management

Why SHPT Requires Management

Clinical practice guidelines recommend that PTH levels be kept within specific ranges to prevent adverse outcomes.

Hypertension Millions of US Adults May Have Masked Hypertension

Millions of US Adults May Have Masked Hypertension

An estimated 12.3% of Americans over the age of 21 have masked hypertension.

Diabetes Biomarkers, Clinical Variables Predict Renal Function Loss in T2DM

Biomarkers, Clinical Variables Predict Renal Function Loss in T2DM

A small set of serum protein biomarkers combined with clinical variables, enhances the prediction of renal function loss over a wide range of baseline eGFR values.

Secondary Hyperparathyroidism FGF-23 Indirectly Associated With Vascular Calcification

FGF-23 Indirectly Associated With Vascular Calcification

In a small study, 50% of non-diabetic hemodialysis patients with elevated FGF-23 showed correlations with calcification in the abdominal aorta.

Diabetes Sitagliptin OK for Older Type 2 Diabetes Patients With CVD

Sitagliptin OK for Older Type 2 Diabetes Patients With CVD

Sitagliptin did not significantly impact the primary composite, death, heart failure hospitalization, severe hypoglycemia, rates of acute pancreatitis and pancreatic cancer, or serious adverse events.

Secondary Hyperparathyroidism Hungry Bone Syndrome Risk Factors ID'd in Total PTx Patients

Hungry Bone Syndrome Risk Factors ID'd in Total PTx Patients

The syndrome is more likely to develop in younger patients and those with higher preoperative ALP levels and lower preoperative calcium levels.

Nephrology Copeptin Predicts IgA Nephropathy Outcomes

Copeptin Predicts IgA Nephropathy Outcomes

Copeptin, a surrogate marker for arginine vasopressin (AVP), showed prognostic value of established risk markers.

Diabetes Metabolites Linked to Faster Renal Decline, Failure in Type 1 Diabetes

Metabolites Linked to Faster Renal Decline, Failure in Type 1 Diabetes

Serum levels of 7 modified metabolites were associated with renal function decline and time to ESRD.

Hemodialysis Frequent Hemodialysis Improves Health-Related QoL

Frequent Hemodialysis Improves Health-Related QoL

Patients feel better and recovery times are shorter with 6 hemodialysis sessions per week rather than 3, researchers report.

Hypertension Higher Systolic BP Target Recommended for Older Patients

Higher Systolic BP Target Recommended for Older Patients

New guidelines suggest aiming for a systolic pressure less than 150 mm Hg in hypertensive individuals aged 60 or older.

Hypertension Beta-Blockers May Reduce Death Risk in HFrEF, A-Fib

Beta-Blockers May Reduce Death Risk in HFrEF, A-Fib

With respect to mortality and hospitalizations, there were no significant interactions for β-blockers and pattern or burden of AF.

Diabetes Fenofibrate May Reduce CVD in Statin-Treated T2DM Patients

Fenofibrate May Reduce CVD in Statin-Treated T2DM Patients

The continued observation of heterogeneity of treatment response by baseline lipids suggests that fenofibrate therapy may reduce CVD in patients with diabetes.

Anemia Iron-Based Phosphate Binder Safely Treats Anemia in CKD Patients

Iron-Based Phosphate Binder Safely Treats Anemia in CKD Patients

In a study 52.1% of patients receiving ferric citrate attained a 1.0 g/dL or greater increase in hemoglobin compared with just 19.1% receiving placebo.

Nephrology ESRD Risk Factors in IgAN Patients Identified

ESRD Risk Factors in IgAN Patients Identified

Predictors of renal failure within 10 years include Oxford M1 disease and low eGFR at biopsy.

Hypertension Hypertension, Prehypertension Increasing Worldwide

Hypertension, Prehypertension Increasing Worldwide

United States, China, India, Indonesia, and Russia accounted for more than 50% of elevated or high blood pressure cases.

Diabetes Hepatitis B More Prevalent in Type 2 Diabetes Patients

Hepatitis B More Prevalent in Type 2 Diabetes Patients

Patients with type 2 diabetes had higher prevalence of CHB than the controls in the overall population.

Diabetes ESRD From Diabetes Declining in Native Americans

ESRD From Diabetes Declining in Native Americans

The Indian Health Service has made progress by applying population health and team-based approaches to diabetes and kidney care.

Nephrology Valerian Root Herbal Remedy Linked to Life-Threatening Hyponatremia

Valerian Root Herbal Remedy Linked to Life-Threatening Hyponatremia

The patient had a brief period of confusion and altered behavior followed by a collapse and seizure caused by root supplements.

Secondary Hyperparathyroidism Etelcalcetide Reduces PTH Levels in Moderate to Severe SHPT

Etelcalcetide Reduces PTH Levels in Moderate to Severe SHPT

Benefits over placebo were demonstrated in 2 trials involving hemodialysis patients with moderate to severe secondary hyperparathyroidism.

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