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Acute Kidney Injury

AKI Soon After Nephrectomy Rare, Study Finds

May 19, 2012

Acute kidney injury (AKI) rarely occurs in the immediate postoperative period following nephrectomy, according to a study presented at the American Urological Association 2012 annual meeting.
 

Fluid Overload in Burn Patients Affects Survival

May 13, 2012

NATIONAL HARBOR, Md.—Fluid overload in adult burn patients is associated with increased mortality, data presented at the National Kidney Foundation 2012 Spring Clinical Meetings suggest.
 

CKD Elevates Risk of Post-Op AKI

May 12, 2012

NATIONAL HARBOR, Md.—Patients with chronic kidney disease (CKD) before undergoing surgical procedures are at increased risk of acute kidney injury (AKI) post-operatively, researchers reported at the National Kidney Foundation Spring Clinical Meetings.
 

Acute Renal Failure

Summer Heat Increases Risk of Renal Problems

April 13, 2012

Higher summer temperatures increase the likelihood of being hospitalized for acute renal failure (ARF), according to an analysis of data collected in New York State.
 

Based on your own experience, do you think higher temperatures increase the risk of urinary tract problems?

April 12, 2012

A recently published study found that increasing mean temperature was associated with urinary disorders.
 

ARF Need Not Prevent Kidney Donation

March 12, 2012

The use of kidneys from deceased donors with acute renal failure (ARF) can be safe and produce good renal function up to one year after transplantation, new research has confirmed.
 

Anemia

Peginesatide Requirements Do Not Differ By Race

May 13, 2012

NATIONAL HARBOR, Md.—Black hemodialysis (HD) patients with anemia require relatively more epoetin than their non-black counterparts to achieve similar hemoglobin (Hb) levels, but blacks and non-blacks required similar peginesatide doses, according to findings presented at the National Kidney Foundation 2012 Spring Clinical Meetings.
 

Rapid Anemia Management May Reduce Hospital Readmission Rates

May 12, 2012

NATIONAL HARBOR, Md.—Rapid anemia management (RAM) for patients with end-stage renal disease within seven days of hospital discharge decreases their rate of readmission, according to findings presented at the National Kidney Foundation 2012 Spring Clinical Meetings.
 

Complete Anemia Correction Better for Renal Transplant Patients

April 23, 2012

Completely correcting anemia in kidney transplant recipients may preserve kidney function better than partially correcting anemia.
 

Chronic Kidney Disease

No Increased Fracture Rate with Decreasing eGFR

May 16, 2012

ST. JOHN'S, NEWFOUNDLAND—A new analysis suggests there is no association between lower estimated glomerular filtration rate (eGFR) and non-traumatic hip-, vertebral- or wrist-fracture rates. This contradicts earlier studies showing a four-fold higher fracture rate with end-stage renal disease (ESRD).
 

Novel Formulation Corrects Vitamin D, Lowers iPTH

May 13, 2012

NATIONAL HARBOR, Md.—An investigational treatment safely and effectively lowers elevated plasma intact parathyroid hormone (iPTH) levels in patients with stage 3 or 4 chronic kidney disease and vitamin D deficiency, researchers reported at the National Kidney Foundation 2012 Spring Clinical Meetings.
 

SHPT Linked to Vitamin D Deficiency in CKD Patients

May 12, 2012

NATIONAL HARBOR, Md.—Vitamin D deficiency is strongly associated with secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD), according to data presented at the National Kidney Foundation (NKF) 2012 Spring Clinical Meetings.
 

Contrast Nephropathy

Hyponatremia May Predict Contrast-Induced Nephropathy

July 05, 2011

PRAGUE—Transient hyponatremia may precede development of contrast-induced nephropathy (CIN) in patients undergoing coronary angiography, according to investigators.
 

Drug Offers No CIN Protection

January 11, 2011

CHICAGO—Brazilian researchers report that acetylcysteine should no longer be used to prevent contrast-induced nephropathy (CIN) in patients undergoing coronary and vascular angiography.
 

CIN Prevention Strategies Similarly Effective

June 18, 2010

Researchers find no difference between saline and sodium bicarbonate.
 

Cardiovascular Disease

Heart Failure Linked to Orthostatic Hypotension

April 10, 2012

Orthostatic hypotension predicts incident heart failure among middle-aged adults, especially those aged 45-55 years old, researchers reported online ahead of print in Hypertension.
 

Nut Consumers Have Lower Health Risks

March 07, 2012

Nut consumption is associated with a decreased prevalence of certain risk factors for cardiovascular disease, type 2 diabetes, and metabolic syndrome, according to a recent study.
 

Newer Antihypertensive Agents May Be No Better than Diuretics

January 20, 2012

Calcium channel blockers (CCBs) and ACE inhibitors may be no better than diuretics at preventing cardiovascular deaths in patients with hypertension, according to a follow-up study of patients in a seminal antihypertensive trial. In addition, CCBs and ACE inhibitors may increase cardiovascular risks.
 

Diabetes

Metformin plus Insulin Comparable to Insulin Alone in Type 2 Diabetes

April 20, 2012

More data needed to determine whether combined use of oral therapy and insulin adds benefit
 

SPK Transplants May Offer No Advantage for Type 2 Diabetes

April 17, 2012

Simultaneous pancreas-kidney (SPK) transplantation offers no patient or survival advantage over deceased-donor kidney transplantation alone (DDKA) for selected patients with type 2 diabetes, new findings suggest.
 

Normoalbuminuria Does Not Always Mean Normal Kidney Function

April 16, 2012

Many patients with diabetes have significant renal dysfunction despite having normo- or microalbuminuria, according to researchers.
 

Diabetic Nephropathy

ESRD More Likely than Death for Patients with Diabetic Nephropathy

December 07, 2011

Patients with type 2 diabetic nephropathy are more likely to progress to end-stage renal disease (ESRD) than die, according to investigators.
 

Pirfenidone May Help Treat Diabetic Nephropathy

May 13, 2011

An anti-fibrotic and anti-inflammatory drug called pirfenidone may help treat diabetic nephropathy, according to a new randomized, double-blind study.
 

New Agent May Prevent Diabetic Nephropathy

April 14, 2011

Utah researchers report success with a new agent for preventing diabetic nephropathy. The agent is called atrasentan and it is a highly selective endothelin-A receptor (ETAR) agonist.
 

Focal Segmental Glomerulosclerosis

Steroids May Harm Athletes' Kidneys

March 02, 2010

Serious renal damage is a possible consequence of long-term abuse of anabolic steroids, data show .
 

Mycophenolate Mofetil Works As Well As Standard Therapy

July 22, 2008

Six months of mycophenolate mofetil (MMF) treatment is as effective in the short term as conventional therapy for primary treatment of membranous nephropathy (MN) and focal segmental glomerulosclerosis (FSGS), a pilot study in India found.
 

MMF Similar to Conventional Therapies for MN, FSGS

January 01, 2008

A six-month course of treatment with mycophenolate mofetil (MMF) is as effective as conventional therapies for treating membranous nephropathy (MN) and focal segmental glomerulosclerosis (FSGS), according to a pilot study conducted in India.
 

Hemodialysis

High, Low PTH Raises Hypercalcemia Risk

May 13, 2012

NATIONAL HARBOR, Md.—Low and high levels of parathyroid hormone (PTH) are associated with hypercalcemia, according to a study of 106,760 hemodialysis patients presented at the National Kidney Foundation 2012 Spring Clinical Meetings suggest.
 

Peginesatide Requirements Do Not Differ By Race

May 13, 2012

NATIONAL HARBOR, Md.—Black hemodialysis (HD) patients with anemia require relatively more epoetin than their non-black counterparts to achieve similar hemoglobin (Hb) levels, but blacks and non-blacks required similar peginesatide doses, according to findings presented at the National Kidney Foundation 2012 Spring Clinical Meetings.
 

Labs May Vary in iPTH Measurements

May 12, 2012

NATIONAL HARBOR, Md.—Laboratories can differ in their measurements of intact parathyroid hormone (iPTH) levels, resulting in varying treatment approaches for hemodialysis (HD) patients depending on the iPTH assay used, researchers reported at the National Kidney Foundation Spring Clinical Meetings.
 

Hyperphosphatemia

Novel Iron-Based Phosphate Binder Effective, Well-Tolerated

May 11, 2012

NATIONAL HARBOR, Md.—An investigational iron-based phosphate binder is effective and well tolerated in hemodialysis (HD) patients with hyperphosphatemia, according to data presented at the National Kidney Foundation 2012 Spring Clinical Meetings.
 

Novel Tool May Help Dialysis Patients with Phosphorus Control

April 30, 2011

LAS VEGAS—A novel interactive Web-based phosphorus education tool may help to improve phosphorus control in dialysis patients, according to a report at the National Kidney Foundation's Spring Clinical Meetings.
 

Hyperphosphatemia and Anemia Risk Factors in Diabetic Nephropathy Patients

April 30, 2011

LAS VEGAS—Albumunuria, proteinuria, lower estimated glomerular filtration rate (eGFR) in patients with diabetic nephropathy are significantly associated with hyperphosphatemia and anemia, researchers reported at the National Kidney Foundation's Spring Clinical Meetings.
 

Hypertension

Study Identifies RCC Risk Factors

May 19, 2012

A history of kidney disease, hypertension, high body mass index (BMI), and smoking are independently associated with an increased risk of renal cell carcinoma (RCC), researchers reported at the American Urological Association 2012 annual meeting.
 

Page Kidney Resulting in New Onset Hypertension

, May 01, 2012

A 55-year-old Caucasian woman initially presented to one of Cleveland Clinic's regional outpatient urology clinics with gross hematuria and an obstructing right ureteral stone.
 

Remoteness May Affect Hypertension Risk

April 23, 2012

Hypertension risk among individuals living in rural areas may depend on the distance of their residence from population centers, according to a study conducted in Japan.
 

Hyperuricemia

BP, Uric Acid Linked in Adolescents

April 09, 2012

Elevated blood pressure is twice as likely in those with a serum uric acid level of 5 mg/dL or higher
 

Part II: Clinical Challenges and Renal Considerations in Managing Gout

By James W. Lohr, MD April 01, 2012

A case study involving a 65-year-old man with chronic kidney disease and acute attacks of pain, swelling, and erythema in the first metatarsophalangeal joint.
 

Renal Cysts More Common in Gout Patients

March 30, 2012

Gout patients have an increased prevalence of simple renal cysts, and these cysts are associated with a decreased likelihood of kidney stone disease, according to Brazilian investigators.
 

Kidney Cancer

Survival Better with Partial Nephrectomy

May 19, 2012

Partial nephrectomy (PN) is associated with better overall survival compared with radical nephrectomy (RN) for patients with early-stage kidney cancer, researchers reported at the American Urological Association 2012 annual meeting.
 

Drug Cleared for Treating Renal Angiomyolipomas

April 27, 2012

The FDA has approved everolimus (Afinitor) for the treatment of renal angiomyolipomas and tuberous sclerosis complex (TSC) in adult kidney tumor patients who do not require immediate surgery.
 

Active Surveillance May Be Okay for Some Men with Metastatic Kidney Cancer

April 27, 2012

Active surveillance may be appropriate for up to 10% of patients with metastatic kidney cancer, according to researchers at the Cleveland Clinic.
 

Kidney Stones

In pediatric renal stone cases for which either shockwave lithotripsy (SWL) or ureteroscopy would be appropriate, which approach do you prefer?

May 04, 2012

Researchers recently published a study showing that the proportion of pediatric kidney stone cases treated with ureteroscopy has increased significantly relative to the use of SWL.
 

Urology Practice Setting Affects Stone Treatment Choice

May 04, 2012

Shock wave lithotripsy use more common among community practices.
 

Page Kidney Resulting in New Onset Hypertension

, May 01, 2012

A 55-year-old Caucasian woman initially presented to one of Cleveland Clinic's regional outpatient urology clinics with gross hematuria and an obstructing right ureteral stone.
 

Lupus Nephritis

New Lupus Nephritis Guidelines Issued

May 03, 2012

The American College of Rheumatology (ACR) has issued new guidelines for screening, treating, and managing lupus nephritis (LN), including methods of identifying kidney disease, newer therapies, and pregnant patient care.
 

Rituximab Ineffective as Lupus Nephritis Add-On Therapy

January 18, 2012

Adding rituximab to mycophenolate mofetil and corticosteroids does not improve outcomes in patients with lupus nephritis (LN), according to a study.
 

MMF Found Superior for Lupus Nephritis

November 28, 2011

Mycophenolate mofetil (MMF) is more effective than azathioprine as maintenance therapy for patients with active lupus nephritis (LN) who responded to induction therapy, researchers reported.
 

Secondary Hyperparathyroidism

High, Low PTH Raises Hypercalcemia Risk

May 13, 2012

NATIONAL HARBOR, Md.—Low and high levels of parathyroid hormone (PTH) are associated with hypercalcemia, according to a study of 106,760 hemodialysis patients presented at the National Kidney Foundation 2012 Spring Clinical Meetings suggest.
 

Novel Formulation Corrects Vitamin D, Lowers iPTH

May 13, 2012

NATIONAL HARBOR, Md.—An investigational treatment safely and effectively lowers elevated plasma intact parathyroid hormone (iPTH) levels in patients with stage 3 or 4 chronic kidney disease and vitamin D deficiency, researchers reported at the National Kidney Foundation 2012 Spring Clinical Meetings.
 

SHPT Linked to Vitamin D Deficiency in CKD Patients

May 12, 2012

NATIONAL HARBOR, Md.—Vitamin D deficiency is strongly associated with secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD), according to data presented at the National Kidney Foundation (NKF) 2012 Spring Clinical Meetings.
 

Transplantation

Renal Transplant Candidates Need Not Be Concerned About a Living Donor's Age

May 15, 2012

For most patients with end-stage renal disease patients (ESRD), the age of a living donor (ranging from 18-64 years) has an insignificant effect on the long-term health of a transplanted kidney, according to researchers in British Columbia, Canada.
 

Obesity a Barrier to Living Kidney Donation

May 13, 2012

NATIONAL HARBOR, Md.—Morbid obesity often is a barrier to living kidney donation, researchers reported at the National Kidney Foundation 2012 Spring Clinical Meetings.
 

PCa Patients on HD Would Benefit from Early Kidney Transplantation

May 12, 2012

NATIONAL HARBOR, Md.—Hemodialysis (HD) patients awaiting a kidney transplant must have a two-year cancer-free period immediately preceding transplantation.
 
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