Reduced Kidney Function Ups Likelihood of AFib

Over a median follow-up of 3.7 years, researchers observed 159 incident cases of atrial fibrillation.
Over a median follow-up of 3.7 years, researchers observed 159 incident cases of atrial fibrillation.

Decreased kidney function is a risk factor for atrial fibrillation, investigators reported in Nephrology (2016;21:717-720).

In a prospective study of 1840 patients aged 61–82 years, Jari Laukkanen, MD, of the University of Eastern Finland in Kuopio, Finland, and colleagues observed 159 incident cases of atrial fibrillation during a median follow-up of 3.7 years. Patients with a glomerular filtration rate of 15–59 mL/min/1.73 m2 estimated using cystatin C and creatinine measurements had a 2.7 and 2.4 times increased risk of atrial fibrillation, respectively, compared with those who had normal kidney function (90 mL/min/1.73 m2 or higher). Patients with a urinary albumin/creatinine ratio (ACR) of 300 mg/g or higher had a 2-fold increased risk of atrial fibrillation compared with those who had an ACR below 30 mg/g.


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