Minimal Priapism Risk with AndroGel 1% Use

Share this article:

Testosterone replacement with 1% testosterone gel (AndroGel 1%) is rarely associated with the development of priapism, according to a study.

Arthur L. Burnett, MD, of Johns Hopkins University in Baltimore, and colleagues reviewed the safety and tolerability data for AndroGel 1%, including data from three randomized controlled trials in varying populations of hypogonadal or near hypogonadal men. Of  283 men exposed to AndroGel 1% over the three trials, none reported experiencing adverse events described as priapism or related symptoms, researchers reported online ahead of print in the Journal of Sexual Medicine. The investigators also reviewed postmarketing data representing 40 million units sold and found only eight reports of cases described as priapism.

The researchers concluded from their findings that AndroGel 1% use is associated with a minimal risk of inducing priapism.

Share this article:
You must be a registered member of RUN to post a comment.

More in Hypogonadism

Hypogonadism May Raise Death Risk in Men with CKD

Hypogonadism May Raise Death Risk in Men with ...

Patients in the second lowest quintile of testosterone level had a 53% increased death risk compared with those in the highest quintile.

High Estradiol Boosts Libido in Men on Testosterone Therapy

High Estradiol Boosts Libido in Men on Testosterone ...

Elevated serum estradiol is associated with increased libido in men receiving TST.

FDA to Review Testosterone Therapy Safety

FDA to Review Testosterone Therapy Safety

Agency pointed to recent studies citing possible heightened heart risk tied to the treatments.