Lupus Nephritis

Rituximab Ineffective as Lupus Nephritis Add-On Therapy

January 18, 2012

Adding rituximab to mycophenolate mofetil and corticosteroids does not improve outcomes in patients with lupus nephritis (LN), according to a study.
 

MMF Found Superior for Lupus Nephritis

November 28, 2011

Mycophenolate mofetil (MMF) is more effective than azathioprine as maintenance therapy for patients with active lupus nephritis (LN) who responded to induction therapy, researchers reported.
 

Abatacept May Benefit Some Lupus Nephritis Patients

November 14, 2011

CHICAGO—Adding abatacept to mycophenolate mofetil (MMF) and steroids does not significantly improve the time to complete renal response in patients with lupus nephritis (LN), according to the findings of a 12-month study presented at the 2011 American College of Rheumatology annual meeting.
 

Vascular Biomarkers May Help Predict Lupus Nephritis Flares

November 14, 2011

CHICAGO—Vascular biomarkers may forecast impending flare or flare outcome in patients with lupus nephritis (LN), according to researchers in New York.
 

Biopsies May Predict Renal Outcomes in Patients with Lupus Nephritis

November 09, 2011

CHICAGO—Certain features at the time of renal biopsy are associated with a particular class of lupus nephritis (LN) and may independently predict good renal outcomes, according to a new Canadian study presented at the 2011 American College of Rheumatology Annual Scientific Meeting.
 

Prolonged Immunoadsorption Eases Lupus Nephritis

April 21, 2011

ATLANTA—Prolonged immunoadsorption (IAS) decreases proteinuria and leads to sustained stabilization of lupus nephritis in patients with highly active systemic lupus erythematosus (SLE), according to long-term results of a small Austrian study. The treatment did not result in tumors, anaphylaxis, or orthostatic events.
 

Big Drop in Lupus Nephritis Deaths Documented

February 24, 2011

ATLANTA—Mortality rates from lupus nephritis have decreased significantly since 1975 but have leveled off over the past 10 years, British researchers found.
 

Earlier Rituximab Better for Lupus Nephritis Patients

February 24, 2011

ATLANTA—Lupus nephritis patients who receive rituximab earlier in the course of their disease rather than later have better outcomes, new findings suggest.
 

Regimen May Improve Lupus Nephritis Care

February 07, 2011

ATLANTA—Enteric-coated mycophenolate sodium (EC-MPS) in combination with steroids is a viable therapy for lupus nephritis, according to an Italian study presented at the American College of Rheumatology annual meeting.
 

Low-Dose Combination May Be Effective for Refractory Lupus Nephritis

February 07, 2011

ATLANTA - A low-dose combination of mycophenolate mofetil (MMF) and tacrolimus (TAC) may be a viable option for treating refractory lupus nephritis, according to a new study by Chinese investigators.
 

Kidney Transplants Generally Safe for Lupus Patients

October 31, 2009

Contrary to previous studies, lupus patients who receive kidney transplants rarely develop lupus nephritis in their new allograft, according to a study presented at ASN's Renal Week conference.
 

Rituximab Eases Lupus Nephritis

September 21, 2009

Rituximab is an effective treatment for lupus nephritis that enables reductions in maintenance steroids, data show.
 

Fatal Infections Probed in Pediatric LN Patients

May 07, 2009

Prior history of treatment with pulse methylprednisolone may increase the risk of fatal infection in pediatric lupus nephritis (LN) patients treated with IV cyclophosphamide (IVCY), researchers reported.
 

Active Lupus Nephritis Raises Pregnancy Risks

March 23, 2009

Pregnant patients with active lupus nephritis have a higher incidence of maternal and fetal complications compared with patients who have systemic lupus erythematosus (SLE) without renal involvement, researchers reported in Lupus (2009;18:342-347).
 

In SLE, Renal Damage Is No. 1 Death Predictor

January 16, 2009

SAN FRANCISCO—Preventing renal damage in patients with systemic lupus erythematosus (SLE) may be critical to lowering their mortality rate, according to a new report.
 

Ongoing Lupus Nephritis Clinical Trials

ATLAS - Anti-Tweak in Lupus Nephritis Patients

Lupus Nephritis Biomarker Study: Baseline Characteristics of Patients

Weaning of Immunosuppression in Nephritis of Lupus (WIN-Lupus)

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