Lupus Nephritis Features

Physician Polls

Do you think patients with lupus nephritis can be good renal transplant candidates if their disease has been quiescent for at least one year?

In a recent study researchers examined transplant outcomes in patients with lupus nephritis who had no clinical evidence of disease in the year prior.

The Medical Minute A Clue to Black Lupus Patients' Higher Risk for ESRD

A Clue to Black Lupus Patients' Higher Risk for ESRD

Genetic changes may partly explain why African-Americans with lupus are up to five times more likely develop end-stage kidney disease.

CME Articles

An Update on the Management of Lupus Nephritis

Approximately 30%-50% of SLE patients have clinically evident renal disease at ­presentation, but renal involvement occurs in up to 60% of patients overall.

Latest Lupus Nephritis News

Kidney Disease Significantly Reduces Life Expectancy in SLE

Kidney Disease Significantly Reduces Life Expectancy in SLE

With systemic lupus erythematosus, kidney disease reduces life expectancy an average of 15 years

Kidney Involvement, High Anti-dsDNA Predict Lupus Flares

Kidney Involvement, High Anti-dsDNA Predict Lupus Flares

Predictors of moderate-severe SLE flare at week 52 identified using three indicators

Proteinuria Decline Linked to Improved Lupus Nephritis Outcomes

A 50% or greater reduction in proteinuria after six months of treatment for severe lupus nephritis predicted better 15-year renal survival.

Lupus Nephritis Need Not Prevent Renal Transplants

Lupus nephritis patients can be good candidates if their disease is quiescent for at least one year prior to surgery.

Systemic Lupus Erythematosus Flares Occur Despite Dialysis

SLE patients with renal failure often continue to experience flares, but most commonly these are serologic rather than clinical.

Abnormal SLE Serology Need Not Bar Pregnancy

If a lupus patient has never had renal disease, pregnancy, in and of itself, is not likely to increase that risk.

Proteinuria Recovery Heads Off LN Comorbidities

Even partial recovery in lupus nephritis patients lowers the risk of needing dialysis or a kidney transplant.

Lupus Nephritis Patient Genotype May Not Predict MMF Response

Lupus Nephritis Patient Genotype May Not Predict MMF Response

Effects of MMF may be influenced by the pathogenesis and/or cellular micro-environments unique to each disease process.

New Lupus Nephritis Guidelines Issued

The American College of Rheumatology (ACR) has issued new guidelines for screening, treating, and managing lupus nephritis (LN), including methods of identifying kidney disease, newer therapies, and pregnant patient care.

Rituximab Ineffective as Lupus Nephritis Add-On Therapy

Rituximab Ineffective as Lupus Nephritis Add-On Therapy

Adding rituximab to mycophenolate mofetil and corticosteroids does not improve outcomes in patients with lupus nephritis (LN), according to a study.

Black Race Worsens Transplant Outcomes

Black race is associated with worse renal transplant outcomes among patients with lupus nephritis and focal segmental glomerulosclerosis (FSGS), according to two studies presented at Kidney Week, the annual meeting of the American Society of Nephrology.

MMF Found Superior for Lupus Nephritis

Mycophenolate mofetil (MMF) is more effective than azathioprine as maintenance therapy for patients with active lupus nephritis (LN) who responded to induction therapy, researchers reported.

Abatacept May Benefit Some Lupus Nephritis Patients

CHICAGO—Adding abatacept to mycophenolate mofetil (MMF) and steroids does not significantly improve the time to complete renal response in patients with lupus nephritis (LN), according to the findings of a 12-month study presented at the 2011 American College of Rheumatology annual meeting.

Vascular Biomarkers May Help Predict Lupus Nephritis Flares

CHICAGO—Vascular biomarkers may forecast impending flare or flare outcome in patients with lupus nephritis (LN), according to researchers in New York.

Biopsies May Predict Renal Outcomes in Patients with Lupus Nephritis

Biopsies May Predict Renal Outcomes in Patients with Lupus Nephritis

CHICAGO—Certain features at the time of renal biopsy are associated with a particular class of lupus nephritis (LN) and may independently predict good renal outcomes, according to a new Canadian study presented at the 2011 American College of Rheumatology Annual Scientific Meeting.