Enteric-Coated Mycophenolate Sodium for Lupus Nephritis

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Nephrology. 2008; published online ahead of print

 

Enteric-coated mycophenolate sodium is effective and well-tolerated in patients with active lupus nephritis, Hong Kong researchers report.

 

Investigators at Kwong Wah Hospital in Kowloon retrospectively studied the treatment in 12 patients (mean age 32 years) with active lupus nephritis. The average length of follow-up was 26 months. Mycophenolate sodium was given for a mean of 13 months, with an average starting dose of 1,350 mg/day, in combination with corticosteroids. Six patients achieved complete remission and six achieved partial remission. The mean interval to the attainment of first remission was 8.3 weeks. Herpes zoster developed in one patient; no other significant adverse effects were observed.

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