KidneyWeek2016

Anemia in Non-Dialysis-Dependent CKD Patients Characterized

Anemia in Non-Dialysis-Dependent CKD Patients Characterized

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The condition is present in more than half of Medicare patients with stage 3-5 chronic kidney disease.

Anemia Linked to Vitamin D Insufficiency in Children With CKD

Anemia Linked to Vitamin D Insufficiency in Children With CKD

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Low vitamin D status was associated with a 2-fold higher risk for anemia.

Novel Drug Shows Promise for FSGS

Novel Drug Shows Promise for FSGS

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Sparsentan could become the first FDA-approved medication for the focal segmental glomerularsclerosis.

Bone Mass Increases After Total Parathyroidectomy

Bone Mass Increases After Total Parathyroidectomy

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In a study, 94.1% of total PTx patients had improvement of bone mineral density at their most affected site.

Parathyroidectomy Offers Survival Advantage

Parathyroidectomy Offers Survival Advantage

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Surgery decreased the risk of death from any cause by 32% compared with usual treatment.

Parathyroidectomy Rarely Achieves KDIGO Targets

Parathyroidectomy Rarely Achieves KDIGO Targets

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Just 6.7% of patients had target levels of calcium, phosphorus, and parathyroid hormone a year after surgery.

Novel Hyperkalemia Drug Has No Significant BP Effects Long-Term

Novel Hyperkalemia Drug Has No Significant BP Effects Long-Term

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Sodium zirconium cyclosilicate treatment for 12 months had no clinically meaningful effects on systolic or diastolic pressure, study finds.

Hyponatremia Identified as Kidney Stone Risk Factor

Hyponatremia Identified as Kidney Stone Risk Factor

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Studies also link kidney stone development to osteoporosis and proton pump inhibitor use.

Optimal Vitamin C Dose for Anemia in Hemodialysis Patients Unclear

Optimal Vitamin C Dose for Anemia in Hemodialysis Patients Unclear

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Pending future research, patients should avoid taking more than 120 mg per day.

Calciphylaxis Risk Higher in Peritoneal Dialysis Patients

Calciphylaxis Risk Higher in Peritoneal Dialysis Patients

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Their risk of the rare but life-threatening condition is twice as high as in hemodialysis patients.

Microwave Ablation Effective for Mild to Moderate SHPT

Microwave Ablation Effective for Mild to Moderate SHPT

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More patients treated with MWA plus calcitriol reached iPTH levels below 150 pg/mL: 23.33% vs 8.54%.

Early RRT for AKI May Lower Risk of Dialysis Dependence

Early RRT for AKI May Lower Risk of Dialysis Dependence

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It also may shorten intensive care unit and hospital length of stay versus late RRT in critically ill patients, meta-analysis reveals.

More Intensive Education on Diet, Binders Needed

More Intensive Education on Diet, Binders Needed

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Educated patients achieved better phosphate binder adherence.

Phosphate Enemas Can Cause Hyperphosphatemia

Phosphate Enemas Can Cause Hyperphosphatemia

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Purgative products introduce 10 times the normal daily amount of phosphorus into the body.

Dialysis Patient Age May Affect Hyperphosphatemia Management

Dialysis Patient Age May Affect Hyperphosphatemia Management

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Younger patients are less likely to respond to treatment with sucroferric oxyhydroxide or sevelamer.

Hypo- , Hyperkalemia Linked to ESRD

Hypo- , Hyperkalemia Linked to ESRD

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The risks of death from any cause were elevated by 22% and 31% for individuals with serum potassium levels of 5.5 mmol/L and 3.2 mmol/L, respectively, compared with 4.2 mmol/L.

Mortality Lower With Parathyroidectomy, Despite Lab Values

Mortality Lower With Parathyroidectomy, Despite Lab Values

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PTx patients had 15.7% lower odds of premature death.

Omega-3 Fatty Acids May Explain Hemodialysis Obesity Paradox

Omega-3 Fatty Acids May Explain Hemodialysis Obesity Paradox

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Study reveals a link between higher BMI in HD patients and greater incorporation of omega-3 fatty acids into red blood cell membranes.

Prescribed Meds May Up Phosphate Burden in Hemodialysis Patients

Prescribed Meds May Up Phosphate Burden in Hemodialysis Patients

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Study implicates amlodipine, lisinopril, clonidine, acetaminophen, and omeprazole.

Urea May Offer Cheaper Option for Long-Term SIADH Treatment

Urea May Offer Cheaper Option for Long-Term SIADH Treatment

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Researchers present results from the first long-term study of Urea USP in the United States.

Low, High Uric Acid Ups Post-ESRD Death Risk

Low, High Uric Acid Ups Post-ESRD Death Risk

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Levels of 10 mg/dL or higher and below 6 mg/dL predicted approximately 50% higher death risk in the 3 months after dialysis initiation.

More Cardiovascular Events Occur After Longer HD Schedule

More Cardiovascular Events Occur After Longer HD Schedule

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Cardiovascular events more than tripled 4 days following the last dialysis session.

Cinacalcet Initiated at Varying PTH Levels

Cinacalcet Initiated at Varying PTH Levels

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Prior to starting therapy, parathyroid hormone trajectories show different patterns of increase and decrease.

Phosphate Binder Switch Found to Benefit Peritoneal Dialysis Patients

Phosphate Binder Switch Found to Benefit Peritoneal Dialysis Patients

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The percentage of patients with serum phosphorus levels of 5.5 mg/dL and below more than doubled to 37.8% after 6 months of treatment with sucroferric oxyhydroxide.

Sucroferric Oxyhydroxide Helps More Hyperphosphatemia Pts Reach Target

Sucroferric Oxyhydroxide Helps More Hyperphosphatemia Pts Reach Target

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Patients also needed fewer phosphate binder pills over time.

Hyperkalemia Increases Death Risk

Hyperkalemia Increases Death Risk

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Death risk increased markedly once serum potassium values exceeded 5.5 mEq/L.

High Intact Parathyroid Hormone Levels Linked With Death in CKD

High Intact Parathyroid Hormone Levels Linked With Death in CKD

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Having 3 or 4 CKD-MBD markers in the danger zone more than doubled the chances of early death.

Microalbuminuria On the Rise Among Healthy Obese Individuals

Microalbuminuria On the Rise Among Healthy Obese Individuals

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From 2001 to 2014, the prevalence of microalbuminuria among obese individuals without other comorbidities increased from 3.2% to 8.1%.

Study Reveals Vitamin D Therapy Effect on Mineral Biomarkers

Study Reveals Vitamin D Therapy Effect on Mineral Biomarkers

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Calcitriol and paricalcitol raise levels of fibroblast growth factor 23 and sclerostin and lower levels of some bone turnover markers.

Blood Pressure Reductions With Patiromer Possibly Explained

Blood Pressure Reductions With Patiromer Possibly Explained

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Evidence suggests decreased sodium absorption could be a contributing factor in at least some patients.

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