KidneyWeek2015

Lower Pre-ESRD Hemoglobin Predicts Better Dialysis Patient Survival

Lower Pre-ESRD Hemoglobin Predicts Better Dialysis Patient Survival

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Having hemoglobin 9-11 g/dL prior to dialysis provided the best life expectancy.

Red Cell Distribution Width Linked With Mortality in Dialysis

Red Cell Distribution Width Linked With Mortality in Dialysis

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It is unclear whether RDW is a risk factor for early death or a byproduct of biological and metabolic imbalances.

Higher Triglycerides Linked With Lower Mortality in Early Dialysis

Higher Triglycerides Linked With Lower Mortality in Early Dialysis

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Veteran patients with levels below 100 mg/dL had a 26% higher risk of mortality compared with patients with triglyceride levels of 150-200 mg/dL.

Hepatitis, CMV More Common in Commercial Transplants

Hepatitis, CMV More Common in Commercial Transplants

Overall one- and ten-year survival rates of the transplanted organs in commercial recipients compared with controls were 91% and 22% vs. 98% and 44%.

Statins May Improve Response to Erythropoiesis-Stimulating Agents

Statins May Improve Response to Erythropoiesis-Stimulating Agents

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Patients prescribed the lipid-lowering agents were less likely to exhibit hyporesponsiveness to the medications.

Moderate Ascorbic Acid Supplementation Safe, Effective in HD Patients

Moderate Ascorbic Acid Supplementation Safe, Effective in HD Patients

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Up to 100 mg per day raises plasma concentrations of ascorbic acid without increasing oxalate levels.

Erythropoietin Resistance More Likely in Female Dialysis Patients

Erythropoietin Resistance More Likely in Female Dialysis Patients

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Study finds no gender differences in parathyroid hormone, ferritin, Kt/V, or age.

Opioid Effective for Uremic Pruritus in Hemodialysis Patients

Opioid Effective for Uremic Pruritus in Hemodialysis Patients

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In an 8-week randomized trial, extended-release nalbuphine 120 mg BID significantly reduced itch severity compared with placebo.

Vitamin C Found to Decrease Erythropoietin Requirement

Vitamin C Found to Decrease Erythropoietin Requirement

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In a study, the mean hemoglobin level increased significantly in hemodialysis patients with functional iron deficiency.

Wearable Artificial Kidney Has Successful Human Trial

Wearable Artificial Kidney Has Successful Human Trial

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In a 24-hour exploratory trial, all 7 patients who wore the device remained hemodynamically stable over the study period.

Hyponatremia Prevalence in CKD Patients Characterized

Hyponatremia Prevalence in CKD Patients Characterized

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It develops in 8% of patients overall and 15.1% of patients with stage 5 CKD.

Phosphate Binders Show Similar Efficacy in African Americans

Phosphate Binders Show Similar Efficacy in African Americans

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Study compared sucroferric oxyhydroxide and sevelamer carbonate.

Hypernatremia May Lead to Early Death

Hypernatremia May Lead to Early Death

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Caring for hypernatremia patients also involved greater resource consumption.

Acute Kidney Injury More Likely in African Americans

Acute Kidney Injury More Likely in African Americans

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Increased risk observed in the VA health system unlikely to be fully explained by disparities in access to care.

CKD Severity Linked to Low BMD, Hip Fracture, and Mortality

CKD Severity Linked to Low BMD, Hip Fracture, and Mortality

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The risk of dying following a hip fracture was 6.5 times higher for patients with severe CKD than for those with normal kidney function or mild CKD.

CKD-MBD May Play Role in Restless Legs Syndrome in Dialysis Patients

CKD-MBD May Play Role in Restless Legs Syndrome in Dialysis Patients

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Phosphate and vitamin D deficiency were linked with RLS severity.

High Phosphorus, Cerebral Hemorrhage Linked in HD Patients

High Phosphorus, Cerebral Hemorrhage Linked in HD Patients

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Researchers observe a 2.2-fold increased risk in patients with serum phosphate levels of 6.0 mg/dL or higher.

High Phosphate Increases Mortality Risk in CKD Patients

High Phosphate Increases Mortality Risk in CKD Patients

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Meta-analysis finds that each 1 mg/dL increase in serum phosphate increases the risk of death by 23%.

Tolvaptan May Offer Way to Lower Kidney Stone Risk

Tolvaptan May Offer Way to Lower Kidney Stone Risk

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Study shows that it increases urine volume and decreases supersaturation with stone-forming calcium salts.

Vascular Lesions in Renal Biopsy Specimens Predict CV Events

Vascular Lesions in Renal Biopsy Specimens Predict CV Events

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Significant association found in patients with diabetic nephropathy.

Iron Deficiency Ups Mortality in Renal Transplant Recipients

Iron Deficiency Ups Mortality in Renal Transplant Recipients

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The association is independent of anemia, according to researchers.

Acute Kidney Injury Raises Heart Failure Risk

Acute Kidney Injury Raises Heart Failure Risk

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AKI is independently associated with a 27% increased risk of heart failure, according to a study of hospitalized U.S. veterans.

Acute Kidney Injury Risk Relatively Low After GI Surgery

Acute Kidney Injury Risk Relatively Low After GI Surgery

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AKI developed in 2.1% of operations and was more common after major, open, and acute surgeries.

Hyponatremia at Hemodialysis Initiation Increases Death Risk

Hyponatremia at Hemodialysis Initiation Increases Death Risk

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Serum sodium levels below 130 mEq/L were associated with a 2.3 times increased risk of death compared with levels of 136-145 mEq/L.

Low Magnesium Ups Cardiovascular Death Risk

Low Magnesium Ups Cardiovascular Death Risk

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Study finds a 42% increased risk of death from coronary heart disease and 68% increased risk of sudden cardiac death.

Anemia More Severe in Hemodialysis Patients with PEW

Anemia More Severe in Hemodialysis Patients with PEW

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Patients with vs. without protein-energy wasting syndrome had a significantly lower mean hemoglobin level.

Home Dialysis Use Declines in Wake of Payment Reform

Home Dialysis Use Declines in Wake of Payment Reform

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Medicare patients affected by the reform experienced a 12% decrease in the odds of home dialysis use compared those unaffected by the reform.

HCV Ups Anemia-Related Event Risks in Hemodialysis Patients

HCV Ups Anemia-Related Event Risks in Hemodialysis Patients

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Hepatitis C viral infection found to increase likelihood of requiring blood transfusions and hemoglobin levels dropping below 8.5 g/dL.

Sucroferric Oxyhydroxide Reduces Phosphorus, Binder Pill Burden

Sucroferric Oxyhydroxide Reduces Phosphorus, Binder Pill Burden

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Researchers observe a significant mean decrease in binder pills from 8.4 to 3.8 pills per day.

HD Patients with Lowest FGF-23 Level Have Lowest Survival Rate

HD Patients with Lowest FGF-23 Level Have Lowest Survival Rate

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Cumulative 2-year survival rate was 65.4%, 78.9%, 85.1%, and 80.6% among patients in the 1st, 2nd, 3rd, and 4th quartiles.

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