Waist-to-hip Ratio Predicts CV Mortality in Hemodialysis Patients
Each 0.1 increase in WHR is associated with a 1.7-fold increased risk of cardiovascular death.
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NEW ORLEANS—Waist-to-hip ratio (WHR) may be a useful way to assess cardiovascular risks among patients on hemodialysis, investigators reported at the American Society of Nephrology's Kidney Week 2017 meeting.
In a study of 379 incident HD patients enrolled in the Predictors of Arrhythmic and Cardiovascular Risk in ESRD [end-stage renal disease] study, Jessica Fitzpatrick, MD, of the University of Toronto, and colleagues found that each 0.1 increase in WHR was associated with a significant 1.7- and 2.5 fold increased risk for cardiovascular (CV) death and sudden cardiac death, respectively, in adjusted analyses. WHR was not associated with deaths from non-CV causes.
The study population had a mean age of 54.9 years. The mean WHR was 0.95, and 85% of patients were above the World Health Organization WHR threshold for metabolic complications. During a median follow-up of 2.5 years, the study population had 35 CV deaths, 15 SCDs, and 48 deaths from non-CV causes.
The authors concluded that WHR may be a useful metric to risk stratify ESRD patients for CV mortality.
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Fitzpatrick J, Sozio SM, Jaar BG, et al. Association of waist-to-hip ratio with sudden cardiac death and cardiovascular mortality in incidence hemodialysis patients. Presented in poster format at Kidney Week 2017 in New Orleans (Oct. 31 to Nov. 5). Poster FR-PO835.