CKD Risk Higher Among Diabetic Women than Men

ATLANTA—Chronic kidney disease (CKD) is more likely to develop in diabetic women than diabetic men, according to a study presented at the American Society of Nephrology's Kidney Week 2013 meeting.

The study, by Margaret K. Yu, MD, and Bessie A. Young, MD, MPH, of the University of Washington in Seattle, included 1,468 diabetic patients, of whom 766 (52.2%) were women.

Women study had a 33% greater risk of incident CKD at 10 years after taking into account pre-CKD death as a competing risk and after adjusting for demographics, traditional risk factors, and behavioral risk factors.

“Diabetic women may represent a high risk group for the development of CKD,” the authors concluded.

They noted that women with diabetes have a higher prevalence of CKD risk factors than men.

Women were more likely to be unmarried, have lower education levels, higher low-density lipoprotein, body mass index, and baseline estimated glomerular filtration rate (eGFR) compared with men.

Participants were identified through the Pathways Study, a Seattle-based prospective, observational cohort of ambulatory, diabetic patients. Only patients without baseline CKD were observed for 10-year incidence. CKD was defined as an eGFR less than 60 mL/min/1.73 m2 or microalbuminuria (urine albumin/creatinine value of 25 mg/g or more for women or 17 mg/g or more for men.

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