Kidney Cancer

Researchers Calculate Inherited Cancer Risk from Genes

Researchers Calculate Inherited Cancer Risk from Genes

Estimated 33% of overall risk is genetic; certain types of cancer have additional risk.

NSAIDs May Raise Risk of Fatal Kidney Cancer

NSAIDs May Raise Risk of Fatal Kidney Cancer

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Regular use of non-steroidal anti-inflammatory drugs for 10 years or more increased the risk of dying from renal cell carcinoma nearly 4-fold.

Nephrectomy as Initial mRCC Treatment Offers Survival Advantage

Nephrectomy as Initial mRCC Treatment Offers Survival Advantage

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Patients who underwent upfront cytoreductive nephrectomy lived 6.4 months longer than those treated with upfront targeted therapy, a study found.

Metformin Lowers Death Risk in mRCC Patients on Sunitinib

Metformin Lowers Death Risk in mRCC Patients on Sunitinib

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The protective effect was not observed with other anti-diabetic medications.

Cabozantinib Improves PFS in Patients With Advanced RCC

Cabozantinib Improves PFS in Patients With Advanced RCC

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The drug nearly doubled the delay in tumor growth compared with everolimus.

RCC Surgery Outcomes Not Worse in Extremely Obese Patients

RCC Surgery Outcomes Not Worse in Extremely Obese Patients

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Study reveals no significant differences in hospital readmission rates and overall, cancer-specific, and recurrence-free survival rates.

FDA Approves New Drug for Advanced Kidney Cancer

FDA Approves New Drug for Advanced Kidney Cancer

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Nivolumab is cleared for treating patients with metastatic RCC whose disease advanced despite prior treatment with anti-angiogenic therapy.

Diabetes Predicts Worse Survival in RCC Patients Treated Surgically

Diabetes Predicts Worse Survival in RCC Patients Treated Surgically

For patients with diabetes, poor glycemic control linked to higher risk of post-operative progression.

Type 1, Type 2 Papillary Renal Cell Carcinomas Biologically Distinct

Type 1, Type 2 Papillary Renal Cell Carcinomas Biologically Distinct

Specific alterations seen in type 1 and type 2 carcinomas; type 2 consists of at least 3 subtypes.

ESRD and Treatments May Raise Cancer Risk

ESRD and Treatments May Raise Cancer Risk

Dialysis, organ transplant may increase odds for certain types of cancer.

Barbecued, Pan-Fried Meat May Raise Renal Cell Carcinoma Risk

Barbecued, Pan-Fried Meat May Raise Renal Cell Carcinoma Risk

High-heat cooking methods implicated in new study.

Sunitinib Toxicities May Predict Better mRCC Patient Survival

Sunitinib Toxicities May Predict Better mRCC Patient Survival

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On-treatment neutropenia and hypertension are independently associated with decreased mortality risk.

Kidney Cancer Death Less Likely with Local Tumor Ablation

Kidney Cancer Death Less Likely with Local Tumor Ablation

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Researchers report a survival advantage over observation among elderly patients with localized tumors.

Myopathy in Patient With Nivolumab-Related Respiratory Symptoms

Myopathy in Patient With Nivolumab-Related Respiratory Symptoms

Case report describes 84-year-old male patient with myositis after nivolumab treatment.

Sorafenib, Sunitinib May Pose Cardiovascular Risk

Sorafenib, Sunitinib May Pose Cardiovascular Risk

Higher stroke risk found in older kidney cancer patients taking the drugs.

New Model More Accurately Predicts mRCC Patient Survival

New Model More Accurately Predicts mRCC Patient Survival

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The model incorporates 2 newly identified independent mortality risk factors in patients requiring second-line targeted therapy.

Surveillance Superior to Radical Nephrectomy for Small Renal Masses

Surveillance Superior to Radical Nephrectomy for Small Renal Masses

Active surveillance equal to partial nephrectomy for renal function preservation.

Nivolumab, Cabozantinib Improve Outcomes in Advanced Kidney Cancer

Nivolumab, Cabozantinib Improve Outcomes in Advanced Kidney Cancer

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In separate studies, nivolumab prolonged overall survival and cabozantinib improved progression-free survival compared with everolimus.

mRCC Patient Survival Improving

mRCC Patient Survival Improving

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Trend mirrors move to targeted therapy era.

Smoking Increases Risk of Some Renal Cell Cancer Subtypes

Smoking Increases Risk of Some Renal Cell Cancer Subtypes

Higher risk for clear cell, papillary renal cell carcinoma, but not chromophobe histology.

Child Cancer Survivors at Increased Risk for Neoplasm in Adulthood

Child Cancer Survivors at Increased Risk for Neoplasm in Adulthood

Increased risk for treatment-related subsequent neoplasms even beyond age 40 years.

Delayed mRCC Therapy Benefits Selected Patients

Delayed mRCC Therapy Benefits Selected Patients

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Quality of life can be improved without adversely affecting outcomes.

NLR Predicts GU Cancer Outcomes After Treatment

NLR Predicts GU Cancer Outcomes After Treatment

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New data suggest a prognosis role for the neutrophil to lymphocyte ratio.

Robotic Surgery Possible for Inferior Vena Cava Tumor Thrombectomy

Robotic Surgery Possible for Inferior Vena Cava Tumor Thrombectomy

Completely intracorporeal robotic level III inferior vena cava tumor thrombectomy viable.

Cancer Trials Should Involve More Seniors, ASCO Says

Cancer Trials Should Involve More Seniors, ASCO Says

Older adults react differently to treatment, oncology group notes.

Many Cancer Patients Unaware of Ways to Preserve Fertility

Many Cancer Patients Unaware of Ways to Preserve Fertility

Almost 1 in 3 not told cancer treatment might affect future fertility.

Chemo Doesn't Improve Quality of Life in End-Stage Cancer

Chemo Doesn't Improve Quality of Life in End-Stage Cancer

No improvement in quality of life, even for patients with good baseline performance status.

ESRD Risk with Radical and Partial Nephrectomy Comparable

ESRD Risk with Radical and Partial Nephrectomy Comparable

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Radical and partial nephrectomy for renal cell carcinoma are associated with a similar risk of end-stage renal disease (ESRD), according to research.

Vitamin E May Protect Against Kidney Cancer

Vitamin E May Protect Against Kidney Cancer

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High dietary intake of this antioxidant decreased the risk of renal cell carcinoma, according to a recent meta-analysis.

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