Kidney Cancer

ESRD Risk with Radical and Partial Nephrectomy Comparable

ESRD Risk with Radical and Partial Nephrectomy Comparable

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Radical and partial nephrectomy for renal cell carcinoma are associated with a similar risk of end-stage renal disease (ESRD), according to research.

Vitamin E May Protect Against Kidney Cancer

Vitamin E May Protect Against Kidney Cancer

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High dietary intake of this antioxidant decreased the risk of renal cell carcinoma, according to a recent meta-analysis.

Local Tumor Ablation of Small Renal Masses Offers Survival Edge

Local Tumor Ablation of Small Renal Masses Offers Survival Edge

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In a study, the treatment was associated with a 53% decreased risk of death from kidney cancer compared with expectant management.

Combo Therapy Nonsuperior to Bevacizumab Monotherapy in RCC

Combo Therapy Nonsuperior to Bevacizumab Monotherapy in RCC

Bevacizumab, sorafenib, and temsirolimus combinations did not improve progression-free survival in renal cell carcinoma (RCC).

Smoking Responsible for Many Deaths from 12 Cancers

Smoking Responsible for Many Deaths from 12 Cancers

80% of lung cancer deaths linked to smoking, researchers say.

Factors Affecting Survival After Surgery for Locally Advanced RCC

Factors Affecting Survival After Surgery for Locally Advanced RCC

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Asymptomatic presentation, T3 low-grade tumors, and negative lymph nodes are associated with better progression-free and overall survival.

Urinary Cancers Not Linked to Lithium

Urinary Cancers Not Linked to Lithium

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Study findings contradict those of previous investigators.

Cancer Patients Would Pay for Tumor Genetic Profiling

Cancer Patients Would Pay for Tumor Genetic Profiling

Two-thirds of patients feel that tumor profiling could improve their treatment; many will pay out of pocket.

Optimal RCC Tumor Shrinkage Threshold for Prognosis Should Be Lower

Optimal RCC Tumor Shrinkage Threshold for Prognosis Should Be Lower

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Data suggest that a 7% or 8% cut-off rather than the conventional 30% is a better predictor in patients treated for mRCC.

Early Tumor Shrinkage with TKIs Predicts mRCC Survival

Early Tumor Shrinkage with TKIs Predicts mRCC Survival

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RCC tumor shrinkage significantly and independently predicted overall survival.

Neoadjuvant Sunitinib Linked to Improved Outcomes in RCC with Thrombus

Neoadjuvant Sunitinib Linked to Improved Outcomes in RCC with Thrombus

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Neoadjuvant sunitinib was linked to primary tumor and thrombus shrinkage, reduced blood loss during surgery, as well as improved cancer-specific survival.

RCC Progression Rare After 10 Recurrence-Free Years Post-Nephrectomy

RCC Progression Rare After 10 Recurrence-Free Years Post-Nephrectomy

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Pathological stage was the only independent factor linked to kidney cancer progression.

Intensive Local Therapy to RCC Bone Metastases May Increase Survival

Intensive Local Therapy to RCC Bone Metastases May Increase Survival

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The approach was defined as surgical resection with a wide margin or radiotherapy with a biologically effective dose of 140 Gy or greater.

Metastasectomy May Up Survival in Metastatic RCC Patients

Metastasectomy May Up Survival in Metastatic RCC Patients

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In a study, patients who had the procedure had a better 5-year overall survival rate than those who did not (68% vs. 27%).

Larger RCC Tumors Predict High-Grade Pathology

Larger RCC Tumors Predict High-Grade Pathology

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New finding may inform treatment decisions.

Socioeconomic Predictors of Metastatic Clear-Cell RCC Identified

Socioeconomic Predictors of Metastatic Clear-Cell RCC Identified

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It is important to assess factors that may put patients at higher risk of metastatic disease, according to researchers.

Renal Tumor Biopsy Urged for Small Renal Masses

Renal Tumor Biopsy Urged for Small Renal Masses

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In a study, treatment could have been avoided in at least 26% of cases because a biopsy revealed a benign lesion, researchers reported.

Genetic Tests Should Include Normal and Cancerous Tissue

Genetic Tests Should Include Normal and Cancerous Tissue

Current practice of only focusing on tumor samples might adversely affect care.

Survival Similar with Renal Cryo Techniques

Survival Similar with Renal Cryo Techniques

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Lapascopic and percutaneous cryoablation for small renal masses are associated with similar survival, researchers say.

Fish Oil Might Reduce Chemo's Effectiveness

Fish Oil Might Reduce Chemo's Effectiveness

Research raises concern about the simultaneous use of chemotherapy and fish oil.

Partial Nephrectomy Does Not Eliminate CKD Risk

Partial Nephrectomy Does Not Eliminate CKD Risk

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The risk is particularly elevated for patients who have CKD risk factors, such as hypertension, diabetes, and older age.

Urine Biomarkers May Diagnose Renal Cell Carcinoma

Urine Biomarkers May Diagnose Renal Cell Carcinoma

Urine aquaporin-1 and perilipin-2 may have utility as biomarkers for diagnosing malignant clear cell or papillary renal cell carcinoma (RCC).

Statins Promising for Cancers

Statins Promising for Cancers

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Studies suggest that these cholesterol-lowering drugs can improve treatment of genitourinary cancers and prevent contrast-induced nephropathy.

Obese Women Have Higher Odds of Kidney Cancer, More

Obese Women Have Higher Odds of Kidney Cancer, More

However, researchers stress that losing excess weight can lower the cancer odds.

Risk Factors for Late RCC Recurrence Identified

Risk Factors for Late RCC Recurrence Identified

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Patients with these risk factors should be followed up for the rest of their lives, according to the researchers.

High BMI a Plus for Some Metastatic Kidney Cancer Patients

High BMI a Plus for Some Metastatic Kidney Cancer Patients

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Overweight or obese patients treated with targeted therapy for metastatic clear-cell renal cell carcinoma found to live longer.

Statins May Prolong Life in Patients with Advanced Kidney Cancer

Statins May Prolong Life in Patients with Advanced Kidney Cancer

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In a study of 4,736 patients with metastatic renal cell carcinoma, use of the drugs was associated with a nearly 22% decreased risk of death.

Adjuvant Kidney Cancer Drugs Fail to Improve Outcomes

Adjuvant Kidney Cancer Drugs Fail to Improve Outcomes

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Sorafenib or sunitinib given after surgery for advanced renal cell carcinoma does not improve progression-free survival, study shows.

Genitourinary Cancer in Siblings Raises Personal Risk

Genitourinary Cancer in Siblings Raises Personal Risk

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Researchers found elevated familial risks for testicular, prostate, bladder, and kidney cancers.

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