RCC tumor shrinkage significantly and independently predicted overall survival.
Neoadjuvant sunitinib was linked to primary tumor and thrombus shrinkage, reduced blood loss during surgery, as well as improved cancer-specific survival.
Pathological stage was the only independent factor linked to kidney cancer progression.
The approach was defined as surgical resection with a wide margin or radiotherapy with a biologically effective dose of 140 Gy or greater.
In a study, patients who had the procedure had a better 5-year overall survival rate than those who did not (68% vs. 27%).
New finding may inform treatment decisions.
It is important to assess factors that may put patients at higher risk of metastatic disease, according to researchers.
In a study, treatment could have been avoided in at least 26% of cases because a biopsy revealed a benign lesion, researchers reported.
Current practice of only focusing on tumor samples might adversely affect care.
Lapascopic and percutaneous cryoablation for small renal masses are associated with similar survival, researchers say.
Research raises concern about the simultaneous use of chemotherapy and fish oil.
The risk is particularly elevated for patients who have CKD risk factors, such as hypertension, diabetes, and older age.
Urine aquaporin-1 and perilipin-2 may have utility as biomarkers for diagnosing malignant clear cell or papillary renal cell carcinoma (RCC).
Studies suggest that these cholesterol-lowering drugs can improve treatment of genitourinary cancers and prevent contrast-induced nephropathy.
However, researchers stress that losing excess weight can lower the cancer odds.
Patients with these risk factors should be followed up for the rest of their lives, according to the researchers.
Overweight or obese patients treated with targeted therapy for metastatic clear-cell renal cell carcinoma found to live longer.
In a study of 4,736 patients with metastatic renal cell carcinoma, use of the drugs was associated with a nearly 22% decreased risk of death.
Sorafenib or sunitinib given after surgery for advanced renal cell carcinoma does not improve progression-free survival, study shows.
Researchers found elevated familial risks for testicular, prostate, bladder, and kidney cancers.
Risk factors include male gender, distant disease, increasing age, race/ethnicity
Data reveal no significant differences in overall and cancer-specific survival at 5 years.
In a study of post-menopausal women, the highest quartile of lycopene intake was associated with a significant 39% decreased risk of renal cell carcinoma versus the lowest quartile.
98% of the renal tumors were controlled at 9 months after treatment.
Nephron-sparing approach is associated with a 56% decreased risk of postoperative end-stage renal disease versus radical surgery.
Robot-assisted surgery increases access to partial nephrectomy for appropriate patients.
In community practice, overall rate of compliance with AUA Best Practices is less than 60 percent
Low serum albumin levels increase the risk of death in patients undergoing cytoreductive nephrectomy for metastatic renal cell carcinoma.
Medical marijuana may be beneficial for nausea and vomiting, pain and weight loss, but more research is needed to determine potential harms.
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NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)