Patients who underwent radical nephrectomy had 2-fold greater decline in eGFR decline and 2-fold greater mortality compared with those who had a partial nephrectomy.
Patients who received cabozantinib were also less likely to have skeletal-related events (23% vs 29% with everolimus).
Renal & Urology News spoke with Jonathan Silberstein, MD, about creating surgical models using a 3D printer.
Stereotactic ablative radiotherapy is associated with high 2- and 4-year rates of local cancer control and progression-free and cancer-specific survival.
In a multinational, prospective study, just 5% of cases converted.
Most patients with cancer, autoimmune disease have improvement in events without discontinuing therapy.
Although TKIs improve outcomes, they are still associated with toxicities common with cancer therapies, such as fatigue.
Partial nephrectomy was associated with decreased odds of death versus radical nephrectomy among patients with cT1b but not cT2 renal cell carcinoma.
Treatment with cabozantinib led to a clinically meaningful improvement in progression-free survival compared with sunitinib.
Patients who underwent cytoreductive nephrectomy for metastatic non-clear cell renal cell carcinoma had a significantly decreased risk of cancer-related mortality.
Levels of alkaline phosphatase, calcium, and hemoglobin can independently predict bone metastasis in patients with renal cell carcinoma, Chinese investigators report.
At 5 years, 59.3% of patients treated with sunitinib were free from recurrence versus 51.3% who received placebo.
Robotic-assisted radical nephrectomy (RN) is associated with higher hospital costs and prolonged operating time compared with laparoscopic RN.
Perioperative blood transfusion is associated with increased risks of tumor recurrence, metastatic progression, and cancer-related mortality.
40% of cancer diagnoses tied to extra weight; rate higher in older individuals, females.
Patients with papillary versus clear cell renal cell carcinoma have a 24% decreased risk of dying from their cancer.
In a study, partial nephrectomy was associated with a 66% lower risk for stage 4 or higher CKD versus radical nephrectomy.
The researchers found that 2.9% of the 347 patients treated with anti-PD-1 monoclonal antibodies developed subacute onset of neurological complications.
Mvasi, which is approved to treat colorectal, lung, brain, kidney, and cervical cancer, was found to be biosimilar to the drug Avastin.
Checkpoint inhibitor combination of nivolumab plus ipilimumab improved progression-free and overall survival compared with sunitinib.
Cabozantinib reduced the risk of disease progression or death compared with sunitinib among patients with previously untreated advanced renal cell carcinoma.
Rises and decreases in neutrophil-to-lymphocyte ratio at 6 weeks after treatment with anti-PD-1/PD-L1 immune checkpoint blockade is associated with progression-free and overall survival.
The increased risk for obesity-related cancer was seen among women who were normal weight at enrollment.
Participant age and comorbidity burden appeared to be consistent determinants of use of services, although hospital-level variation was also noted.
Response rates of the combination therapy increasing from 20% to 40%.
The most commonly altered genes were folliculin and fumarate hydratase in 1.8% and 1.3%, respectively.
Nivolumab combined with ipilimumab revealed manageable safety, antitumor activity and favorable responses garnering potential long-term benefits.
Patients who have a complete response to 2 or more years of anti-VEGF treatment have the best progression-free and overall survival.
Both urologists and nephrologists provide follow-up and continuity of care to patients after cancer nephrectomy.
BMI and location of excess body fat on the body are good indicators of obesity-related cancer risk.
Renal and Urology News Articles
- CROWNWeb Reporting Gets Up to Speed With Implementation of Dashboard
- Prostate Cancer Gene Testing Guidelines Issued
- Radical Nephrectomy Linked With Worse Kidney Function, Survival
- Acute Kidney Injury Increases Risk for Hypoglycemia in Diabetes Pts
- USPSTF Questions Nontraditional CVD Risk Factors for Assessment
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NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)