Kidney Cancer

Are you surprised that targeted therapeutics for metastatic renal cell carcinoma (RCC) have not improved survival?

Are you surprised that targeted therapeutics for metastatic renal cell carcinoma (RCC) have not improved survival?

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A study found that targeted therapeutic agents for treating metastatic RCC has not led to an improvement in survival rates.

Post-Transplant Urologic Cancers More Likely in Women

Post-Transplant Urologic Cancers More Likely in Women

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In adjusted analyses, female transplant recipients had a significantly increased risk of urologic cancer and men did not.

Kidney, Thyroid Cancers on the Rise in Children

Kidney, Thyroid Cancers on the Rise in Children

Study also finds increase in overall cancer rate among African-American children and adolescents.

Chronic Kidney Disease (CKD) Predicts Acute Kidney Injury (AKI) After Renal Cell Carcinoma Surgery

Chronic Kidney Disease (CKD) Predicts Acute Kidney Injury (AKI) After Renal Cell Carcinoma Surgery

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Other predictors include neurovascular disease, obesity, and surgical approach.

Advanced Kidney Cancer Survival Rates Not Improved

Advanced Kidney Cancer Survival Rates Not Improved

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The 3-year survival rates for patients diagnosed during 2006-2007 were similar to those diagnosed during 2001-2005.

Depression in Cancer Patients Often Untreated

Depression in Cancer Patients Often Untreated

Studies show integrated program effective for depression in patients with cancer.

High CRP Predicts Poor RCC-Specific Survival in Hemodialysis Patients

High CRP Predicts Poor RCC-Specific Survival in Hemodialysis Patients

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Study shows a 3.5 times increased risk of death from renal cancer in hemodialysis patients undergoing nephrectomy.

End-Stage Renal Disease (ESRD) Risk Lower with Partial Nephrectomy

End-Stage Renal Disease (ESRD) Risk Lower with Partial Nephrectomy

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Researchers find a greater than 50% reduction in end-stage renal disease risk compared with radical nephrectomy.

Obesity Ups Bladder, Kidney Cancer Risk in Men

Obesity Ups Bladder, Kidney Cancer Risk in Men

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As body mass index increases, so does the risk of kidney and bladder cancers in men and stomach, ovarian, and colon cancers in women.

Prostate Cancer Patients Face Higher Risk of Second Malignancies

Prostate Cancer Patients Face Higher Risk of Second Malignancies

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Study reveals a 2-fold greater likelihood of primary kidney and bladder cancer compared with men in the general population.

Visceral Fat Area Predicts Kidney Cancer Subtype

Visceral Fat Area Predicts Kidney Cancer Subtype

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Increased abdominal adiposity is associated with a greater likelihood of clear-cell renal cell carcinoma.

Partial Nephrectomy Superior Despite Kidney Tumor Size

Partial Nephrectomy Superior Despite Kidney Tumor Size

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Renal function is preserved better compared with radical nephrectomy even when tumors are larger than the traditional 4 cm cutoff.

Renal Tumor Risk Higher in Lithium-Treated Patients

Renal Tumor Risk Higher in Lithium-Treated Patients

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Renal tumors occur at a frequency 7.5 times greater in lithium-treated patients than in the general population, French study shows.

Nephron Sparing Surgery Okay for Tumors in Transplanted Kidneys

Nephron Sparing Surgery Okay for Tumors in Transplanted Kidneys

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At last follow-up, 41 of 43 patients who underwent partial nephrectomy did not require dialysis.

High Cholesterol Predicts Better RCC Outcomes

High Cholesterol Predicts Better RCC Outcomes

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Patients with levels of 161.5 mg/dL or greater had a 43% decreased risk of death from renal cell carcinoma than those with lower levels.

Pre-Existing HTN Predicts Better Survival in Sunitinib Recipients

Pre-Existing HTN Predicts Better Survival in Sunitinib Recipients

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The finding emerged from a French study of 213 patients with metastatic renal cell carcinoma.

Autologous Immunotherapy for mRCC Shows Promise

Autologous Immunotherapy for mRCC Shows Promise

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Added to sunitinib, it prolongs progression-free and overall survival in patients with unfavorable-risk metastatic renal cell carcinoma.

TSC-Related Pediatric Renal Tumors Respond to Everolimus

TSC-Related Pediatric Renal Tumors Respond to Everolimus

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Drug found to benefit children with renal angiomyolipomas associated with tuberous sclerosis complex.

Shorter RCC Recurrence Time Ups Risk of Cancer-Specific Death

Shorter RCC Recurrence Time Ups Risk of Cancer-Specific Death

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The risk of cancer-specific death at 1 year was 48% and 23% for patients whose disease recurred at 3 months and 3 years, respectively.

Renal Mass Biopsy Underused in U.S.

Renal Mass Biopsy Underused in U.S.

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The proportion of patients undergoing the procedure has stayed at 6%-7% annually.

Study Identifies RCC Predictors

Study Identifies RCC Predictors

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Larger tumor size, male sex, and higher nephrometry score indicate a greater likelihood that a renal mass is malignant, researchers report.

Scoring System May ID Best Candidates for SRM Active Surveillance

Scoring System May ID Best Candidates for SRM Active Surveillance

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The DISSRM score may be an easy-to-calculate surrogate for competing risk mortality.

Predictors of Post-Nephrectomy Readmission ID'd

Predictors of Post-Nephrectomy Readmission ID'd

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Open procedures, preoperative dialysis, and higher ASA score were significant predictors of readmission after radical nephrectomy.

RCC Surveillance Guidelines Need Improvement

RCC Surveillance Guidelines Need Improvement

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Following guidelines from the AUA and NCCN would miss many cases of disease recurrence following surgery, study suggests.

Lower SES Predicts More Advanced Renal Cancer at Diagnosis

Lower SES Predicts More Advanced Renal Cancer at Diagnosis

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Patients of lower socioeconomic status present with larger tumors, higher T stage, positive lymph nodes.

Statins May Improve RCC Surgery Outcomes

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Statin use decreases the risk of disease progression after surgery for localized RCC.

Statins Reduce Kidney Cancer Progression

Statins Reduce Kidney Cancer Progression

Reduced risk of progression of localized renal cell carcinoma observed in patients on statins.

Cryoablation Offers Long-Term RCC Control

Cryoablation Offers Long-Term RCC Control

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The 5-year disease-free and cancer-specific survival rates were 94.7% and 100%, respectively.

Radiofrequency Ablation May Be a Valid Approach for RCC

Radiofrequency Ablation May Be a Valid Approach for RCC

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Study shows it can provide durable oncologic control with a low risk of tumor recurrence.

Elevated CKD Risk May Remain Despite Partial Nephrectomy

Elevated CKD Risk May Remain Despite Partial Nephrectomy

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Risk is not eliminated if patients have risk factors for chronic kidney disease, such as hypertension and diabetes.

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