Kidney Cancer

Broad-spectrum Antibiotics May Reduce Survival in mRCC

Broad-spectrum Antibiotics May Reduce Survival in mRCC

The researchers found that patients treated with ABT had decreased progression-free survival compared with those not receiving ATB.

Biologics Combo Shows Promise As First-Line mRCC Therapy

Biologics Combo Shows Promise As First-Line mRCC Therapy

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In a phase 2 trial, atezolizumab plus bevacizumab improved PFS versus sunitinib in patients with renal cell carcinoma expressing PD-L1.

Sunitinib Dose Escalation May Benefit mRCC Patients

Sunitinib Dose Escalation May Benefit mRCC Patients

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Added progression-free survival and prolonged overall survival possible, according to investigators.

Kidney Cancer Brain Metastases Not On the Rise

Kidney Cancer Brain Metastases Not On the Rise

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Researchers develop a model to predict which patients are more likely to harbor brain metastases at cancer diagnosis.

Single RCC Bone Metastasis Predicts Better Survival

Single RCC Bone Metastasis Predicts Better Survival

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Bone surgery should be considered in patients with solitary bone metastasis and no concomitant visceral metastases, according to investigators.

Metabolic Profiles May Distinguish RCC From Benign Masses

Metabolic Profiles May Distinguish RCC From Benign Masses

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In a pilot study, metabolomic analyses of serum and urine showed a high level of predictive ability.

Guidelines Issued for Managing Small Renal Masses

Guidelines Issued for Managing Small Renal Masses

All patients with an SRM should be considered for a biopsy when the results may alter management.

Benign Disease Found in 14% of PN Cases

Benign Disease Found in 14% of PN Cases

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The most common types of benign pathology were oncocytoma, angiomyolipoma, and complex cysts.

Office-Based Renal Mass Biopsy Safe

Office-Based Renal Mass Biopsy Safe

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In a study, only 3 of 108 patients experienced complications, all of which were minor and required no hospitalization or further intervention.

RCC Adjuvant Therapy: Calculating Value

RCC Adjuvant Therapy: Calculating Value

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Adjuvant treatments for RCC must be prioritized by physicians because ultimately value is determined by how medicine is practiced.

Robotic Nephrectomy for Localized RCC On The Rise

Robotic Nephrectomy for Localized RCC On The Rise

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In 2013, nearly one third of all minimally invasive radical nephrectomies were performed with robotic assistance.

Study: Older Age Should Not Preclude Partial Nephrectomy

Study: Older Age Should Not Preclude Partial Nephrectomy

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Partial and radical nephrectomy were associated with similar cancer-specific and overall survival in elderly patients.

CB-839 Drug Promising for Clear Cell, Papillary Renal Cell Cancer

CB-839 Drug Promising for Clear Cell, Papillary Renal Cell Cancer

In the 15 patients in the study, the dual treatment controlled tumors in 93% of the patients, who had either clear cell or papillary renal cell cancer.

Age at Cancer Diagnosis Predicts Cardiac Risk

Age at Cancer Diagnosis Predicts Cardiac Risk

Cancer patients diagnosed in their teens had a more than 4-fold higher risk of death from cardiac disease than patients who didn't have cancer.

Robotic Partial Nephrectomy Offers Better Morbidity Than Laparoscopic

Robotic Partial Nephrectomy Offers Better Morbidity Than Laparoscopic

Robotic partial nephrectomy confers a superior morbidity profile compared to laparoscopic partial nephrectomy.

Renal-Cell Cancer Disease-Free Survival Up With Sunitinib

Renal-Cell Cancer Disease-Free Survival Up With Sunitinib

Among patients with clear-cell renal-cell carcinoma at high risk for tumor recurrence, the duration of disease-free survival was significantly longer in the sunitinib group.

Obesity Ups Risk for Secondary Primary Cancers in Men

Obesity Ups Risk for Secondary Primary Cancers in Men

Prediagnosis obesity is a risk factor for overall and individual secondary primary cancers.

Cabozantinib Superior as Front-Line Therapy for Advanced RCC

Cabozantinib Superior as Front-Line Therapy for Advanced RCC

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Use of the drug is associated with significantly longer progression-free survival compared with suninitib in treatment-naïve patients.

TKI Dose Escalation After mRCC Progression Beneficial

TKI Dose Escalation After mRCC Progression Beneficial

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In a small study, researchers observed a decrease in tumor burden and extended duration of therapy.

Partial Nephrectomy Use Increasing

Partial Nephrectomy Use Increasing

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Study of US veterans reveals, however, that the procedure is being used less in subgroups who might benefit the most.

Immunotherapy Increasingly Used in Cancer Care

Immunotherapy Increasingly Used in Cancer Care

Immunotherapy treatments for patients with bladder cancer, head and neck cancer, Hodgkin's lymphoma, and kidney cancer, is useful against malignancy, according to Cancer Progress Report.

Data Support Biopsy Before Renal Cryo

Data Support Biopsy Before Renal Cryo

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The recurrence group had significantly larger tumors than the no-recurrence group.

Higher Complication Rate Found With Open Partial Nephrectomy

Higher Complication Rate Found With Open Partial Nephrectomy

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Open partial nephrectomy had a significantly higher rate of complications.

High BMI Predicts Improved RCC Patient Survival

High BMI Predicts Improved RCC Patient Survival

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Paradoxical association could be related to an altered fatty acid pathway.

Slimmer People Have Lower Risks of Kidney, Other Cancers

Slimmer People Have Lower Risks of Kidney, Other Cancers

International committee finds slimmer individuals less likely to develop variety of malignancies.

Robotic, Open PN Similarly Effective for Endophytic Kidney Tumors

Robotic, Open PN Similarly Effective for Endophytic Kidney Tumors

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Robotic surgery may offer some benefits, such as shorter hospital stay and less blood loss.

Kidney Cancer Risk Linked to Metalworking Fluids

Kidney Cancer Risk Linked to Metalworking Fluids

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Mean exposure of 18.80 mg/m3 per year was associated with a significant 11% increased risk among white men.

Active Surveillance Possible Before Treatment in mRCC

Active Surveillance Possible Before Treatment in mRCC

Some metastatic RCC patients may safely undergo surveillance prior to starting systematic therapy.

Metabolic Factors Linked to RCC Treatment Resistance

Metabolic Factors Linked to RCC Treatment Resistance

Research results provide potential new targets for combination therapy regimens.

Aspirin Does Not Hike Kidney Surgery Bleeding Complications

Aspirin Does Not Hike Kidney Surgery Bleeding Complications

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Study finds no increased risk of overall complications in patients undergoing robotic partial nephrectomy.

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