Kidney Cancer

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Renal, Urothelial Cancers Linked to Lower Kidney Function

Jody A. Charnow May 22, 2012

Lower renal function is associated with an increased independent risk for renal and urothelial cancer, according to data presented at the American Urological Association 2012 annual meeting.

Survival Better with Partial Nephrectomy

Stephan Cho May 19, 2012

Partial nephrectomy (PN) is associated with better overall survival compared with radical nephrectomy (RN) for patients with early-stage kidney cancer, researchers reported at the American Urological Association 2012 annual meeting.

Drug Cleared for Treating Renal Angiomyolipomas

Stephan Cho April 27, 2012

The FDA has approved everolimus (Afinitor) for the treatment of renal angiomyolipomas and tuberous sclerosis complex (TSC) in adult kidney tumor patients who do not require immediate surgery.

Active Surveillance May Be Okay for Some Men with Metastatic Kidney Cancer

John Schieszer April 27, 2012

Active surveillance may be appropriate for up to 10% of patients with metastatic kidney cancer, according to researchers at the Cleveland Clinic.

Preventing Needless Nephrectomies Possible

John Schieszer March 29, 2012

SAN FRANCISCO—Percutaneous image-guided renal mass biopsy (RMB) combined with immunohistochemical (IHC) results can accurately distinguish between benign and malignant tumors, a finding that could help prevent unnecessary nephrectomies, researchers reported at the 37th Annual Scientific Meeting of the Society of Interventional Radiology.

Image-Guided Ablation a Viable Treatment for Small Renal Tumors

John Schieszer March 26, 2012

SAN FRANCISCO—Image-guided ablation of primary renal cancers smaller than 4.8 cm may be performed with minimal morbidity and produce excellent results in terms of long-term survival, according to a new study presented at the 37th Annual Scientific Meeting of the Society of Interventional Radiology.

RFA Successfully Treats Small Benign Renal Tumors

Jody A. Charnow March 08, 2012

Radiofrequency ablation (RFA) can effectively treat small benign tumors in a single session, and long-term outcomes of RFA for renal tumors depend on tumor size, according to the findings of two studies.

Study: Partial Nephrectomy Complications Mostly Minor

Jody A. Charnow February 26, 2012

PARIS—Nearly one quarter of patients undergoing partial nephrectomy (PN) experience complications, but most are minor, a researcher reported at the 27th Annual Congress of the European Association of Urology.

Partial Nephrectomy Rates Rise, but Disparities Exist

Jody A. Charnow February 26, 2012

PARIS—Partial nephrectomy (PN) rates have increased dramatically, but this surgical approach is underused in certain patient populations, according to data presented at the 27th Annual Congress of the European Association of Urology.

Renal Dysfunction After Radical Nephrectomy Raises Cardiovascular Risks

Jody A. Charnow February 25, 2012

PARIS—Renal dysfunction following radical nephrectomy (RN) for renal cancer is associated with an increased risk of cardiovascular (CV) events and non-cancer-related mortality, Japanese researchers reported at the 27th Annual Congress of the European Association of Urology.

More Tailored Treatments for Kidney Cancer Possible

John Schieszer February 16, 2012

Two newly published studies provide a unique foundation for a more complete understanding of distinct kidney cancer subtypes.

Cryotherapy Can Successfully Treat Small Renal Masses

Nayanah Siva February 14, 2012

LONDON—Cryotherapy can be used to treat small renal tumors or masses successfully with relatively low rates of complications and recurrence, a urologist skilled in the technique told attendees at the Renal and Bladder Cancer 3rd National conference here.

Immunotherapy May Improve mRCC Outcomes

John Schieszer February 08, 2012

SAN FRANCISCO—An immunotherapy (AGS-003) in combination with sunitinib may help prolong the lives of men with unfavorable risk, metastatic renal cell carcinoma (mRCC), according to new data from an open-label phase 2 study.

Bisphosphonates May Improve Outcomes in Patients with RCC and Bone Metastases

John Schieszer February 08, 2012

SAN FRANCISCO—Combining a bisphosphonate with sunitinib may improve progression-free survival (PFS) and overall survival (OS) in patients with bone metastases from renal cell carcinoma (RCC), that are treated with sunitinib, according to a multicenter, retrospective study presented at the 2012 Genitourinary Cancer Symposium.

Prior Sunitinib Duration Affects Second-Line RCC Therapy Outcomes

John Schieszer February 07, 2012

SAN FRANCISCO—Prior sunitinib treatment for nine months or longer may be associated with a longer progression-free survival (PFS) in patients with metastatic renal cell carcinoma (RCC) receiving axitinib as second-line treatment, according to a new study presented at the 2012 Genitourinary Cancer Symposium.

Kidney Cancer Tumor Size, Preoperative eGFR Linked

Jody A. Charnow January 30, 2012

Tumor diameter and decreased preoperative estimated glomerular filtration rate (eGFR) are independently correlated in patients undergoing surgery for renal cell carcinoma (RCC), researchers concluded.

Adrenalectomy Rates Remain High in Radical Nephrectomy

Jody A. Charnow January 30, 2012

During a recent 10-year period, the rate of ipsilateral adrenalectomy at the time of radical nephrectomy decreased slightly, a study found.

Kidney Cancer Tied to Red Meat Intake

Jody A. Charnow January 27, 2012

Greater intake of red meat may increase the risk of renal cell carcinoma (RCC).

Radiofrequency Ablation, Partial Nephrectomy for RCC Offer Similar Long-Term Outcomes

Jody A. Charnow January 11, 2012

In appropriately selected patients, radiofrequency ablation (RFA) is an effective minimally invasive treatment for cT1a renal cell carcinoma (RCC) that offers long-term oncologic outcomes comparable to nephron-sparing surgery, data show.

Ultrasound Not Inferior for Sizing Renal Masses

Jody A. Charnow January 06, 2012

Ultrasound imaging works as well as computed tomography (CT) and magnetic resonance imaging (MRI) for evaluating renal mass size, a new study suggests.

On The Forefront

Sickle Cell Trait and Medullary Renal Carcinoma

A 55-year-old Caucasian woman initially presented to one of Cleveland Clinic's regional outpatient urology clinics with gross hematuria and an obstructing right ureteral stone.

Renal Nutrition Update

High Protein Intake May Elevate Levels of Advanced Glycation End Products

Advanced glycation end products (AGEs) are byproducts of non-enzymatic chemical reactions between sugars and amino acids, lipids, or DNA. A wide range of molecules fall into this category.

Commentary

Prostate Cancer Screening: Moving Beyond PSA

The merits of PSA screening have been widely debated due largely to its low specificity for prostate cancer (PCa), especially for high-grade disease.

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Optimal Sequencing of the New Prostate Cancer Drugs: An Interview with E. David Crawford, MD

Several new drugs have become available for treating advanced prostate cancer in the past year and a half. Dr. Crawford talks to Renal & Urology News about the possible ways in which these drugs might be used.