Papillary Renal Cell Cancer Linked to Renal Cysts
Papillary renal cell cancer (RCC) is associated with simple renal cysts (SRCs), new findings from a Finnish study suggest.
Harri Visapää, MD, of Helsinki University Central Hospital and the University of Helsinki, and colleagues studied 482 patients who underwent partial or radical nephrectomy for kidney tumors from 2006 to 2010. SRCs were more prevalent in patients with papillary RCC than those with other types of tumors. Of the 75 patients with papillary RCC, 55 (73%) had SRCs outside the primary tumor compared with 106 (33%) of the 319 patients with clear cell RCC and 18 (38%) of 47 with oncocytoma, the investigators reported online ahead of print in Urologia Internationalis.
In addition, male gender and increasing body mass index (BMI) and age were associated with the presence of SRCs. All obese patients (BMI of 30 kg/m2 or greater) had SRCs.
The researchers acknowledged the lack of control patients without renal neoplasia was a study weakness.