Papillary RCC More Common in African Americans

Racial difference found among patients undergoing robotic partial nephrectomy for renal tumors.
Racial difference found among patients undergoing robotic partial nephrectomy for renal tumors.

Among patients undergoing robotic partial nephrectomy (RPN) for renal tumors, African-American (AA) patients are more likely than non-AA patients to have papillary renal cell carcinoma (RCC), a study found.

Investigators at Cleveland Clinic in Ohio led by Jihad H. Kaouk, MD, examined the possible effects of race on pathologic outcomes and kidney function preservation in patients undergoing RPN. Of 1,005 patients, 84 were AA. The AA and non-AA patients were comparable in age and tumor size (2.7 vs. 3 cm). The proportion of patients with papillary RCC was significant higher in the AA than the non-AA patients (43.3% vs. 19.4%), the researchers reported online in the Journal of Robotic Surgery

After matching AA patients with non-AA counterparts, the preservation of estimated glomerular filtration rate (eGFR) after surgery between the groups was similar (84.3% vs. 85%). On multivariate analysis, AA race, male gender, and low preoperative eGFR predicted papillary RCC. The researchers observed no difference in kidney function recovery after RPN.

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