September 2016 Issue of Renal And Urology News

September 2016 Issue of Renal And Urology News

September 2016 Issue of Renal & Urology News

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Nephrology Cover Articles

High-Dose ESAs Found to Increase Cancer Risk in Dialysis Patients

Average weekly doses greater than 70 µg/week was associated with a 77% increased risk of cancer compared with no ESA exposure.

Intensive BP Control in CKD Improves Survival

Black CKD patients with strict blood pressure control had a 19% lower risk of premature death.

Urology Cover Articles

Active Surveillance Possible Before Treatment in mRCC

Some metastatic RCC patients may safely undergo surveillance prior to starting systematic therapy.

Erectile Dysfunction Linked to Vitamin D Deficiency

The prevalence of ED is 30% higher among men who have vitamin D levels below 20 ng/mL versus those with levels of 30 ng/mL or ...

High-Grade Prostate Cancer Linked to Diabetes Drugs

Men who used the medications prior to radical prostatectomy had 83% greater odds of Gleason 7-10 tumors compared with non-users.

Commentary

Medical Advancements Versus the Status Quo

Medical research inherently seeks to improve approaches to clinical care.

News in Brief

Hypertension May Raise Prostate Cancer Risk

Data from 21 observational studies showed an 8% increased risk of prostate cancer.

Prostate Cancer BCR Risk Not Linked to Statin Use

Over a median follow-up of 70 months, 15% of men studied experienced biochemical recurrence.

Low Hemoglobin Associated With Elevated Risk of CIN

CIN developed in 14.7% of patients with low hemoglobin levels compared with 5% of those with normal levels.

Tight Glycemic Control May Help Diabetic NMIBC Patients

Patients with diabetes had a significant 42% increased risk of recurrence of cancer and 79% increased risk of progression.

Feature

Hepatitis C in CKD: Challenges and Opportunities

The availability of direct-acting antiviral drugs may enable eradication of hepatitis C virus and improve outcomes.

Practice Management

CMS' Chronic Care Management Program: Is It Worth the Effort?

The gross revenue of the CCM program for a physician with 1,742 patients could range from $44,000 if about one-third of the Medicare patients are ...

General News

Cardiac Event Risk in PCa Patients Higher After Radiation Than Surgery

Radiation therapy also is associated with a greater likelihood of fractures.

Robot-Assisted Prostate Surgery Safe, Effective Long Term

Largest Asian series to date shows a 5-year biochemical recurrence-free survival rate of 76.4%.

Metastatic Prostate Cancer Cases Increasing

Research emphasizes the need for nationwide refinements in the prostate cancer screening process.

Parathyroidectomy for SHPT May Reduce PAD Risk

The risk of peripheral arterial disease was 34% lower for end-stage renal disease patients who underwent the procedure.

Uncontrolled Phosphorus Linked to Poor Binder Adherence

In a study, 61% of hemodialysis patients reported accidentally forgetting to take their medication or otherwise skipping doses unintentionally.

PCa Active Surveillance Patients Enjoy Good Quality of Life

Study finds no greater burden from untreated cancer among active surveillance patients.

Race Affects Switch From Prostate Cancer Observation to Active Therapy

Blacks found to be slightly more likely than whites to leave observational management to undergo radiotherapy or surgery.

Robotic, Open Prostate Cancer Surgery Offer Similar Early Results

No significant differences observed in standard oncologic outcomes and quality of life at 12 weeks.

Assisted PD May Be a Safe Alternative to In-Center HD

Assisted peritoneal dialysis and in-center hemodialysis are associated with similar hospitalization rates.

Aspirin Does Not Hike Kidney Surgery Bleeding Complications

Study finds no increased risk of overall complications in patients undergoing robotic partial nephrectomy.

More Intensive Renal Replacement Therapy Possibly Harmful

This approach is associated with lower urine output during the first 7 days of therapy.

Cystatin C Superior for Predicting Death Risk

Cystatin C values are significantly associated with all-cause mortality, whereas creatinine-based estimates are not, study finds.

Glomerulonephritis Raises End-Stage Renal Disease Risk

Data suggest primary GN is more likely than secondary GN to result in end-stage renal disease.

ED Drugs May Not Reduce Prostate Cancer Risk

Prostate cancer was diagnosed in 19.5% of PDE5i users vs 22.7% of nonusers, a statistically insignificant difference.

Hyponatremia Predicts Higher Mortality in Some Cancer Populations

Study characterizes death risk associated with hyponatremia in patients with lymphoma and breast, lung, and colorectal cancer.

Kidney Cancer Risk Linked to Metalworking Fluids

Mean exposure of 18.80 mg/m3 per year was associated with a significant 11% increased risk among white men.

ESA Resistance Linked to Vitamin B6 Treatment

IV administration of vitamin B6 did not improve anemia or abnormal bone metabolism over 6 months.

Radical Local Therapy Offers Mortality Benefit in Very High-Risk PCa

Prostatectomy and radiotherapy with or without ADT reduced prostate cancer-specific and all-cause mortality rates.

Gout Found to Increase Type 2 Diabetes Risk

The effect of gout on type 2 diabetes risk was more profound in women than men.

Robotic, Open PN Similarly Effective for Endophytic Kidney Tumors

Robotic surgery may offer some benefits, such as shorter hospital stay and less blood loss.

Hyperkalemia Increases Mortality Risk

In a large study, high potassium levels were associated with a significant 24% increased risk of death compared with normal levels.

Intermediate HDL Cholesterol Levels Linked With Better Survival

Researchers found a U-shaped relationship between HDL cholesterol and premature death across all levels of kidney function.

Infection Occurs in One Fourth of Radical Cystectomy Patients

Patients who underwent a radical cystectomy (RC) developed postoperative infection after a median of 13 days.

Proton Pump Inhibitors May Up CKD Risk

PPI use was associated with 10% increased odds of CKD and 76% increased odds of death.

Sexual Problems Linked to 5ARI Use for BPH

Use of 5ARIs for BPH was associated with a statistically significant increased, pooled relative risk for sexual dysfunction.

Bacteremia Often Caused by TURP

Researchers' results showed that the presence of a urinary catheter and recent antibiotic use were associated with increased odds of intra-operative bacteremia.

Higher Complication Rate Found With Open Partial Nephrectomy

Open partial nephrectomy had a significantly higher rate of complications.

Data Support Biopsy Before Renal Cryo

The recurrence group had significantly larger tumors than the no-recurrence group.

Metastatic PCa Is On the Rise

Between 2007 to 2013, the incidence of metastatic PCa increased by 7.1% annually.

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