September 2014 Issue of Renal And Urology News

September 2014 Issue of Renal And Urology News

September 2014

Nephrology Cover Articles

Renal Failure Clusters in Families

The finding is from a study of more than 5 million Norwegians.

More Blood Pressure (BP) Control Not Always Best in Hypertension

An SBP target of about 120-140 rather than below 140 mm Hg may be more beneficial.

Dual Kidney Transplant (DKT) May Improve Kidney Use

Graft survival was similar to that seen in concurrent single SCD kidney recipients

Urology Cover Articles

Novel Urine Prostate Cancer Test Shows Promise

It is more sensitive than digital rectal examination and transrectal ultrasound and more specific than PSA and PSA density, researchers report.

Focal Prostate Cancer Therapy Safe, Feasible

In a study, none of the 62 men who had the treatment experienced erectile dysfunction or urinary incontinence.

Acute Kidney Injury Linked to Atypical Antipsychotic Drugs

Seniors taking atypical antipsychotic drugs are at higher risk of acute kidney injury.

Commentary

The Ebola Threat: Why Not an Outbreak Here?

The separation of continents no longer provides a secure buffer against the spread of communicable diseases from far-flung places.

News in Brief

Partial Nephrectomy Superior Despite Kidney Tumor Size

Renal function is preserved better compared with radical nephrectomy even when tumors are larger than the traditional 4 cm cutoff.

Is allowing patients direct access to lab results a good idea?

A ruling from the HHS took effect allowing patients direct access to medical laboratory results.

Prostate Cancer Patients Face Higher Risk of Second Malignancies

Study reveals a 2-fold greater likelihood of primary kidney and bladder cancer compared with men in the general population.

Hemodialysis Antibiotic Lock Cuts Infection Risk

A solution of gentamicin and citrate decreased the likelihood of catheter-related infections and mortality.

Diabetic Nephropathy Linked to Hypothyroidism

Researchers find an independent association in a study of Japanese patients with type 2 diabetes.

Two-Drug Pill Okayed for Treating Diabetes

Invokamet combines in a single table canagliflozin and metformin.

BRCA2 Mutation Ups Prostate Cancer Death Risk

In a study, the 12-year prostate cancer survival rate was 61.8% for men with the mutation versus 94.3% for those without it.

Feature

Shared Decision Making in Managing Idiopathic and Neurogenic OAB

Communicating effectively about appropriate options and eliciting patient input for overactive bladder (OAB) can improve outcomes.

General News

Degree of Hydronephrosis Predicts Urothelial Carcinoma (UTUC) Outcomes

Moderate to severe hydronephrosis is associated with worse cancer-specific survival in patients with upper tract urothelial carcinoma.

Substance Abuse May Worsen Advanced Prostate Cancer Outcomes

Patients with substance use disorder are more likely to be hospitalized and to make emergency department visits.

Alcohol May Protect Kidney Function in Men

Heavy and binge drinking found to significantly decrease the likelihood of renal dysfunction.

Visceral Fat Area Predicts Kidney Cancer Subtype

Increased abdominal adiposity is associated with a greater likelihood of clear-cell renal cell carcinoma.

Obesity Ups Bladder, Kidney Cancer Risk in Men

As body mass index increases, so does the risk of kidney and bladder cancers in men and stomach, ovarian, and colon cancers in women.

Advanced Kidney Disease (CKD) Linked to Worse Post-Bypass Outcomes

Severe CKD raised the risk of in-hospital death after coronary artery bypass grafting surgery.

Home Hemodialysis (HHD) Has Benefits, Disadvantages

The risk of hospitalization for cardiovascular causes is lower, but the risk for infection-related hospitalization is higher.

End-Stage Renal Disease (ESRD) Risk Lower with Partial Nephrectomy

Researchers find a greater than 50% reduction in end-stage renal disease risk compared with radical nephrectomy.

Advanced Prostate Cancer Linked to Low Melatonin

Urinary levels of a melatonin metabolite below the median were associated with a 4-fold increased risk versus levels above the median.

Post-Brachytherapy Erectile Function Preserved in Most Men

At 5 years after seed implantation, 59% prostate cancer patients had preserved erectile function.

Blood Pressure Increases Along with Sodium Intake

The association is most pronounced in hypertensives, consumers of high-sodium diets, and older individuals.

MRI Highly Accurate in Detecting Significant Prostate Cancer

Diffusion-weighted technique found to have a sensitivity and specificity of 89%-91% and 77%-81%, respectively.

Stents May Help Some Renal Artery Stenosis (RAS) Patients

Stenting may benefit patients with renal artery stenosis who have historically been excluded from modern clinical trials.

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