October 2010 Issue of Renal And Urology News

October 2010 Issue of Renal And Urology News

October 2010

Cover Articles

Caesarean Births Lower Prolapse Risk

TORONTO—Caesarean deliveries significantly reduce the risk of prolapse compared with vaginal delivery, according to a data presented at the joint International Continence Society—International Urogynecological Association ...

Older Drugs May Be Okay For VRE UTIs

BOSTON—Clinicians may want to rethink the antibiotics they prescribe for vancomycin-resistant Enterococcus (VRE) urinary tract infections (UTIs).

Recurrent UTIs After Renal Transplants

BOSTON—Older age, female gender, and delayed graft function are among the independent risk factors for recurrent urinary tract infections (UTIs) among renal transplant recipients.

Commentary

HGPIN: Precursor, Marker, or Meaningless?

The ongoing controversy as to whether premalignant, prostatic lesions are associated with increase risk of developing cancer.

News in Brief

Prostate Biopsy Can Impair Voiding, Erectile Function

Men who undergo prostate biopsy should be informed that the procedure can cause impaired voiding and transient erectile dysfunction, concluded Tobias Klein, MD, and colleagues ...

Lower BP in CKD Helps Only When Proteinuria is Present

Intensive BP control is no better than standard BP control at protecting against progression of kidney disease among African Americans with CKD, except perhaps if ...

Heavy Smoking Reduces Sperm Proteins Needed for Fertility

Men who smoke more than 20 cigarettes a day have a 14% lower concentration of the protamine P2 than their nonsmoking counterparts, according to a ...

Urolithiasis Cases Up at Pediatric Hospitals

The number of children with urolithiasis seen across 42 U.S. pediatric hospitals rose from 125 in 1999 to 1,398 in 2008, according to a recent ...

Screening Lapses Worsen Prostate Cancer Diagnosis for Blacks

Black men are more likely than white men to have had a longer PSA screening interval before a prostate cancer (PCa) diagnosis, and are more ...

Steroids Do Not Stop Post-Transplant ARF

Administering corticosteroids to deceased, heart-beating kidney donors at least three hours before organ harvesting to reduce inflammation does not reduce the incidence or duration of ...

Feature

Have MD, Will Travel: Locum Tenens Docs Today

Fed up with the frustrations of private practice, some urologists and nephrologists have chosen the life of an itinerant professional.

FDA News

Drug for Chronic Refractory Gout Approved

Savient Pharmaceuticals, Inc., of East Brunswick, N.J., has received FDA clearance to market Krystexxa (pegloticase) as a treatment for chronic gout in adult patients refractory ...

Withdrawal of Approval for Midodrine Proposed

The FDA has proposed withdrawing approval of midodrine, a drug used to treat orthostatic hypotension, because required post-approval studies that verify the clinical benefit of ...

Brand Name for Epoprostenol for Injection Okayed

The FDA has approved the brand name for commercially available Veletri (epoprostenol for injection) for pulmonary arterial hypertension (PAH).

Legal Issues

Urologist Pays Heavy Price After Discounting Complaints from Annoying Patient

Dr. L, 68, was busy. His urology practice was booming and he felt compelled to shuffle patients in and out quickly. As a sole practitioner ...

Malpractice News

Tennessee Considers Changes To Medical Malpractice Laws

The Tennessee legislature is considering two bills intended to reform medical malpractice claims.

Nevada Supreme Court To Reexamine Damage Caps

Like Illinois and Georgia before it, the state Supreme Court of Nevada is being asked to decide whether limits on malpractice awards are constitutional.

Taking Responsiblity Found To Reduce Malpractice Suits

A recently published study in Annals of Internal Medicine (2010;153:213-221) shows that taking responsibility for medical errors and apologizing to patients leads to fewer lawsuits.

Renal Nutrition Update

Chewing Gum Could Aid in Phosphorus Control

Chitosan gum could offer dialysis patients an inexpensive way to control phosphorus nonsystemically without adding to their daily pill burden.

Your Money

Short Selling Can Result in Big Profits

Plenty of fund investors are frustrated. During the three years ending August 16, the S&P 500 lost 7.4% annually and most funds sank into the ...

General News

Living Kidney Donor Outcomes Vary by Race

Black and Hispanic living kidney donors are at increased relative risk for hypertension, diabetes requiring drug therapy, and CKD compared with their white counterparts, according ...

Acute Graft Pyelonephritis Does Not Adversely Affect Long-Term Transplant Outcomes

Acute graft pyelonephritis (AGPN) in renal transplant recipients does not impair long-term graft function, according to Spanish researchers.

Potential Gene Biomarkers for OAB Identified

TORONTO—An analysis of gene-expression patterns in women with overactive bladder (OAB) may point the way to possible new biomarkers for the condition.

ED Drugs Can Ease Post-Op Urinary Incontinence

TORONTO—Use of an oral phosphodiesterase type-5 inhibitor (PDE5i) significantly reduces urinary incontinence after radical prostatectomy (RP), according to data presented at the joint annual meeting ...

Kidney Waiting List Has More Nonrenal Transplant Patients

Kidney transplant candidates who are placed on a waiting list after receiving a nonrenal solid-organ transplant make up a significant and more rapidly growing cohort ...

More Deaths in First Year After PD-to-HD Switch

Patients with end-stage renal disease (ESRD) who convert to hemodialysis (HD) after failing treatment with peritoneal dialysis (PD) may be at higher death risk in ...

Cranberries May Relieve LUTS in Men

Dried cranberries may ease lower urinary tract symptoms (LUTS) in men, new findings suggest.

Initial PSA Value After Salvage Cryoablation Predictive

Initial PSA levels following salvage cryoabation in prostate cancer patients who failed radiation therapy may predict the likelihood of long-term biochemical progression, researchers found.

Digoxin Increases Mortality Risk in Hemodialysis Patients

Digoxin use among patients who are on hemodialysis (HD) may increase their risk of death, especially if they have low predialysis potassium levels, a study ...

Kidney Transplant Centers Embracing Influenza Vaccination

Transplant programs in the United States have increasingly embraced influenza vaccination guidelines established by the Centers for Disease Control and Prevention (CDC), researchers concluded.

PSA at Age 60 Predicts Prostate Cancer Death Risk

PSA levels measured at age 60 predict a man's lifetime risk of metastasis and death from prostate cancer (PCa), according to a study published online ...

Why a DASH-Style Diet May Prevent Kidney Stones

A diet rich in fruits and vegetables, moderate in low-fat dairy products, and low in animal protein may reduce the risk of kidney stones by ...

Brachytherapy Alone a Viable Alternative

Study reveals acceptable outcomes in men with clinically localized intermediate-risk prostate cancer.

Polypropylene Sling May Improve Stress Urinary Incontinence

Two years post-op, 87% of patients said they were 'satisfied' or 'very satisfied' with the results.

Post-Op UI Therapy Sessions Not Better

Men with urinary incontinence after prostate surgery do just as well with self-teaching approaches.

UTI Risk in Spinal Injury Reduced by New Catheter

Hydrophilic-coated catheter shorted time to first UTI in patients with acute spinal cord injuries.

Healthy Habits May Improve Urinary, Sexual Function

SAN FRANCISCO—Healthy lifestyle choices, such as not smoking and exercising regularly, may significantly impact urinary and sexual function, two studies suggest.

Selenium May Protect Against Bladder Cancer

High selenium intake may have a protective effect against bladder cancer, mainly among women, according to a recent meta-analysis.

Multiple Arteries Do Not Worsen Transplant Outcomes

VANCOUVER, British Columbia—Transplantation of kidneys with single or multiple arteries results in similar long-term outcomes, according to new study presented at The Transplantation Society's 2010 ...

Clinicians React to FDA's Gadolinium Warnings

The rate at which patients with renal disease are undergoing magnetic resonance (MR) studies using gadolinium-based contrast agents decreased dramatically since 2006.

New Insights into Donor-Recipient Age Matching

VANCOUVER, British Columbia—Findings from two large studies presented at The Transplantation Congress in Vancouver provide new insights into the practice of matching donors and recipients ...

Post-Transplant Cinacalcet May Be An Option

Cinacalcet may be useful for treating hyperparathyroidism after renal transplantation, new findings suggest.

NAC May Treat Anemia in HD Patients, Study Shows

Oral N-acetylcysteine (NAC) supplementation may be a promising adjuvant treatment for uremic anemia and oxidative stress in hemodialysis (HD) patients, researchers say.

Ureteral Stone Size Predictable, Data Show

The degree of hydronephrosis may predict ureteral stone size, according to a study published in the American Journal of Emergency Medicine (2010;28:813-816).

Gen-Probe Seeks Approval for Prostate Cancer Test

Gen-Probe has submitted a Premarket Approval Application (PMA) to the FDA for its PCA3 assay (Progensa), which may help determine the need for repeat prostate ...

Drug for Cushing's Disease Shows Efficacy in Phase 3 Trial

An investigational drug called pasireotide is effective at reducing cortisol levels in patients with Cushing's disease, according to the results of a phase 3 trial.

Men at Higher Risk for AUR After BoNTA Treatment

Researchers in Taiwan have identified risk factors for adverse events (AEs) from intravesical injections of botulinum toxin A (BoNTA) for refractory idiopathic detrusor overactivity (IDO).

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