November 2013 Issue of Renal And Urology News

November 2013 Issue of Renal And Urology News

November 2013

Cover Articles

Expulsive Therapy for Stones May Cut Costs

Patients missed fewer days of work after undergoing medical expulsive therapy than after having early endoscopic stone removal.

Reduced Kidney Function Hikes Cancer Death Risk

The highest risks of cancer-related mortality were in individuals with urinary tract and breast cancers.

Post-Radiation Erectile Dysfunction Linked to Comorbidities

The risk of ED is increased by about 75% if hypertension, diabetes, and hyperlipidemia are present concomitantly.

New Clues to Optimizing mCRPC Regimens

Data suggest that sipuleucel-T is effective despite comcomitant abiraterone treatment and cabazitaxel may have advantages over abiraterone for second-line therapy.

Dialysis Patients Hospitalized on Weekends Have Worse Outcomes

They have a higher inpatient mortality risk and longer lengths of stay compared with those admitted on weekdays.

Dialysis Patient Bloodstream Infections Linked to CVCs

Vascular access-related bloodstream infections were 13 times more likely to develop in patients with than without central venous catheters.

Commentary

Medical Research and the Federal Shutdown

After the end of 16-day federal shutdown in October, media headlines touted the financial impact on America and the cost of restarting the government.

Men's Health Update

Erectile Dysfunction Linked to Elevated Uric Acid

Researchers found the association in men presenting with suspected coronary artery disease.

Low Testosterone Associated with Increased Dementia Risk

Low bioavailable testosterone significantly increased the risk in men aged 80 and older.

High-Deductible Health Plans Affect Men More

A new study reveals a sex-specific response to high-deductible health plans (HDHP).

Bariatric Surgery Does Not Improve Male Infertility

The effect of obesity on male infertility has been well established.

Divorce Hits Men Hard Medically, Psychologically

Divorce can have a significant impact on a man's biological, psychological, and social health.

News in Brief

CKD On the Rise in Individuals Aged 80+

Efforts to address chronic kidney disease among individuals aged 80 years and older may be necessary.

New Device Improves Urine Flow in BPH

The FDA has approved the first permanent implant to relieve low or blocked urine flow in men aged 50 years and older with BPH.

Citrus Component Thwarts Kidney Cysts

The dietary flavonoid naringenin has been found to regulate the PKD2 protein responsible for polycystic kidney disease.

Kidney Function Deteriorates Long After Childhood Cancer

Survivors of childhood cancer are at risk for premature chronic renal failure as their glomerular function continues to deteriorate.

Living Donor Comorbidities Are Increasing, Study Finds

Complications and hospital lengths of stay after kidney donation declined from 10.1% and a mean 3.7 days, respectively.

Feature

Bladder Cancer in the Elderly: Balancing Disease and Surgical Risk

Elderly patients face greater perioperative risks and postoperative mortality, so careful selection of surgical candidates is imperative.

Renal Nutrition Update

Adequate Vitamin D Important for Immunologic Regulation

Vitamin D is often recognized for its impact on bone metabolism, but it is also an important regulator of immune function.

General News

Coffee May Cut Risk of Prostate Cancer Recurrence, Progression

Drinking one or more cups per day reduces the risk by 56% compared with drinking one or fewer cups per week.

ATP Nixed for Assessing Urinary Infection

Study results underscore the need for additional research to find other surrogate markers of urinary infection.

Study: 24-Hour Urine Collection Underused

The test was ordered for only about 8% of patients at high risk for urinary stone recurrence.

High-Risk Prostate Tumors Not All the Same

Gleason 8 tumors have a substantially better prognosis after radical surgery than Gleason 9 and 10 tumors.

UTI Risk Unaffected by Catheter Type

Total weeks of self-reported UTI in children with spina bifida were similar with hydrophilic single-use and multi-use PVC catheters.

Antimicrobial Under-Dosing Common in CVVHD

Study finds that 22% of patients did not have the right dose of antibiotics during their time on continuous venovenous hemodialysis.

Repeat BTXA Injections Okay for Non-Neurogenic OAB

Repeat injections of onabotulinumtoxinA (BTXA) appear to benefit patients with non-neurogenic overactive bladder.

High BMI Increases IgA Nephropathy Renal Risks

Overweight or obesity increased hypertension frequency, proteinuria level, and severity of some renal lesions at diagnosis, placing patients at higher risk for dialysis or death.

Women's Phosphorus Levels Affected by Estrogen

Phosphorus levels are lower in postmenopausal women on estrogen replacement therapy.

Belatacept's Renal Transplant Benefits Persist Long-Term

Even after five years on the drug, patients continue to have improved renal function compared with patients receiving cyclosporine A.

Data Point to Nocturia-Hypogonadism Link

Desmopressin appears to reduce nocturia and other LUTS while also significantly increasing testosterone levels in late-onset hypogonadism.

Dyslipidemia May Raise Stone Risk

Low HDL or high triglyceride levels were associated with significantly higher urinary sodium, oxalate, and uric acid levels, as well as lower urinary pH.

High BMI Predicts Adverse Transplant Outcomes

High risker of biopsy-proven acute rejection and death-censored graft failure observed in patients with a BMI of 35 kg/m2 or greater.

Hemodialysis Patients Suffering Fewer Hip Fractures

Trend may be due in part to changes in the management of bone mineral disease, researchers speculate.

Role of Testosterone in Heart Risk Unclear

Men with low testosterone levels may be at slightly increased risk of developing or dying from cardiovascular disease.

New AUA/ASTRO Guideline Addresses PCa Radiotherapy

The guideline recommends that patients with adverse pathologic findings at prostatectomy should be offered adjuvant radiotherapy.

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