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November 2009 Issue of Renal And Urology News

November 2009 Issue of Renal And Urology News

Cover Articles

Botulinum Toxin Injections Ease Refractory Incontinence

Four weeks after treatment, 51% of subjects had complete continence.
 

Minimally Invasive Vs. Open Radical Prostatectomy for Prostate Cancer

Minimally-invasive surgery may be more likely to result in incontinence and erectile dysfunction.
 

Ascorbic Acid May Aid Anemia Management

Ascorbic acid may be effective in managing anemia in hemodialysis (HD) patients, according to a recent meta-analysis by Canadian investigators.
 

Commentary

A More Rational Approach To Renal Mass Surgery

In the absence of level I evidence, physician treatment recommendations are subject not only to the objective (interpretations of the cohort literature and practice guidelines) ...
 

From Cleveland Clinic

Bioartificial Kidney Meeting Research Milestones

A pioneering implantable artificial kidney developed jointly by teams of researchers at Cleveland Clinic, the University of California at San Francisco, and the University of ...
 

Neoadjuvant VEGF-Targeted Therapy in Renal Cell Carcinoma

Recent therapeutic advances in metastatic renal cell carcinoma (RCC) have included agents targeted against vascular endothelial growth factor (VEGF).
 

News in Brief

Drug Therapy for Stones Underused in Emergency Departments

Medical expulsive therapy (MET) for urinary stones in American emergency departments is underused despite evidence of its safety and efficacy, investigators have concluded.
 

Warfarin May Raise Stroke Risk in ESRD Patients

Warfarin use in patients with both end-stage renal disease (ESRD) and atrial fibrillation are at increased risk for stroke, data suggest. It is not associated ...
 

Severe Lower Urinary Tract System Linked to Obesity

A study of 602 Korean men with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia found that those with a waist circumference greater ...
 

Megestrol May Improve Weight in Dialysis Patients

A pilot study showed that megastrol may help improve weight and ability to exercise in dialysis patients, according to a report in the Journal of ...
 

Coronary Artery Calcification Is Common Among Stage 3 CKD Patients

Coronary artery calcification (CAC) is common among individuals with stage 3 CKD, data show.
 

Niacinamide Helps Lower Phosphorus

In an eight-week study of 15 patients, oral niacinamide added to standard phosphorus-lowering therapies resulted in a modest yet significant reduction in plasma phosphorus levels ...
 

Tamsulosin Eases Voiding Symptoms in Women

Tamsulosin may be an effective treatment for women with voiding dysfunction due to functional bladder outlet obstruction (BOO).
 

Feature

Patients, Doctors Embrace the Web

Patients seek medical information and physicians launch web sites to educate patients and advertise.
 

FDA News

New Medication Approved for Treated Advanced Renal Cell Carcinoma

The FDA has approved Votrient (pazopanib) for the treatment of advanced renal cell carcinomia (RCC).
 

Colchicine Formulation Cleared for Preventing Gout Flares

Colcrys, a new colchicine formulation, has received marketing clearance for the prevention of gout flares.
 

Telmisartan Okayed for Cardiovascular Risk Reduction

Boehringer Ingelheim Pharmaceuticals has received approval for a new indication for its angiotensin II receptor blocker Micardis (telmisartan).
 

Lithostat for Struvite Stones Reintroduced

Lithostat (acetohydroxamic acid), the only urease inhibitor available for urea-splitting urinary infections in association with struvite stones, is available again at pharmacies nationwide, according to ...
 

Institute Is Awarded DoD Grant For Prostate Cancer Drug Research

The U.S. Department of Defense/Prostate Cancer Research Program (DoD/PCRP) has awarded a $1.55 million grant to SRI International, a nonprofit research institute based in Menlo ...
 

Legal Issues

Inadequate Post-Surgery Care Leads to a Lawsuit

Dr. W was in the middle of a well-deserved dinner with his wife and two teenage children when he was interrupted by a call from ...
 

Malpractice News

Certificate of Merit Requirement Overturned

The Washington State Supreme Court has overturned the state's certificate of merit requirement for malpractice suits.
 

Courts to Decide Legitimacy Of Malpractice Award Caps

Four state supreme courts are set to decide whether to do away with caps on non-economic damages in malpractice cases.
 

Medical Errors Linked to Fatigue, Emotional Distress

Internal medicine residents who report higher levels of fatigue and emotional distress also report higher levels of major medical errors, according to a recent study ...
 

Renal Nutrition Update

Appetite May Predict ESRD Outcomes

Researchers have linked poor appetite in hemodialysis patients with various markers of malnutrition.
 

Your Money

The Risks and Rewards of Owning Gold

Investors incur risks when they own precious metals, but the returns can outpace the S&P 500.
 

General News

Coronary Artery Calcification Linked to Vitamin D Deficiency

Study reveals a 23% increased risk with each 10 ng/mL decrease in 25-hydroxyvitamin D concentration.
 

Women Fare Better After Severe Trauma

They are less likely than men to suffer acute renal failure and other complications, researchers say.
 

Flu Vaccine Advised for Transplant Patients

Influenza should be prevented in renal transplant recipients because it can cause allograft rejection.
 

Age at Starting Renal Replacement Therapy Rises in Canada

In 2007, 54% of patients starting renal replacement therapy were aged 65 and older versus 48% in 1998.
 

Female Pelvic Pain Common But Often Underdiagnosed

LISBON—Visceral pelvic pain is a common yet underdiagnosed problem in women, according to an Italian researcher.
 

Vancomycin-Related Renal Toxicity in Children

Pediatric patients who attain higher trough levels of the drug may be at higher risk of kdiney damage.
 

Donor Dopamine Improves Transplant Outcomes

Giving dopamine to brain-dead kidney donors reduces the need for post-transplant dialysis, data show.
 

ESRD Cause Affects Post-Transplant Fracture Risk

DENVER—The risk of fracture during the first five years after a renal transplant may be associated with the underlying cause of a patient's end-stage renal ...
 

Obesity Raises Prehypertensives' Risk

In a study, prehypertensive patients with the highest BMI had a sixfold increased risk of treated end-stage renal disease or CKD-related death.
 

Healthy Diet May Lower Kidney Stone Risk

The protective effect of a DASH-style diet was similar for men and women regardless of age and BMI.
 

Eating Fish May Lower Diabetes Risk

Higher consumption of shellfish, however, was associated with an increased risk, British study shows.
 

High-Grade Prostate Cancer Less Likely in Men with Low Cholesterol

Men with low cholesterol levels have a decreased risk of high-grade prostate cancer, a recently published study suggests.
 

Radiation Is a Viable Option for Invasive Bladder Cancer

Two-year survival is similar to that achieved with cystectomy.
 

End-Stage Renal Disease Risk in Diabetics Tied To Urine IgM

High levels of immunoglobulin M (IgM) in the urine of diabetic patients may predict development of end-stage renal disease (ESRD) and death from cardiovascular disease ...
 

PTNS Provides Sustained Overactive Bladder Relief

Study findings at 12 months showed prolonged significant improvements in objective urinary parameters.
 

Transobturator Sling Improves Treatment of Female Stress Urinary Incontinence

Before surgery, 6% of women tested negative on the cough stress test compared with 98% at 12 months .
 

Donor Size Not An Issue For Children

Adult kidneys were transplanted successfully into very small recipients.
 

Fractures Increase Mortality Risk In Prostate Cancer Patients on ADT

BERLIN—Men with non-metastatic prostate cancer who begin androgen deprivation therapy (ADT) with vertebral fractures at baseline have shorter survival time compared with those free of ...
 

Genetic Data Confirm Bladder Cancer Link to Smoking

Researchers who analyzed genetic data from patients with bladder cancer discovered three common inherited genetic variants, also known as polymorphisms, which are significantly associated with ...
 

BPH Drug May Raise Testosterone

Dutasteride treatment for benign prostatic hyperplasia (BPH) is associated with a significant increase in serum testosterone and a significant decrease in BMI among men with ...
 

Alendronate May Benefit Long-Term Transplant Survivors

DENVER—Anti-resorptive therapy with alendronate may suppress bone turnover in long-term renal transplant survivors even when intact parathyroid hormone (iPTH) is elevated, according to Japanese researchers.
 

A Novel Way to Assess Fracture Risk

Researchers say bone microarchitecture analyses are more accurate than traditional BMD measurements.
 

Fall Risk in Hemodialysis Patients Linked to Vitamin D Metabolite

Subjects with low 25-hydroxyvitamin D levels had weaker quadriceps.
 

Data Support ELRP for Localized Prostate Cancer

Oncologic outcomes of this laparoscopic technique are in line with other approaches, researchers say.
 

Bacteria Interference May Prevent Urinary Tract Infections

A non-pathogenic strain of E. coli lowered the UTI rate in catheterized men with neurogenic bladder.
 

Antibiotic UTI Prophylaxis Slightly Better

It is associated with fewer recurrences than lactobacilli, but it increases antibiotic resistance.
 

Aggressive Prostate Cancer Linked to Bacteria

Trichomonas vaginalis infection associated with a twofold increased risk of advanced prostate cancer
 

Erectile Dysfunction Drugs May Help Treat Cardiac Hypertrophy

PDE-5 inhibitors block one of the enzymes that break down a chemical which stops heart muscle growth.
 

Oral Drug Is An Appropriate Option for Resistant UTIs

In a study, only 3% of ESBL-producing Escherhicia coli isolates were resistant to fosfomycin.
 

Study Links Urinary Symptoms, Erectile Dysfunction to Diabetes

Almost 68% of diabetic Taiwanese men younger than 45 years reported having erectile dysfunction.
 

Study: Adjuvant High-Dose Radiation Safe

Men who received the intensity-modulated radiotherapy treatment immediately after radical surgery for PCa had low rates of toxicity.
 

Prostate Cancer Risk Linked to Creatinine Levels

The highest levels are associated with a twofold increased risk compared with the lowest levels.
 

Prostate-Sparing Cystectomy Is Safe

This approach has oncologic outcomes similar to that of standard cystoprostatectomy, study shows.
 

Drug's Ability to Lower Prostate Cancer Risk Confirmed

In a study, dutasteride had a protective effect regardless of baseline variables known to affect risk.
 

Smoking Increases Risk of Fatal Prostate Cancer

Recent cigarette smoking is associated with an increased risk of fatal prostate cancer, according to a new report.
 

Review articles

How Bundling Could Affect Nephrology Training

Nephrology fellows may gain insight as a result of a new Medicare payment system for dialysis.
 
Popular Topics
Acute Kidney Injury AKI Androgen Deprivation Anemia Benign Prostatic Hyperplasia Bladder Cancer BPH Cardiovascular Disease Chronic Kidney Disease Circumcision CKD CVD Diabetes Dialysis End-stage Renal Disease Hemodialysis Kidney Cancer Overactive Bladder Prostate Cancer Renal Cell Carcinoma Reproductive Medicine Secondary Hyperparathyroidism Transplantation Urinary Incontinence Urology

 

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