May 2016 Issue of Renal And Urology News

May 2016 Issue of Renal And Urology News

Renal & Urology News - May 2016 Issue

Nephrology Cover Articles

Study: Diabetic Nephropathy Underdiagnosed

Diabetic nephropathy lesions may develop prior to the onset of clinical findings.

Urology Cover Articles

Partial Nephrectomy Protects Against ESRD

Nephron-sparing surgery decreased the risk of end-stage renal disease by 60% in select patients.

Penile Sensitivity Unaffected by Newborn Circumcision, Study Finds

New study challenges a view that the foreskin is the most sensitive part of the adult penis.

Pioglitazone Use, Bladder Cancer Linked

Bladder cancer risk increases with longer duration of use.


Clinical Trials in Surgery: A New Paradigm

Randomized clinical trials are often considered the highest level on which medical care should be based.

Expert Q&A

Novel Approaches to Using Radium-223

An interview with Neal Shore, MD

News in Brief

Low Chloride Levels Linked to Adverse Outcomes in Pre-dialysis CKD

Researchers observe an increased risk of a composite outcome of death from any cause and cardiovascular events.

PTH Level Unrelated to Parathyroid Glands' Weight, Blood Flow

Iranian study of hemodialysis patients with secondary hyperparathyroidism finds no significant correlation.

PSA Screening More Likely Among Blacks

The odds of PSA screening were higher among blacks than non-Hispanic whites.

N-Acetylcysteine May Protect Against CIN

N-acetylcysteine patients had significantly decreased odds of contrast-induced nephropathy.

Aminosalicylates Cut PCa Risk in Men with IBD

Researchers found an adjusted 68% decreased risk of prostate cancer in men with IBD who used aminosalicylate.

Fluoroquinolones May Be Unwarranted for High PSA

PSA level declined by an average of 0.68 ng/mL in the treatment group.

Practice Management

HIPAA Disclosure Rules Not As Strict As Widely Believed

Patients' representatives, individuals designated to make medical decisions for them, have equal rights to access information under HIPAA.

General News

Dietary Potassium Restriction in Hemodialysis Patients Questioned

Researchers argue that little evidence exists to support this approach to prevent hyperkalemia.

Ferritin Levels Rising in Hemodialysis Patients

Trend is independent of intravenous iron use and exposure to erythropoiesis-stimulating agents.

Prostate Cancer Risk Lower in Men Who Ejaculate More

The protective effect is strongest for low-risk disease.

Advanced Prostate Cancer May Respond to Bicalutamide-Everolimus Combo

In a small study, 75% of men with castration-resistant prostate cancer experienced a 30% or greater decline in PSA from baseline.

Larger Upper Urinary Tract Tumors Predict Worse Survival

Patients who undergo surgery for tumors larger than 3 cm are more likely to die from their cancer and from all causes, study finds.

Premature Tooth Loss Common Among ESRD Patients

Findings from a small study suggest that periodontal disease may be a relevant contributing factor.

Live-Donor Kidney Transplant Outcomes Worse with Longer CIT

Increased likelihood of delayed graft function and graft loss observed in recipients of kidneys from donors older than 50 years.

Prostatic Artery Embolization May Reduce Nocturia in BPH

Procedure partially blocks blood flow to the gland and appears to ease the need to urinate.

Periodontitis May Up Erectile Dysfunction Risk

Review finds 1.5-3.4 times higher risk of erectile dysfunction among men with periodontitis.

Study: Shorter Radiotherapy Schedule OK for Localized Prostate Cancer

Disease-free survival rates were similar for groups receiving 8.2 weeks of conventional versus 5.6 weeks of hypofractionated radiotherapy.

Prostate Biopsy Rates Fall Following Guideline Updates

The proportion of biopsied men who have complications from the procedure rose from 14% to 18% from 2005 to 2014.

Higher NLR Predicts More Aggressive Kidney Cancer

Elevated neutrophil-to-lymphocyte ratio is associated with larger tumors and greater nuclear grade.

Afatinib Shows Promise for Metastatic Urothelial Carcinoma

Median time to progression or drug discontinuation was 6.6 months in patients with specific genetic alterations, compared with 1.4 months in other patients.

Positive Margins After Partial Nephrectomy Raises Death Risk

Positive surgical margins are associated with a significant 34% increased risk of all-cause mortality.

Higher Animal Protein Intake Ups Diabetes Risk

Researchers suggest that exchanging vegetable protein for animal protein can lower the risk of diabetes.

COPD Raises Mortality Risk in CKD Patients

Likelihood of overall and respiratory-related mortality is increased 41% and 4-fold, respectively.

Optimal PSA Nadir After Prostate Cryoablation Identified

A PSA nadir below 0.4 ng/mL offers the best long-term biochemical progression-free survival, study shows.

Multiple Comorbidities Predict Higher-Risk Prostate Cancer

Prostate cancer patients with 2 or more comorbid diseases are more likely to have their cancer upgraded and up staged at RP.

Short Sleepers Face Higher Risk of Proteinuria, but Not CKD

Short sleep duration is associated with a 47% increased risk of proteinuria, a surrogate marker for kidney disease progression.

Acthar Gel May Be an Option for Nephrotic Syndrome

Athcar gel may be a treatment option for patients with treatment-resistant nephrotic syndrome.

Hospital- vs Community-Acquired AKI

Poor long-term outcomes found even in patients with community-acquired AKI but not hospitalized.

CKD Is a Risk Factor for UTUC

Researchers found elevated incidences of upper tract urothelial carcinoma (UTUC) in patients with CKD.

Weekend Transplant Outcomes Not Worse

Nearly 28% of deceased-donor kidney transplants in the US were performed on the weekends.

Hip Fracture, Mild Prolonged Hyponatremia Linked

Hypontrameia is linked to increased risk of hip fracture in elderly individuals.

Most Gout Inadequately Controlled

Patients with inadequately controlled gout experience lower quality of life and report worse functioning.

AKI After RCC Surgery On the Rise

Nearly 6% of patients who underwent partial or radical nephrectomy between 1998 and 2010 developed AKI.

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