July 2016 Issue of Renal And Urology News

July 2016 Issue of Renal And Urology News

RUN June-July 2016 Cover

Nephrology Cover Articles

Study Challenges Obesity-Chronic Kidney Disease Link

After adjusting for potential confounders and mediators, a large cross-sectional study found no association between obesity and CKD prevalence.

Statins Protect Against Kidney Stones

Use of the lipid-lowering drugs is associated with 43% and 47% decreased odds of new stones in recurrent stone formers and stone naïve patients.

Critically Ill Acute Kidney Injury Patients Benefit From Early RRT

Study demonstrates improved 90-day survival and greater likelihood of recovering renal function.

Urology Cover Articles

Landmark PSA Screening Trial Results Challenged

The PLCO trial's conclusion that routine PSA testing does not affect prostate cancer mortality risk could be wrong.

Prostate Cancer Risk Not Increased With Testosterone Therapy

In fact, some data suggest treatment may reduce prostate cancer incidence and aggressiveness.

Laser 'Dusting' Compares Favorably As Kidney Stone Treatment

Technique could reduce the need for ureteral access sheaths.

Commentary

New Discoveries Provide Insights Into Calciphylaxis

It is unclear to physicians why some patients develop calciphylaxis while others do not.

Expert Q&A

Why SHPT Remains Difficult to Treat

The control of phosphorus is underappreciated, for example.

News in Brief

Hidden Hypercalcemia Common in Hemodialysis Patients

The condition is associated with a death risk similar to that of apparent hypercalcemia.

Surgeons Perform First Penile Transplant in the US

The 15-hour surgery took place in early May.

Drug Cleared for Refractory Advanced Bladder Cancer

Atezolizumab received accelerated FDA approval for patients whose disease has progressed despite platinum-based chemotherapy.

Lupus Nephritis ESRD Has Worse Outcomes

Researchers find an increased risk of death among patients.

Post-RP Radiation Therapy May Raise OAB Risk

De novo OAB — defined as urgency with or without frequency and nocturia — developed in some patients.

Hip Fracture Rate Higher in Non-Dialysis CKD

Patients with non-dialysis chronic kidney disease (CKD) may be at elevated risk for hip fracture, according the Journal of Bone and Mineral Research.

Practice Management

3 Ways Practices Can Improve Collections From Patients

Prompt-pay discounts and payment plans are among the ways practices can improve collections of what patients owe.

General News

Calciphylaxis Risk Factors in Hemodialysis Patients Identified

Researchers linked the condition to warfarin use, diabetes, obesity, recurrent skin trauma, and derangements in mineral metabolism.

Percutaneous Nephrolithotomy Use Increasing

PCNL procedure rate nearly doubles over a 2-decade period, study finds.

New Bladder Cancer Guidelines Released

Recommendations for diagnosing and managing non-muscle invasive bladder cancer promise to allow for more individualized patient care.

ESA Doses Lower Among Dialysis Patients at Higher Elevations

Investigators find that the normalized mean ESA dose decreases as patients' elevation of residence increases.

Niacin's Phosphorus-Lowering Effect Confirmed

Average 6-month serum phosphorus level was significantly lower in CKD patients who received niacin than those who did not (3.4 vs. 4.2 mg/dL).

Higher FGF23 Levels Increase Odds of Respiratory Infection

The study is the first to find a link between FGF23 levels and infection in non-dialysis patients.

Study Independently Validates New Prostate Cancer Grading System

Findings support the use of a 5 grade-group system that more accurately reflects patient risk of adverse outcomes.

High-Grade Prostate Cancer More Likely To Be Found in Sicker Men

New study shows that heavier comorbidity burdens increase the risk of Gleason 7 or higher tumors being found at biopsy.

High PSA Predicts Elevated Risk of Lower Urinary Tract Symptoms

LUTS is 49% more likely to develop in men with a PSA level above 6 ng/mL versus 4 ng/mL or less.

Prostatic Urethral Lift Benefits Confirmed

New data show that the minimally invasive procedure is superior overall to TURP for treating BPH-related lower urinary tract symptoms.

High-Risk Prostate Cancer Linked to Poverty

In a study of African-American radical prostatectomy patients, low income predicted a higher risk of advanced stage or aggressive tumors.

Low-Carb Diet May Curb Adverse Effects of Prostate Cancer ADT

New findings show metabolic changes suggesting that a carbohydrate-restricted diet may improve insulin sensitivity.

Mortality Rate Higher Among Bodybuilders

Reasons are unclear, but use of testosterone and other performance enhance drugs could be a contributing factor.

Salvage Radical Prostatectomy Offers Good Long-Term Outcomes

Minimally invasive surgery is associated with a lower incidence of bladder neck contracture.

Bariatric Surgery May Ease LUTS in Obese Men

Study documents significant improvements in frequency, urgency, and nocturia.

Proposed Regimen May Cut Hypercalcemia Risk in CKD Patients

Paricalcitol-based protocol includes limited use of calcium-based phosphate binders.

When Blood Is Sampled Affects Dialysis Patients' Phosphorus Values

Phosphorus levels are higher when blood specimens are collected after weekends.

High Uric Acid Increases Risk of Non-Fatal Stroke in CKD Patients

Odds of non-fatal stroke are 49% higher in patients in the fourth quartile of uric acid level versus those in the second quartile.

CKD Progression After Acute Kidney Injury Characterized

Male gender, diabetes, and renal function decline at 90 days implicated as risk factors; patients rarely progress to end-stage renal disease.

Smoking May Increase CKD Risk in African Americans

New findings show that current smokers had an 83% higher incidence of rapid renal function decline compared with never smokers.

Kidney Stone Procedures Found Not to Raise CKD Risk

Researchers find an increased risk for elevated serum creatinine, but not chronic kidney disease or all-cause mortality.

Low HRQoL May Increase CV Event Risk in CKD Patients

The researchers found no relationship between poor quality of life and CKD progression.

Low Midlife Fitness May Predict Future CKD

High vs. low fitness levels in midlife lowered CKD risk in later life by 34%.

Sodium Thiosulfate Promising

A recent study suggests that sodium thiosulfate may be an effective treatment for calciphylaxis.

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