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July 2010 Issue of Renal And Urology News

Cover Articles

Improved Survival with RP vs. Radiation

SAN FRANCISCO—Radical prostatectomy (RP) is associated with significantly better intermediate-term survival than radiation treatment among men with clinically localized prostate cancer, data suggest.

BP Lowering Better with a Triple Regimen

NEW YORK—An investigational triple regimen of olmesartan medoxomil (OM), amlodipine besylate (AML), and hydrochlorothiazide (HCTZ) may result in significantly greater mean reductions in BP compared ...

Risk Factors For Male UI Identified

SAN FRANCISCO—Researchers have identified medical conditions that are independently associated with moderate to severe urinary incontinence (UI) in men. These include major depression, hypertension, and ...

News in Brief

Higher Hemoglobin Goals Raise Stroke Risk

A meta-analysis of 27 trials evaluating erythropoiesis-stimulating agent (ESA) treatment in 10,452 CKD patients shows that compared with a lower hemoglobin (Hb) target, higher Hb ...

Pre-RALP MRI Can Improve Surgical Plans

Performing an MRI before a robotic-assisted laparoscopic prostatectomy (RALP) can help urologic surgeons make more informed decisions as to whether to spare the neurovascular bundle ...

Depression Associated with CKD Complications

CKD patients who have been diagnosed with a current major depressive episode is twice as likely as their non-depressed counterparts to be hospitalized, progress to ...

Dietary Calcium May Boost Prostate Cancer Risk

Dietary calcium may raise the risk of prostate cancer among Chinese men, recent study findings suggest.

Nephrosclerosis Prevalence Found to Increase with Age

Researchers have found a strong association between age and nephrosclerosis in healthy adults, and this association is not explained by kidney function and CKD risk ...

Lanthaum Carbonate Better for Phosphorus Absorption

Mean net dietary phosphorus absorption is significantly lower after a single dose of lanthanum carbonate (LC) than after a single dose of sevelamer carbonate (SC), ...

Feature

The Ethics of Discontinuing Dialysis

One practitioner's perceived good deed for a dying patient could be another's definition of homicide.

FDA News

FDA Mulls Application for Prostate Imaging Device

ProUroCare Medical, Inc., of Minneapolis, Minn., has filed a de novo application with the FDA seeking marketing clearance for its prostate mechanical imaging (PMI) device ...

Imaging Agent for Bladder Cancer Okayed

The FDA has approved Cysview (hexaminolevulinate HCl), an optical imaging agent indicated for use in the cystoscopic detection of non-muscle-invasive papillary bladder cancer in patients ...

Marketing Clearance Granted to New Glucose Test Strips

Abbott has received FDA clearance to market FreeStyle Lite glucose test strips. The test strips minimize interference during blood glucose testing and are designed to ...

Over the Counter Pain Relief Patches Introduced

Hisamitsu Pharmaceutical, which has U.S. headquarters in Torrance, Calif., has introduced two over-the-counter pain relief patches to the American market, the Salonpas Pain Relief Patch ...

Ultra-Fine Pen Needle for Diabetics Debuts

Becton, Dickinson and Company (BD), based in Franklin Lakes, N.J., has launched the BD Ultrafine Nano, which the company says is the world's smallest pen ...

Legal Issues

Jury Ponders Whether Earlier PSA Would Have Made Difference

Most of Dr. W's cases were referrals from other physicians, often from physicians with whom he was friends.

Malpractice News

Hospital Not Liable for Kidney Transplant Cancer Death

Physicians at a New York hospital have been found not liable for the death of a 37-year old man who died from cancer and receiving ...

Practice Environment Is On The Decline in Massachusetts

The Massachusetts Medical Society (MMS) released its 2010 Physician Practice Environment Index, and the outlook was not good.

Las Vegas Physician Indicted Following Hepatitis Outbreak

The physician owner of a Las Vegas area endoscopy clinic and two nurse anesthetists were indicted on 28 felony counts stemming from a 2008 hepatitis ...

Florida Surgeon Fined for Removing Wrong Organ

The Florida Board of Medicine has fined a Broward County, Fla., surgeon $5,000 for removing a healthy kidney from an 83-year-old patient instead of taking ...

Renal Nutrition Update

Keto Acid Supplements May Help CKD Patients

New evidence supports CKD patient use of keto acid supplements, which provide protein without overloading the kidneys.

General News

Radiotherapy for Prostate Cancer May Raise Hip Fracture Risk

SAN FRANCISCO—Men who undergo three-dimensional external beam radiotherapy (3D-EBRT) for prostate cancer may be at elevated risk for hip fractures, according to researchers.

Overactive Bladder Linked to Inflammation

SAN FRANCISCO—Increasing levels of C-reactive protein (CRP) are associated with increasing odds of overactive bladder (OAB), according to a population-based study of men and women.

Delaying Radical Surgery for Low-Risk Prostate Cancer Could Worsen Outcomes

SAN FRANCISCO—Men with low-risk prostate cancer who delay undergoing radical prostatectomy (RP) for six months or more after diagnosis may have worse outcomes post-operatively than ...

Urinary Health Worse in Prostate Cancer Patients

SAN FRANCISCO—Prostate cancer is associated with significantly increased urinary bother in community-dwelling older men with lower urinary tract symptoms (LUTS), data suggest.

Undetectable PSA 10 Years Post-Op Predicts Low Risk of PSA Relapse

SAN FRANCISCO—Prostate cancer patients who have undetectable PSA levels 10 years after undergoing a radical prostatectomy (RP) have a low likelihood of experiencing biochemical recurrence ...

Time to BCR Affects Survival Likelihood in High-Risk PCa Patients

SAN FRANCISCO—Nearly one in five men who undergo radical prostatectomy (RP) for high-risk prostate cancer experience biochemical recurrence (BCR) within two years of surgery, according ...

Novel Treatment for Premature Ejaculation Shows Promising Results

SAN FRANCISCO—Pivotal clinical trials of a novel treatment for premature ejaculation (PE) have yielded promising results, a researcher announced here at a press conference during ...

Finasteride May Be a Better Choice for Lower Urinary Tract Symptoms

SAN FRANCISCO—Finasteride and dutasteride are similarly effective for treating lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia in properly selected patients, but dutasteride ...

Study: Dogs Can Detect Prostate Cancer by Smelling Urine

SAN FRANCISCO—Dogs can be trained to detect prostate cancer by smelling urine samples and signaling the presence of certain volatile organic compounds (VOCs) produced by ...

High-Grade Prostate Cancer Linked to Diabetes

SAN FRANCISCO—Among obese white men, those with diabetes mellitus (DM) are more likely than non-diabetics to have high-grade prostate cancer discovered on prostate biopsy, according ...

Urine PCA3 Superior to PSA in Predicting Prostate Cancer

SAN FRANCISCO—Urine levels of prostate cancer gene 3 (PCA3) can more specifically predict the presence of prostate cancer than PSA levels, according to new findings.

PSA Rises More Slowly with Age in Diabetics

SAN FRANCISCO—Men with diabetes experience significantly smaller increases in PSA level as they age compared with non-diabetics, according to findings reported here at the American ...

Nocturia May Increase Mortality Risk

SAN FRANCISCO—Nocturia, defined as two or more urinations per night, is associated with an increased risk of death, even after adjusting for comorbidities known to ...

Widely Used Cancer Drug May Cause Renal Damage

Adding bevacizumab to cancer chemotherapy significantly increases the risk of high-grade proteinuria and nephrotic syndrome, according to a new report.

Gout Drug Helps CKD Patients

Allopurinol, a drug used to treat gout, may slow progression of kidney disease in CKD patients, according to new findings scheduled to be published in ...

High Milk Intake Raises Prostate Cancer Risk

High intake of dairy products, especially milk, may increase a man's risk for prostate cancer, a study shows.

Elevated FGF-23 Bad for CKD Patients

It predicts an increased risk of cardiovascular events and death in those not on dialysis.

Statins May Lower Post-op AKI Risk

MONTREAL—Statin use is associated with a decreased risk of acute kidney injury (AKI) after major elective surgery, according to a large retrospective cohort study that ...

Cardiac Patients with Kidney Disease Fare Worse

Kidney disease is present in nearly one third of patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS) and it is a strong independent predictor of ...

Studies Support Earlier Intervention

Doctors may be able to head off ESRD and CVD by treating pre-diabetes and pre-hypertension sooner.

ED Raises Risk of Calcified Coronary Arteries

SAN FRANCISCO—New research implicates erectile dysfunction (ED) as an independent risk factor for high-risk coronary artery calcification.

Anejaculation After RT Common

Most men who undergo radiation therapy (RT) for prostate cancer will develop anejaculation, a new study shows.

Uric Acid May Have a Role in CKD Development

Higher serum uric acid (SUA) levels may independently contribute to the development of CKD, data suggest.

More Bladder Cancer Is Metastatic at Diagnosis

BARCELONA—Researchers have documented a small but significant stage migration in metastatic bladder cancer between 1988 and 2006.

Metallic Ureteral Stents Found Superior

These devices improved patient quality of life significantly better than conventional plastic stents.

Electronic Records May Help Improve BP Control

NEW YORK—New findings suggest that electronic health records (EHR) with special features for managing hypertension may be highly beneficial in improving BP control.

High-Dose Statin Therapy Has Expanded Benefits

Patients with both heart disease and CKD experience decreased risk of cardiovascular events.

Alkaline Phosphatase, Mortality Linked

A study of patients seeking care at an inner-city clinic showed that higher levels of alkaline phosphatase and phosphate are associated with increased mortality.