December 2012 Issue of Renal And Urology News

December 2012 Issue of Renal And Urology News

December 2012

Cover Articles

Abiraterone Benefits mCRPC Patients

Treatment with the drug used in combination with prednisone resulted in significant delays in most measures of pain progression and functional decline.

Kidney Disease Raises Death Risk in Pregnant Women

Kidney disease independently increases pregnant women's risk of death.

Drug May Benefit Patients with ADPKD

Tolvaptan slows kidney growth and renal decline.


Highlights of Kidney Week 2012

Kidney Week 2012, held in San Diego, is now history and as usual I like to reflect on the world's biggest and most prestigious meeting ...

On the Forefront

A Way to Reduce Discard Rates of Kidneys with Capsular Damage

More than 100,000 patients are on the kidney transplant waiting list and the increasing number of patients without living donor options underscore why it is ...

Expert Q&A

The Pregnant Kidney Patient: Interview with Madeleine Pahl, MD

Focusing on nephrology patients who become pregnant may seem to be a niche business, but as specialist Madeleine Pahl, MD, tells Renal & Urology News, ...

News in Brief

Do you think giving patients open electronic access to your visit notes would impede workflow or confuse or worry patients?

A recently published study examined the effect of allowing patients open electronic access to the visit notes of their primary care physicians (PCPs).

New AUA Guidelines: Do More Vasectomies

Vasectomy should be considered for permanent contraception much more frequently.

Clue Found to Dialysis Patients' Heart Risks

The increased risks for cardiovascular mortality in patients with renal failure may be attributable to an impaired endothelial glycocalyx barrier.

Chronic Kidney Disease May Alter Gut Microbes

Microbial DNA revealed marked differences in the abundance of 190 bacterial OTUs between the two groups.

Study: Cranberry Juice Does Not to Prevent UTIs

Cranberry juice is less effective than previously indicated.

Metabolic Factors Boost PCa Mortality, Not Risk

A large, long-term study found no evidence of an association between a high level of metabolic factors and PCa risk.


Current Controversies Surrounding PSA Screening

It is hoped that selective screening, selective biopsy, and selective therapy will 
further decrease the morbidity associated with screening.

Malpractice News

Kansas Supreme Court Upholds Medical Malpractice Award Cap

The court held that the law, which was enacted in 1988, is still an adequate remedy despite the fact that the sum of money is ...

Increased Medical Errors Linked to Chronic Conditions in Kids

Researchers speculate that children with chronic conditions stay in the hospital longer or require more complicated treatments.

Supervisor Support Encourages Nurses to Admit Errors

Researchers noted that their study results demonstrate "the importance of leadership in promoting a work environment in which employees feel it is safe to reveal ...

Renal Nutrition Update

Low Testosterone Increases Risk of Mortality, Anemia, Reduced ESA Response

Testosterone deficiency is common in many patients with CKD, but the treatment of this deficiency and associated side effects have not always received much attention.

Practice Management

Cancellation Fees: How and When to Use Them

Cancellation fees are not meant to fully recoup the missed appointment. Their goal is to change patients' habits.

General News

Post-Nephrectomy Transfusion Rate is Underestimated

The rate of perioperative blood transfusion after nephrectomy appears to be higher in general practice than the rates commonly cited in published urologic reports.

Elderly Do Worse with ECD Kidneys

Graft and patient survival are significantly lower compared with receiving SCD organs.

IMRT Offers Modest Benefit Over 3D-CRT

Men with higher-risk prostate cancer are less likely to need salvage therapy after intensity-modulated radiotherapy.

High-Grade PCa Linked to Greater Percent-Free Testosterone

Twofold increased risk found among men in the highest versus lowest tertile of percent-free testosterone.

Losartan May Protect Renal Allografts from Progressive Fibrosis

The drug was associated with a trend towards less interstitial fibrosis.

Normal Saline Lavage Suitable for Penile Prosthesis Salvage

In a small study, no patient required reoperation for infection.

Novel Program Cuts CMV-Related Admissions in Transplant Patients

High-risk SOT recipients receive chemoprophylaxis initially and are screened frequently for infection.

Tailored UTI Prevention Strategies Proposed

Options include lactobacilli and cranberry preparations.

Pre-Eclampsia Linked to Traffic-Related Pollution

The association is especially pronounced in the third trimester of pregnancy.

HDR Brachytherapy After TURP Okay

It results in less post-radiation major genitourinary complications compared with external beam radiotherapy.

Early BP Control Reduces Cardiovascular Risks in Diabetics

Controlling blood pressure within the first year of hypertension onset reduced the risk of stroke or myocardial infarction by 30%.

Bladder Cancer Linked to Diabetes Drug

A recent meta-analysis reveals that pioglitazone increases the risk of bladder cancer by 22%.

Predictors of Bladder Cancer Recurrence Identified

Advanced pathologic stage and lymph node invasion increase risk of disease return after radical cystectomy.

CKD Complications Linked to BMI, Waist Size

Greater body mass index and waist circumference increases risk of secondary hyperparathyroidism, hyperphosphatemia, and hypertension.

Anogenital Distance Predicts Prostate Cancer Risk

Each 5 mm increase is associated with a 17% decreased risk.

Current Corticosteroid Use Hikes CVE Risk in SLE Patients

Confirming earlier researchers, new study shows that cardiovascular event risk is greater with higher daily doses.

Active Surveillance Recommendations Lagging

Only 21% of urologists and radiation oncologists recommend this management strategy for patients with low-risk prostate cancer.

Invasive MRSA Infections Declining in Dialysis Population

Incidence rates decreased from 6.5 cases per 100 dialysis patients in 2005 to 4.4 cases per 100 dialysis patients in 2010.

Tuberculosis Therapy Effective in CKD Patients

Treatment can cure most cases of TB in this population; the most common complication of therapy is gastritis.

IV Iron Dosing Has Modest Effects at Higher TSAT

Dosing intravenous (IV) iron at higher TSAT levels has only a modest effect on raising transferrin saturation (TSAT), ferritin, and hemoglobin in anemic hemodialysis patients.

Diet May Have No Short-Term Effect on Renal Function

Unhealthy diets are not associated with more rapid declines in kidney function.

Worse Renal Outcomes in CKD Patients Linked to MetS

Metabolic syndrome (MetS) in patients with stage 3 and 4 CKD is associated with an increased risk of development of ESRD.

Predictors of Early Graft Loss Confirmed

Researchers have confirmed previously identified recipient risk factors for early renal graft loss.

Stroke Risk May Be Lower in Peritoneal Dialysis Patients

They may differ from hemodialysis patients with respect to case mix, volume status, disease management, and routine exposure to anticoagulation.

Renal Ultrasound Unwarranted for AKI Evaluation

Obstructive uropathy is rarely found to be a cause of acute kidney injury.

Heart Failure-Renal Dysfunction Link Probed

Researchers have taken another step toward understanding why reduced kidney function gives patients with stable heart failure a significantly increased risk of dying.

RAPN Found Safe for Larger Renal Tumors

RAPN is a possible alternative to open nephrectomy for treating patients with renal tumors larger than 4 cm, researchers say.

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