December 2008 7 12 Issue of Renal And Urology News

December 2008 7 12 Issue of Renal And Urology News

December 2008

Cover Articles

No Benefit from Renal Stents

PHILADELPHIA—Placing renal artery stents in patients with atherosclerotic renovascular disease is not associated with improved outcomes when compared with optimal medical therapy alone.

Personalized RCC Treatment May Be Superior

Clinicians may be able to improve survival rates among patients with renal cell carcinoma (RCC) by tailoring treatments according to risk levels of malignancies, study ...

News in Brief

Metformin Cuts Death Risk

Metformin use by type 2 diabetics is associated with a lower risk of death from cardiovascular disease, according to a recent meta-analysis published in the ...

Statin May Work for Erectile Dysfunction

Atorvastatin may yield improvement in patients whose sole risk factor for erectile dysfunction (ED) is hypercholesterolemia.

Nutrients Fail to Prevent Prostate Cancer

Selenium and vitamin E supplements, taken alone or together, do not prevent prostate cancer, according to an early analysis of data from the Selenium and ...

Percutaneous Nephrolithotomy in Renal Allografts Safe

Percutaneous nephrolithotomy (PNL) in transplanted kidneys is safe and effective, according to a report in The Journal of Urology (2008; published online ahead of print).

New Anemia Drug Safe

Ferumoxytol, a novel, semi-synthetic, superparamagnetic iron oxide nanoparticle administered by injection, is well tolerated and has a safety profile similar to placebo in CKD patients ...

GreenLight HPS Laser Found Safe and Effective for BPH

A short-term follow-up study shows that GreenLight HPS laser photoselective vaporization prostatectomy (PVP) is safe and effective for treating lower urinary tract symptoms secondary to ...

Sudden Cardiac Death Found to Be a Major Killer of Dialysis Patients

Sudden cardiac death (SCD) is the leading cardiovascular cause of death for dialysis patients, researchers reported in Kidney International (2008; published online ahead of print).

Diabetics Benefit from Eating Fish

Eating more fish may lower diabetic patients' risk of macroalbuminuria, new study findings suggest.

Thiamine May Reduce Urinary Albumin Excretion

A British pilot study found that high-dose thiamine therapy reduced urinary albumin excretion (UAE) in patients with type 2 diabetes and microalbuminuria, according to a ...

Feature

A Clinical Dilemma: What is Normal?

The concept of what is "normal" enters into nearly every aspect of clinical decision making. For physicians to declare something abnormal and make a diagnosis, ...

World Literature Review

Symptomatic RCC Predicts Worse Survival, Data Show

Patients with symptomatic renal cell carcinoma (RCC) have worse survival than those who have asymptomatic RCC detected incidentally, according to researchers from the Czech Republic.

Data Support Epoetin Zeta Use in Hemodialysis Patients

Data from a German study suggest that IV-administered epoetin zeta—a new erythropoietin preparation—is safe for maintenance treatment of anemia in patients with end-stage renal disease.

Jaw Problem in Bisphosphonate Users May Be Underestimated

Bisphosphonate-associated osteonecrosis of the jaw (BP-ONJ) may be an underestimated problem in prostate cancer patients treated with zoledronate, German investigators suggest.

FDA News

Pre-Mixed Drug for Hyponatremia Okayed

Vaprisol (conivaptan hydrochloride injection) Premixed in 5% Dextrose, a new formulation of Vaprisol developed by Astellas Pharma US, Inc., has been approved for the treatment ...

Insulin Glulisine for Pediatric Diabetes Cleared

Sanofi-aventis has received approval for Apidra (insulin glulisine [rDNA origin] injection) to improve glycemic control in children aged four years and older with diabetes mellitus.

Alert Issued on Surgical Mesh for Pelvic Organ Prolapse and SUI

The FDA has issued an alert to health-care professionals and the public after receiving reports of complications from the use of surgical mesh to treat ...

New Daily Tablet to Treat OAB Approved

Toviaz (fesoterodine fumarate), manufactured by Schwarz Pharma of Zwickau, Germany, and distributed by Pfizer, has been approved to help patients suffering from overactive bladder (OAB).

Legal Issues

Doctor's Hang Up Blamed for Fatal Pulmonary Embolism

No one likes being put on hold, but, as one physician found out, there is no substitute for direct communication when a patient's life is ...

Renal Nutrition Update

Iron Supplements in CKD: An Update

Iron from dietary sources is inadequate to address functional iron deficiency associated with ESA use.

General News

Catheter-Associated UTIs Raise Death Risk

WASHINGTON, D.C.—Catheter-associated UTIs (CA-UTIs) significantly increase patients' risk of death, researchers have found.

Post-Transplant Bloodstream Infections on the Rise

WASHINGTON, D.C.—The incidence of bloodstream infections (BSIs) in solid-organ transplant (SOT) patients is increasing, and pathogens commonly implicated in these infections show high rates of ...

ADT-Related Anxiety Linked to Elevated PSA

Men with elevated serum PSA levels prior to beginning androgen deprivation therapy (ADT) for prostate cancer are nearly eight times more likely to experience anxiety ...

Age Alone Should Not Deter ADT Use

BOSTON—Age alone should not matter when deciding whether to combine long-term androgen deprivation therapy (ADT) and radiation therapy in men with high-risk prostate cancer, a ...

Program Benefits Poor PCa Patients

Providing free care to economically disadvantaged prostate cancer patients may eliminate racial and ethnic disparities in the use of health resources related to prostate cancer, ...

Stem Cell Homing for Stress Urinary Incontinence

Prevalence data suggest that during their lifetimes, up to half of U.S. women experience some level of female pelvic floor disorders (FPFD). However, despite the ...

Pre-Brachytherapy Hormones May Harm

BOSTON—Men older than 70 years who have localized prostate cancer may be at increased risk of death if they receive neoadjuvant hormone therapy (NHT) before ...

IV Calcitriol May Prevent Parathyroid Gland Growth

IV calcitriol treatment in patients with early-stage secondary hyperparathyroidism prevents parathyroid (PT) gland growth, researchers report.

Cryoablation Procedures Comparable

Laparoscopic (LAP) and CT-guided percutaneous (PERC) cryoablation for renal tumors result in similar short-term outcomes, but the PERC approach may offer advantages with respect to ...

Tallness Hikes Testicular Cancer Risk

Taller men may be at higher risk for testicular cancer, according to German researchers.

New Nomograms May Help Guide ADT Use

BOSTON—Researchers have developed two nomograms that use patients' clinical information to estimate the benefit of adding androgen deprivation therapy (ADT) to radiation therapy.

Kidney Disease Marker Predicts CVD, Diabetes

Two new studies have linked early signs of kidney disease to higher risks for cardiovascular disease and diabetes.

Endocarditis Predictor Falls Short

Bacteremia duration does not accurately predict which hemodialysis (HD) patients will develop endocarditis, according to researchers.

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