August 2011 Issue of Renal And Urology News

August 2011 Issue of Renal And Urology News

August 2011

Cover Articles

BP Meds at Bedtime Reduce CVD Risk

PRAGUE—Taking antihypertensive medications at bedtime significantly reduces cardiovascular disease (CVD) risk compared with ingesting the drugs upon awakening, according to researchers.

RP Beats PADT for Survival

BALTIMORE—Primary androgen deprivation therapy (PADT) does not prolong survival as much as radical prostatectomy (RP) among men with localized prostate cancer (PCa), a new retrospective ...

Diabetes Drug Works Despite Renal Damage

SAN DIEGO—Linagliptin, a dipeptidyl peptidase (DPP)-4 inhibitor, appears to be a good treatment option for patients with type 2 diabetes and severe renal impairment, researchers ...

Commentary

Should We Start Dialysis As Late As Possible?

Traditional nephrology training makes us believe that it is good practice to start maintenance dialysis therapy sooner rather than later. Nevertheless, recent data indicate that ...

News in Brief

FGF-23, Mortality Linked Even in Early-Stage CKD

Elevated levels of fibroblast growth factor 23 (FGF-23) is an independent risk factor for end-stage renal disease (ESRD) in patients with relatively preserved kidney function ...

New Prostate Cancer Drug May Prevent Bone Metastasis

Early data show promising results for cabozantinib, a new therapeutic agent for castration-resistant prostate cancer (CRPC), particularly against tumors that have metastasized to the bone.

FDA Recommend More Conservative Dosing of ESAs

The FDA is calling for more conservative dosing of erythropoiesis-stimulating agents (ESAs) when used to treat anemia in CKD patients due to the increased risks ...

Ambulatory BP Predicts Renal and CV Events

In a study of 436 patients with chronic kidney disease not on dialysis (mean age 65.1 years), ambulatory blood pressure (BP) measurements showed risk of ...

Nocturnal Dialysis May Improve Angiogenesis

Nocturnal hemodialysis significantly improves the ability of early-outgrowth endothelial progenitor-like cells (EPLCs) to promote the growth of new blood vessels and thus restore perfusion in ...

Testosterone Lower in Men with Varicocele

A study comparing 325 men with palpable varicoceles and 510 men with vasectomy reversal without varicoceles revealed that men with varicocele had significantly lower testosterone ...

Feature

Prostatitis and Chronic Pelvic Pain Syndrome: An Update

Etiology and treatment are clearly defined for infectious prostatic syndromes, but not for chronic pelvic pain syndrome.

Legal Issues

Lost Note Exposes a Urologist to Litigation

Dr. Z's office was crowded, but this was nothing new. The 61-year old urologist had built a thriving practice, primarily from referrals from his network ...

Malpractice News

Malpractice Awards in 2010 Lowest on Record

Malpractice awards may be at an all time low in the United States, according to the consumer watchdog group, Public Citizen.

Malpractice Not More Likely with PAs, Most ED Docs Say

Nurse practitioners and physician assistants (PA) are increasingly being used in hospital emergency departments.

Juror in Malpractice Lawsuit Charged with Soliciting a Bribe

In a highly unusual twist to a medical malpractice lawsuit, a juror was arrested in the middle of a trial and accused with soliciting bribes ...

Renal Nutrition Update

Novel Drug Could Prevent Deaths in CKD Patients

Clinical trials show that bardoxolone methyl not only maintains renal function, but improves it.

Your Money

Many Japanese Companies Strong Despite Earthquake and Tsunami

After the earthquake and tsunami struck Japan, markets sank throughout Asia. Investors worried that the devastation would disrupt power producers and hurt a wide range ...

General News

Silodosin Found to Ease CP/CPPS Symptoms

WASHINGTON, D.C.—Silodosin may be an effective treatment for moderate or severe chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), researchers reported at the American Urological Association 2011 ...

PSA Failure Less Likely with EBRT than Cryotherapy for Locally Advanced PCa

MONTREAL—Patients with locally advanced prostate cancer (PCa) have significantly better long-term biochemical disease-free survival (bDFS) if they are treated with external beam radiation therapy (EBRT) ...

Timing of Post-RP Radiotherapy Does Not Affect Complication Rate

MONTREAL—The timing of radiation therapy (RT) after radical prostatectomy (RP) for prostate cancer does not affect the rate of urinary incontinence, bladder neck contracture, and ...

New Findings Confirm Bardoxolone's Efficacy

PRAGUE—Therapy with bardoxolone, an oral antioxidant inflammation modulator, is associated with improved kidney function out to one year in patients with advanced chronic kidney disease ...

Denosumab Lowers Bone Metastasis Risk in CRPC Patients

MONTREAL—Denosumab significantly prolongs bone metastasis-free survival (BMFS) and delays time to bone metastasis in men with castration-resistant prostate cancer (CRPC), according to data presented at ...

Post-Transplantation Anemia Risk Factors Identified

PRAGUE—Renal transplant recipients who have anemia three months after receiving a kidney are more likely to have anemia more than six months post-transplant, according to ...

Study: PD Patients Receive Kidney Transplants Sooner

PRAGUE—End-stage renal disease patients who start on peritoneal dialysis (PD) rather than hemodialysis (HD) spend less time on a renal transplant waiting list before getting ...

QoL in Patients on ADT Unaffected by Provenge

CHICAGO—Prostate cancer (PCa) patients on androgen deprivation therapy (ADT) and receiving sipuleucel-T (Provenge) have no adverse outcomes in terms of quality of life (QoL), according ...

Drug for Advanced RCC Improves PFS

CHICAGO—An investigational drug called axitinib is more effective than sorafenib in prolonging progression-free survival (PFS) in patients previously treated for metastatic renal cell carcinoma (mRCC), ...

Underarm Testosterone Therapy Cleared

WASHINGTON, D.C.—The FDA has approved the first and only testosterone therapy applied to the underarm.

Factors Can Predict Sudden Cardiac Death in Dialysis Patients

VANCOUVER, B.C.—A German team is gathering information to create a tool to accurately predict which dialysis patients are most likely to succumb to sudden cardiac ...

Dual Regimen Benefits Obese Patients

NEW ORLEANS—The combination of sustained-release naltrexone and bupropion leads to sustained clinically meaningful weight loss and improves markers of cardiovascular risk in obese patients, according ...

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