April 2015 Issue of Renal And Urology News

April 2015 Issue of Renal And Urology News

April 2015

Nephrology Cover Articles

Interarm BP Differences Predict Cardiovascular Events in CKD Patients

A difference of 10 mm Hg or more in systolic blood pressure was associated with an 80% increased risk.

Mild CKD Linked to Worse Pregnancy Outcomes

Researchers found 88% higher odds of negative pregnancy outcomes for women with stage 1 CKD and no classic risk factors.

High Fluid Intake Lowers Kidney Stone Risk

Meta-analysis finds a reduction in the risk of incident and recurrent kidney stones.

Urology Cover Articles

Erectile Dysfunction Drugs May Worsen Prostate Cancer Surgery Outcomes

Men who take phosphodiesterase type 5 inhibitors after radical prostatectomy are more likely to experience biochemical recurrence of disease.

Delaying Prostatectomy Appears Safe for AS Patients

No higher risk of adverse pathology among men on active surveillance who delayed surgery until signs of disease progression.

BCG + Sunitinib Promising for High-Risk Bladder Cancer

In a phase 2 trial, 72% of patients with high-grade clinical nonmuscle-invasive bladder cancer had a complete response at 3 months.

Commentary

Whatever Happened to the AIDS Crisis?

Chronic diseases such as end-stage renal disease (ESRD) have now surpassed opportunistic infections as the leading cause of death among HIV-infected patients.

News in Brief

Metformin May Reduce Prostate Cancer Recurrence Risk

Meta-analysis shows that use of medication is associated with an 18% lower risk.

FDA Authorizes Device for Dialysis-Related Amyloidosis

Lixelle Beta 2-microglobulin Apheresis Column authorized for use in DRA

Low-Grade Prostate Cancers Rarely Metastasize

In a study, not a single case of metastatic disease developed among 449 men who had a tumor grade of Gleason 6 or less at ...

Study: Iron-Based Phosphate Binders Good for Renal Anemia

The medication may represent a new treatment option for dialysis patients, researchers concluded.

Uric Acid Predicts eGFR Decline in IgAN Patients

Baseline serum uric acid levels significantly predicted the change in estimated glomerular filtration rate (eGFR).

Practice Management

Women in Practice Could Mean More Flexible Schedules

Practices may need to adjust schedules, time off, and compensation as the number of female urologists and nephrologists grows.

General News

Prostate Capsule, Nerve Sparing Cystectomies Offer Similar Outcomes

In a small randomized trial, functional and oncologic results did not differ significantly between the 2 approaches

Study Hints At a Better Way to Lessen Prostate Biopsy Pain

Patients reported significantly less pain with pelvic plexus block than conventional periprostatic block.

Dialysis Patients with Hyperphosphatemia May Benefit from Magnesium

Higher magnesium levels in hemodialysis patients with high phosphorus levels were associated with decreased cardiovascular mortality.

Delaying Prostate Cancer Surgery Safe in Low-Risk Patients

Researchers find no increased risk of adverse pathologic outcomes among men who put off radical prostatectomy for up to 12 months.

Abiraterone Improves Castration-Resistant PCa Survival

Patients who received the drug as part of their treatment survived longer than those on placebo by a median 4.4 months.

Kidney Disease in Urban Poor Linked to Bad Eating Habits

People least adherent to a DASH-style diet had a 3-fold increased odds of chronic kidney disease compared with those who were most adherent.

Radiation Plus ADT Beneficial in Node-Positive Prostate Cancer

The 5-year risk of overall mortality is decreased by 50% compared with androgen deprivation therapy alone.

High BMI a Plus for Some Metastatic Kidney Cancer Patients

Overweight or obese patients treated with targeted therapy for metastatic clear-cell renal cell carcinoma found to live longer.

Dialysis Patients At Higher Cancer Risk

Over a 5-year period, cancer developed in 9.5% of hemodialysis patients, a rate much higher than would be expected in the general population.

Hurricane Sandy Adversely Affected ESRD Patients

Emergency department visit and hospitalization rates increased in wake of storm.

Time to PCa Metastasis Affects Overall Survival

Median time to death was shortest in men with metastatic disease at diagnosis.

Stroke Risk Increases as GFR Declines

Stroke risk increases linearly with decreasing GFR rate and increasing albuminuria, according to a review and meta-analysis.

Survival Similar with Renal Cryo Techniques

Lapascopic and percutaneous cryoablation for small renal masses are associated with similar survival, researchers say.

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