April 2012 Issue of Renal And Urology News

April 2012 Issue of Renal And Urology News

April 2012

Cover Articles

NSAID Use May Increase Prostate Cancer Risk

PARIS—Contrary to the findings of previous epidemiologic studies, a new study found that use of nonsteroidal anti-inflammatory agents (NSAIDs) is associated with an increased risk ...

Shockwave Therapy Found to Improve Erectile Dysfunction

PARIS—Low-intensity extracorporeal shockwave therapy (LI-ESWT) is an effective treatment option for men with vasculogenic erectile dysfunction (ED), according to findings presented at the 27th Annual ...

Low Renal Function Increases ESRD Risk after Pancreas Transplantation

QUEBEC CITY, QUEBEC—End-stage renal disease (ESRD) eventually develops in more than half of patients with moderate kidney dysfunction at the time of pancreas transplantation, according ...


Is U.S. Nephrology Lagging Behind?

As practicing clinicians in the United States, we generally feel privileged, with access to a highly developed and pioneering medical care system along with an ...

On the Forefront

Sickle Cell Trait and Medullary Renal Carcinoma

Since the discovery of Hemoglobin S (HbS), it has been known that the abnormal polymerization of deoxy-HbS is the main cause for vaso-occlusive crisis involving ...

Sperm Banking To Remote Sites

Infertility is a stressful experience for many couples, a situation made particularly difficult by the need to produce a semen sample in a clinical setting.

Expert Q&A

The Case for Neonatal Circumcision: Interview with Aaron Tobian, MD

Less than a decade ago, Aaron Tobian, MD, PhD, would not have been a proponent of male circumcision.

News in Brief

Are you more likely today to recommend active surveillance for selected patients with low-risk prostate cancer than you were five years ago?

Evidence is accumulating that active surveillance is an appropriate way to manage low-risk prostate cancer in selected men, with curative treatment delayed until it is ...

Device Cleared for Female Urinary Incontinence

The FDA has cleared InTone, a medical device for treating female urinary incontinence.

CP/CPPS May Increase Risk of Colorectal Cancer

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) may put men at increased risk for colorectal cancer, a study found. The association was most prominent among men ...

PCa Risk Higher In Men with Heart Disease

Coronary artery disease (CAD) was associated with a 35% increased risk of a prostate cancer (PCa) diagnosis.

Kidney Donation Does Not Increase CV Risk

Kidney donors are at no greater risk for cardiovascular (CV) events or death than non-donors.

HD Is An Independent Risk Factor for Atherosclerosis

Hemodialysis (HD) is an independent risk factor for atherosclerosis in patents who have chronic renal failure (CRF).

Physician Reminders Fail to Increase ACE/ARB Use

Treatment reminders fail to increase the rate at which primary care physicians (PCPs) prescribe ACE inhibitors or angiotensin receptor blockers (ARBs) for elderly patients with ...


The Impact of Bundling on Clinical Practice

This is the title of a scheduled May 12 session at the National Kidney Foundation's 2012 Spring Clinical Meetings.

Setting Up a Home Hemodialysis Program

As you develop and grow a home HD program, not only will you have wonderful successes, but there will also be challenges and disappointments.

Part II: Clinical Challenges and Renal Considerations in Managing Gout

A case study involving a 65-year-old man with chronic kidney disease and acute attacks of pain, swelling, and erythema in the first metatarsophalangeal joint.

Legal Issues

Physician Sued For Failing to Follow Up

After a negative prostate biopsy, the doctor did not regularly conduct follow-up PSA testing. The patient eventually died from prostate cancer.

Renal Nutrition Update

Oral Adsorbents, Probiotics Inexpensive Way to Eliminate Uremic Toxins in CKD

Patients on a traditional renal diet often find that they are consuming a relatively "unhealthy diet," meaning a diet low in fresh fruits and vegetables, ...

General News

EPO Resistance May Predict Cardiovascular Events

Early identification of erythropoietin (EPO) resistance may help clinicians predict cardiovascular risk in hemodialysis (HD) patients, according to researchers.

Diabetes May Hike Urinary Stone Risk

Diabetes mellitus independently predicts an increased risk of urinary tract calculi (UTC), according to a population-based cohort study conducted in Taiwan.

Persistently Low iPTH Not Good for Hemodialysis Patients

Persistently low levels of intact parathyroid hormone (iPTH) are independently associated with progression of aortic arch calcification (AAC) and death among incident hemodialysis (HD) patients, ...

Prostate Biopsies Rarely Lead to Hospitalization

Hospital admissions related to a prostate needle biopsy (PNB) are on the increase, but they occur in less than 1% of men who undergo PNB ...

Newer Antihypertensive Agents May Be No Better than Diuretics

Calcium channel blockers (CCBs) and ACE inhibitors may be no better than diuretics at preventing cardiovascular deaths in patients with hypertension, according to a follow-up ...

Immunotherapy May Improve mRCC Outcomes

SAN FRANCISCO—An immunotherapy (AGS-003) in combination with sunitinib may help prolong the lives of men with unfavorable risk, metastatic renal cell carcinoma (mRCC), according to ...

Data Support Cystoscopy Prior to Brachytherapy

PARIS—Cystoscopy prior to low dose rate (LDR) brachytherapy for prostate cancer is feasible and useful in identifying patients who require further investigation or intervention before ...

High-Grade Prostate Cancer Linked to Metabolic Syndrome

PARIS—Metabolic syndrome does not increase men's risk of prostate cancer (PCa) overall, but it does increase their risk of aggressive PCa, researchers reported at the ...

Hemodialysis Patients Not More Likely to Die from Renal Cell Carcinoma

PARIS—Hemodialysis (HD) patients are no more likely to die from renal cell carcinoma (RCC) than patients with normal renal function, but they have decreased overall ...

Novel Drug for Overactive Bladder Works Even If Antimuscarinics Do Not

PARIS—Mirabegron, an experimental drug for overactive bladder (OAB), can effectively treat the condition in patients whether or not they failed previous antimuscarinic therapy, according to ...

Severe Pelvic Fracture Impairs Sexual Function

SAN FRANCISCO—Men and women who suffer an acute pelvic fracture that is severe enough to require surgery have a significantly increased risk of a decrease ...

ARF Need Not Prevent Kidney Donation

The use of kidneys from deceased donors with acute renal failure (ARF) can be safe and produce good renal function up to one year after ...

Many Patients Initially Choose PD, but Start on HD

Many patients start dialysis treatment with hemodialysis (HD) even though they initially had opted for peritoneal dialysis (PD), according to researchers.

DCD Kidneys Can Yield Good Outcomes

QUEBEC CITY, QUEBEC—Transplantation of kidneys donated after cardiac death (DCD) can result in good outcomes, a Canadian team has confirmed.

Long-Term Outcomes Similar for ECDs, SCDs

QUEBEC CITY, QUEBEC—Kidneys from standard criteria donors (SCDs) and expanded criteria donors (ECDs) are associated with similar rates of long-term patient survival and death-censored graft ...

Older Age Hikes Admission Risk for Thiazide-Induced Hyponatremia

Researchers have identified risk factors for hospitalizations related to thiazide-associated hyponatremia (HTAH), according to a report in the Journal of Clinical Hypertension (2012;14:158-164).

Finasteride Prevents BPH, Study Finds

Finasteride use decreases the risk of clinical benign prostatic hyperplasia (BPH), according to researchers.

PSA Screening Lowers Prostate Cancer Mortality

PSA-based screening significantly decreases the risk of dying from prostate cancer (PCa), according to updated results of a large European study.

Antibiotic Prophylaxis for Arthroplasty May Promote Acute Kidney Injury

SAN FRANCISCO—New data document a strong association between the use of flucloxacillin with single-dose gentamicin in patients undergoing joint replacement surgery and the development of ...

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