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October 2006 Issue of Renal And Urology News

Editor's Letter

What will become of the scalpel?

Two articles in this issue report on outcomes in patients who underwent holmium laser enucleation for enlarged prostates, called HoLEP for short.

FDA News

New Autoinjector for CKD-Associated Anemia

Amgen is launching its recently approved Aranesp (darbepoetin alfa) prefilled SureClick autoinjector for patients with anemia associated with CKD and chemotherapy-induced anemia.

Prostate Cancer Vaccine Evidence Submitted

Dendreon Corporation of Seattle has presented to the FDA the clinical and non-clinical sections of its rolling submission of a Biologics License Application (BLA) for ...

BPH Treatment Device Returns to Market

Celsion Corporation of Columbia, Md., has announced it will resume shipments of its Prolieve Thermodilatation system for benign prostatic hyperplasia after clearance from the FDA's ...

Further Data on Diabetic Retinopathy Drug Requested

Eli Lilly and Company has received an approvable letter from the FDA requesting additional supporting data for its new drug application for ruboxistaurin mesylate (proposed ...

Patient-Friendly Software for Diabetic Monitoring Cleared

DexCom, Inc., of San Diego has received approval for its DM Consumer Data Manager, a software program that allows diabetic patients to download and view ...

Renal Nutrition Update

Controlling Hyperoxaluria With Diet

NEPHROLITHIASIS results from an interaction between diet and genetic predisposition. Most renal stones contain calcium oxalate, which is why controlling urinary calcium concentration is viewed ...

General News

Age Affects Immunotherapy Response

ADVANCED AGE is associated with a diminished response to intravesical therapy for superficial bladder cancer, a study found.

Antibiotic May Ease Adverse Effects of BCG

PROPHYLAXIS with ofloxacin decreases the incidence of moderate-to-severe adverse effects from bacillus Calmette-Guérin (BCG) intravesical therapy in patients with superficial bladder cancer, French researchers reported. ...

Bilateral Scars May Worsen Outcomes

CHILDREN treated for vesicoureteral reflux (VUR) may be at higher risk of diminished kidney function in middle age if they suffered bilateral renal scarring, investigators ...

Bone Guidelines Okay for PD Patients

WIDELY ACCEPTED guidelines for managing bone metabolism and disease in CKD patients are valid for the peritoneal dialysis (PD) population, Dutch researchers conclude.

Calcification Progression Characterized

CORONARY artery calcification (CAC) progresses after a kidney transplant, but slows between six and 12 months later, researchers reported in the American Journal of Kidney ...

Carotene May Lower BPH Risk

CAROTENE intake may be protective against benign prostatic hyperplasia (BPH), an Italian team of researchers found.

CKD Hikes Stroke Risk in CHD

CKD IS independently associated with an increased risk of ischemic stroke and transient ischemic attack (TIA) in patients with pre-existing atherothrombotic disease, new findings suggest.

Curing PCa with Ultrasound

CLEVELAND—Clinical outcomes using high-intensity focused ultrasound (HIFU) for localized prostate cancer compare favorably to results with radical prostatectomy, while preserving quality of life, Japanese researchers ...

Elevated BMI Cuts Dialysis Death Risk

GLASGOW—A European study confirms that overweight and obese patients have a survival advantage on hemodialysis when compared with normal-weight patients, researchers reported. Furthermore, a weight ...

Expectant Management A Viable Option

ATLANTA--Delayed intervention for treating small renal masses may be appropriate for selected patients, especially those with competing comorbidities, a study found. This conservative approach has ...

HoLEP, TURP Equivalent at Two Years

HOLMIUM LASER enucleation of the prostate (HoLEP) provides two-year outcomes equivalent to that of open prostatectomy in treating men with large prostates, according to two ...

HbA1c Influences GFR Estimates

GLUCOSE CONTROL influences glomerular filtration rate (GFR) and its estimations in patients with type 1 or 2 diabetes, a French study found.

Incontinence Not Always Progressive

URINARY INCONTINENCE in women is not necessarily progressive, but rather it is a dynamic process, Austrian researchers have concluded.

Jaw Problem Tied to Bisphosphonates

BOSTON—IV bisphosphonates may increase the risk of osteonecrosis of the jaw (ONJ), according to new findings.

Cover Articles

Outpatient HoLEP Safe for BPH

CLEVELAND—Outpatient holmium laser enucleation (HoLEP) of the prostate for treating BPH is safe and feasible, improves voiding function, and decreases symptoms of bladder outlet obstruction, ...

LRP Patients Improve For Two Years

CLEVELAND—Men who undergo laparoscopic radical prostatectomy (LRP) can expect that urinary continence and sexual function will continue to improve beyond 12 months following the procedure.

HIV Does Not Worsen Renal Tx Outcomes

TORONTO—One- and three-year outcomes for both patient and graft survival among HIV-infected transplant recipients are comparable to those in the overall transplant population, data show. ...