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May 2007 Issue of Renal And Urology News

May 2007 Issue of Renal And Urology News

World Literature Review

PCa Risk Not Lower in Men with Fluctuating PSA Level

Contrary to what is commonly thought, the risk of having a positive repeat prostate biopsy is no lower for men with a fluctuating PSA level ...
 

Mitomycin C, BCG Comparable For High-Risk Bladder Cancer

A 10-year follow-up study of patients with high-risk bladder cancer shows that mitomycin C (MMC) and bacillus Calmette-Guérin (BCG) have similar effects on disease progression, ...
 

Higher Prostate Cancer Risk Found in BPH Drug Users

Men who take finasteride or alpha blockers for BPH are at higher risk of prostate cancer than non-users, investigators in Finland conclude.
 

Risk Factors for Post-TVT Voiding Problems Identified

Age and maximal peak flow rate before tension-free vaginal tape (TVT) placement are independent risk factors for postoperative voiding dysfunction, a French study found.
 

Hydronephrosis Prolongs Stone Clearance Time

In patients with solitary distal ureteral stones, hydronephrosis is associated with prolonged stone clearance following shock wave lithotripsy (SWL), but the degree of hydronephrosis caused ...
 

FDA News

Immunotherapy for Prostate Cancer Endorsed

FDA’s Office of Cellular, Tissue and Gene Therapies Advisory Committee recommended to the agency that there is substantial evidence of efficacy and safety of Provenge ...
 

Glucose Control Combo Approved for Type 2 Diabetics

Merck announced that Janumet—a single-tablet combination of sitagliptin (Januvia) and metformin—has cleared the FDA.
 

Review for Preventive Kidney Injury Therapy

SR Pharma PLC, of London, announced that the FDA has accepted its Investigational New Drug application (IND) for AKIi-5, a small interfering RNA (siRNA) therapeutic ...
 

New Coated HDL-Raising Tablet Cleared for Treating Lipids

FDA has approved a new, coated version of Niaspan, a once-daily extended-release prescription niacin formulation for the treatment of lipid disorders.
 

Legal Issues

When A Cystoscopy Leads To A Heart Attack

Dr. Y, age 57, is an experienced general urologist who practices at a university hospital in the Northeast. In his clinical setting, the family physician—often ...
 

Malpractice News

Better Hand-offs Needed At Hospital Discharge

Hospital-based physicians are doing a poor job of communicating with their primary-care providers (PCPs) when patients are discharged, according to a recent meta-analysis.
 

Fragmented Surgical System Causes Medication Mistakes

Dangerous medication errors are most likely to occur in surgical settings, according to a pharmaceutical watchdog.
 

General News

Eating Soy May Cut PCa Risk

Men who consume large quantities of isoflavone-rich soy food have a decreased risk of localized prostate cancer.
 

ED Drugs Trump Nitroglycerin

Drugs for erectile dysfunction may be better than nitroglycerin for protecting the heart from damage before and after a severe MI, according to researchers.
 

Changes In Sperm Production And Reproductive Physiology Associated With Aging

Does a man’s ability to father children decrease with age? Interest in this question is increasing because of longer life expectancy, later age of parenting, ...
 

Early Zoledronic Acid Use Beneficial

Treatment with zoledronic acid (Zometa) before onset of skeletal morbidity may lower the risk of skeletal-related events (SRE) and prolong the time to the first ...
 

ED, Stenting Link Shown

Coronary stenting can significantly increase the risk of erectile dysfunction (ED), Chinese investigators report.
 

Epidemiological Aspects Of Parenthood: A National Survey Of Family Growth

In recent years, the media have profiled several high-wattage celebrities in their late 30s and early 40s who are having children. The trend toward delayed ...
 

For Refractory Strictures, A Better Option

SEATTLE—Cutting balloon ureteroplasty may be a safe and effective treatment option for anastomotic strictures resistant to conventional high-pressure balloon dilation, according to findings presented here ...
 

HIFU Effective for Localized Tumors

High-intensity focused ultrasound (HIFU) is a viable treatment option for men with localized prostate tumors who are not candidates for surgery.
 

HoLEP Outcomes Are Durable

BERLIN—Holmium laser enucleation of the prostate (HoLEP) for BPH provides long-term outcomes comparable to those of open prostatectomy, according to a five-year comparison study.
 

IPP May Aid BPH Management

Intravesical prostatic protrusion (IPP) is a useful predictor of outcomes in patients with BPH, studies show.
 

Laparoscopic RP Safe for Elderly

Extraperitoneal laparoscopic radical prostatectomy (eL-RPE) is feasible and efficacious in elderly patients with localized prostate tumors, according to German researchers.
 

Botulinum Toxin Could Be Useful As a BPH Treatment

Botulinum toxin type A (BTX-A) injections may be a promising treatment for BPH patients with urinary retention who are not candidates for surgery.
 

Sorafenib Benefit Unaffected by Prior Cytokine Therapy

Sorafenib treatment doubles progression-free survival in patients with advanced renal cell carcinoma, regardless of whether they have received prior cytokine therapy.
 

Alpha Blocker May Enhance Ureteral Stone Expulsion

Adding the alpha blocker doxazosin to standard treatment may help clear distal ureteral stones, according to researchers in Tashkent, Uzbekistan.
 

PVP, TURP Outcomes Similar

Photoselective vaporization of the prostate (PVP) for BPH provides outcomes similar to those of transurethral resection of the prostate (TURP).
 

Feature

A. Barry Belman: Pediatric Urology Medalist

The most moving part of the ceremony at which A. Barry Belman, MD, received the 2006 Urology Medal at the American Academy of Pediatrics meeting ...
 

Review articles

Bladder Cancer Drug R&D Falls Short

A principal reason for poor outcomes among bladder cancer patients is metastatic disease during follow-up. With currently available drugs, metastatic disease to other solid organs ...
 

Botulinum’s Role in Urology Grows

The use of botulinum toxin (BTX) for various non-urological indications, such as cervical dystonia, blepharospasm, and strabismus has been well accepted for more than a ...
 

High-Risk Bladder Cancer Management

Bladder cancer caught early is often amenable to treatment, but of course late-stage and aggressive characteristics alter the prognosis for the worse. Understanding high-risk features, ...
 

When to Use Intravesical Therapies

BLADDER CANCER is projected to be the fourth most common cancer diagnosed in 2007 and the eighth most common cause of cancer-specific death in men, ...
 

Commentary

Targeted Therapies Include Targeted Surgery

The term “targeted therapy” has entered the oncologic lexicon over the past five years, with primary applications in medical and radiation oncology.
 
 
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