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INFASURF
Lung surfactants/mucolytics
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Drug Name:

INFASURF Rx

Generic Name and Formulations:
Calfactant (as phospholipids 35mg/mL and 0.65mg proteins/mL); susp for intratracheal administration; preservative-free.

Company:
ONY Inc.

Therapeutic Use:

Indications for INFASURF:

Prevention and treatment of respiratory distress syndrome (RDS) in premature infants.

Adult:

Not applicable.

Children:

See literature. Give by intratracheal administration through an endotracheal tube. 3mL/kg birth weight per dose (as 2 aliquots of 1.5mL/kg each) every 12 hours for 3 doses.

Warnings/Precautions:

Interrupt dosing if reflux of product into endotracheal tube, cyanosis, bradycardia, airway obstruction, hypoventilation, or endotracheal tube dislodgement occurs; treat; resume after stabilization. Monitor respiratory status and clinical condition frequently and carefully.

Pharmacological Class:

Lung surfactant.

Adverse Reactions:

Cyanosis, airway obstruction, bradycardia, reflux of surfactant into endotracheal tube, requirement for mechanical ventilation, reintubation, others.

How Supplied:

Single-use vials (6mL)—1

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