Use should be time-restricted or avoided in some patients
Risk is greatest in patients with a lower body mass index and younger age.
Use of either drug is associated with similar incidences of adverse cardiovascular events or death.
In clinical trials, three patients treated with the hyponatremia drug experienced liver injury, which improved after discontinuing treatment.
Tolvaptan slows kidney growth and renal decline.
Hyponatremia is a relatively common electrolyte abnormality in the general U.S. adult population.
Condition is associated with a 44% increased risk of 30-day mortality.
Hyponatremia is associated with shorter cancer-specific survival in patients with metastatic renal cell carcinoma treated with molecular targeted therapy.
Researchers have identified risk factors for hospitalizations related to thiazide-associated hyponatremia (HTAH), according to a report in the Journal of Clinical Hypertension (2012;14:158-164).
Hyponatremia is the most common electrolyte abnormality in both children and adults. New research has begun to challenge some traditionally held views regarding this common condition.
Therapeutic options for SIADH have been significantly enhanced with the introduction of specific vasopressin receptor antagonists
PRAGUE—Transient hyponatremia may precede development of contrast-induced nephropathy (CIN) in patients undergoing coronary angiography, according to investigators.
An 86-year-old black female was admitted to the hospital after she had a seizure while waiting for a swallow evaluation as an outpatient.
Hyponatremia in elderly patients is associated with large-bone fractures, researchers have concluded.
The FDA has approved Samsca tablets (tolvaptan) to treat hyponatremia, one of the most common electrolyte disorders seen in hospitalized patients.
Hyponatremia may be the most common electrolyte disturbance seen in hospitalized patients. It is the most likely to lead to permanent or lethal complications if treated incorrectly.
Astellas Pharma US, Inc., of Deerfield, Ill., has announced the commercial availability of conivaptan hydrochloride injection (Vaprisol) premixed in 5% dextrose.
Hyponatremia may place elderly patients at increased risk for bone fractures, according to researchers.