Latest Hyperuricemia News
In a study of African Americans with hypertension-related CKD, metoprolol, but neither ramipril nor amlodipine, increased serum uric acid levels.
The risk for developing erectile dysfunction is 15% higher among men with than without gout.
All-cause hospitalizations in the US increased 410% from 1993 to 2014 among gout sufferers compared with 4.8% in the general population.
A DASH-style diet is associated with a reduced risk of gout, whereas a Western diet is associated with a higher risk.
Gout is uncontrolled in the majority of individuals with the condition, data show.
The multivariable-adjusted relative risk of hip fracture was 1.38 in women with history of gout.
Blacks had significantly higher median baseline serum urate levels compared to whites.
The allopurinol group had a significant 0.10 mg/dL lower final creatinine level than controls.
The DASH diet lowered serum uric acid, and this effect was greater among participants with hyperuricemia.
Odds of acute kidney injury increases by 29% with each 1 mg/dL increment in uric acid level at ICU admission.
Benefit of adding the uricosuric drug to a xanthine oxidase inhibitor persists for up to 2 years, extension study shows.
The guidelines recommend treatment strategies and state that evidence is insufficient to support therapy to lower uric acid to target levels.
Zurampic, a URAT1 inhibitor, can be combinated with a xanthine oxidase inhibitor to treat hyperuricemia tied to gout.
Serum uric acid levels of 10 mg/dL or higher are associated with an increased risk for nephrolithiasis.
Using the drug together with allopurinol helps more patients achieve target uric acid levels of less than 6 mg/dL.
NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)