Elevated uric acid levels are associated with increased risks for hypertension, gout, and renal impairment.
Many but not all cohort studies examining the relationship between hyperuricemia and CKD outcomes suggest they may be intertwined.
A case study involving a 58-year-old man with acute gout attacks and multiple comorbidities, including hypertension and hypercholesterolemia.
Individuals with first-degree relatives affected by the condition are twice as likely as those in the general population to experienced gout.
Patients with hyperuricemia also had a high prevalence of lower urinary tract symptoms.
Elevated uric acid levels are associated with increased risk of ischemic heart disease and blood pressure, but appear unlikely to cause these problems, a study found.
Patients with gout experienced no clinically significant urate-lowering effects from an 8-week course of a modest dosage of vitamin C.
Systemic review suggests allopurinol can significantly improve estimated glomerular filtration rates.
Adverse events included skin rash, gastrointestinal problems, and allopurinol hypersensitivity syndrome.
Gout prevalence is higher among patients with lower average estimated glomerular filtration rates or higher levels of albuminuria
The two are linked regardless of gender, race, and obesity.
An consumption over a two-year period found to decrease likelihood of a gout attack by 35%.
Data from 5,707 participants of the National Health and Nutrition Examination Survey (NHANES) 2007-2008 show that gout now affects 4% of Americans (8.3 million individuals), and hyperuricemia, 21% (43.3 million).
PARIS—High levels of uric acid are associated with an increased risk of chronic kidney disease (CKD), especially among hypertensive individuals.
Elevated blood pressure is twice as likely in those with a serum uric acid level of 5 mg/dL or higher
Gout patients have an increased prevalence of simple renal cysts, and these cysts are associated with a decreased likelihood of kidney stone disease, according to Brazilian investigators.
PHILADELPHIA—Patients with chronic kidney disease (CKD) have a relatively high prevalence of gout compared with the general population, according to data presented at Kidney Week 2011.
CHICAGO—Uncontrolled serum uric acid in patients with gout is associated with an increased risk of developing kidney disease and diabetes, according to the findings of two studies presented at the American College of Rheumatology annual meeting.