Hyperuricemia Features

Web Exclusives Uric Acid and the Kidney - Is There a Role for Urate Lowering?

Uric Acid and the Kidney - Is There a Role for Urate Lowering?

Many but not all cohort studies examining the relationship between hyperuricemia and CKD outcomes suggest they may be intertwined.

CME Articles

Part III: Clinical Challenges and Renal Considerations in Managing Gout

A case study involving a 58-year-old man with acute gout attacks and multiple ­comorbidities, including hypertension and hypercholesterolemia.

CME Articles

Part II: Clinical Challenges and Renal Considerations in Managing Gout

A case study involving a 65-year-old man with chronic kidney disease and acute attacks of pain, swelling, and erythema in the first metatarsophalangeal joint.

Latest Hyperuricemia News

Urate Lowering May Have Renal Benefits in CKD Patients

Systemic review suggests allopurinol can significantly improve estimated glomerular filtration rates.

Allopurinol-Induced AEs Linked to Colchicine, Statin Use

Adverse events included skin rash, gastrointestinal problems, and allopurinol hypersensitivity syndrome.

Gout Discovered in 30% of Patients with Severe CKD

Gout prevalence is higher among patients with lower average estimated glomerular filtration rates or higher levels of albuminuria

Hypertension Increases Gout Risk

The two are linked regardless of gender, race, and obesity.

Study: Cherries Lower Gout Attack Risk

An consumption over a two-year period found to decrease likelihood of a gout attack by 35%.

Study: Gout Affects 4% of Americans

Data from 5,707 participants of the National Health and Nutrition Examination Survey (NHANES) 2007-2008 show that gout now affects 4% of Americans (8.3 million individuals), and hyperuricemia, 21% (43.3 million).

High Uric Acid Raises CKD Risk, Study Finds

PARIS—High levels of uric acid are associated with an increased risk of chronic kidney disease (CKD), especially among hypertensive individuals.

BP, Uric Acid Linked in Adolescents

Elevated blood pressure is twice as likely in those with a serum uric acid level of 5 mg/dL or higher

Renal Cysts More Common in Gout Patients

Gout patients have an increased prevalence of simple renal cysts, and these cysts are associated with a decreased likelihood of kidney stone disease, according to Brazilian investigators.

Gout Prevalence High in CKD Patients

PHILADELPHIA—Patients with chronic kidney disease (CKD) have a relatively high prevalence of gout compared with the general population, according to data presented at Kidney Week 2011.

Renal Disease, Diabetes Linked to Uric Acid

CHICAGO—Uncontrolled serum uric acid in patients with gout is associated with an increased risk of developing kidney disease and diabetes, according to the findings of two studies presented at the American College of Rheumatology annual meeting.

High Uric Acid Lowers Death Risk in Hemodialysis Patients

High uric acid concentrations are associated with lower all-cause and cardiovascular mortality among hemodialysis (HD) patients, according to an international study.

High Uric Acid Predicts Albuminuria

VANCOUVER, B.C.—Elevated serum uric acid levels strongly predict development of albuminuria in patients with chronic kidney disease (CKD), according to researchers in Romania.

Erectile Dysfunction Linked to High Uric Acid

WASHINGTON, D.C.—Elevated serum uric acid levels may be a marker for an increased risk of erectile dysfunction (ED), Iranian researchers reported at the American Urological Association 2011 annual meeting.

Allopurinol Can Be Used Safely in Renal Transplant Patients on Azathioprine

VANCOUVER, B.C.—Allopurinol can be prescribed safely to treat recurrent gout in renal transplant recipients who are receiving azathioprine, British researchers reported.