Latest Hyperuricemia News
Among CKD patients with an eGFR of 45 mL/min/1.73 m2 or above, each 1 SD increase in baseline uric acid levels is independently associated with a 40% increased risk of kidney failure.
Febuxostat may increase the risk for heart-related death.
Uric acid-lowering therapy might improve kidney outcomes, including kidney failure events, proteinuria, and the rate of change in eGFR, and seem to reduce the risk of cardiovascular events in adults with CKD.
Each 1 standard deviation in baseline uric acid levels was associated with a significant 80% increased odds of rapid kidney function decline.
In a study of African Americans with hypertension-related CKD, metoprolol, but neither ramipril nor amlodipine, increased serum uric acid levels.
The risk for developing erectile dysfunction is 15% higher among men with than without gout.
All-cause hospitalizations in the US increased 410% from 1993 to 2014 among gout sufferers compared with 4.8% in the general population.
A DASH-style diet is associated with a reduced risk of gout, whereas a Western diet is associated with a higher risk.
Gout is uncontrolled in the majority of individuals with the condition, data show.
The multivariable-adjusted relative risk of hip fracture was 1.38 in women with history of gout.
Blacks had significantly higher median baseline serum urate levels compared to whites.
The allopurinol group had a significant 0.10 mg/dL lower final creatinine level than controls.
The DASH diet lowered serum uric acid, and this effect was greater among participants with hyperuricemia.
Odds of acute kidney injury increases by 29% with each 1 mg/dL increment in uric acid level at ICU admission.
Benefit of adding the uricosuric drug to a xanthine oxidase inhibitor persists for up to 2 years, extension study shows.
NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)
Renal and Urology News Articles
- Tamsulosin Improves Clearance of Large Distal Ureteral Stones
- Calciphylaxis in CKD Patients Linked to Hypercoagulable Conditions
- Ceruloplasmin a Possible Marker of CKD in Sickle Cell Anemia
- Post-Parathyroidectomy Calcium Requirement Linked to Preop ALP
- Shift in HIV-Associated Kidney Disease Characterized
- Cytoreductive Nephrectomy Benefits for Metastatic RCC Demonstrated
- Phosphorus Content Higher in Packaged Meats Listing Phosphate Additives
- High Intakes of Teas, Peas, Soybeans May Increase Prostate Cancer Risk
- More Intense Treatment, Worse Quality of Life in Diabetes
- Hemodialysis CRBSI Outcomes Unaffected by Distance to Nephrologists