Many but not all cohort studies examining the relationship between hyperuricemia and CKD outcomes suggest they may be intertwined.
A case study involving a 58-year-old man with acute gout attacks and multiple comorbidities, including hypertension and hypercholesterolemia.
A case study involving a 65-year-old man with chronic kidney disease and acute attacks of pain, swelling, and erythema in the first metatarsophalangeal joint.
Systemic review suggests allopurinol can significantly improve estimated glomerular filtration rates.
Adverse events included skin rash, gastrointestinal problems, and allopurinol hypersensitivity syndrome.
Gout prevalence is higher among patients with lower average estimated glomerular filtration rates or higher levels of albuminuria
The two are linked regardless of gender, race, and obesity.
An consumption over a two-year period found to decrease likelihood of a gout attack by 35%.
Data from 5,707 participants of the National Health and Nutrition Examination Survey (NHANES) 2007-2008 show that gout now affects 4% of Americans (8.3 million individuals), and hyperuricemia, 21% (43.3 million).
PARIS—High levels of uric acid are associated with an increased risk of chronic kidney disease (CKD), especially among hypertensive individuals.
Elevated blood pressure is twice as likely in those with a serum uric acid level of 5 mg/dL or higher
Gout patients have an increased prevalence of simple renal cysts, and these cysts are associated with a decreased likelihood of kidney stone disease, according to Brazilian investigators.
PHILADELPHIA—Patients with chronic kidney disease (CKD) have a relatively high prevalence of gout compared with the general population, according to data presented at Kidney Week 2011.
CHICAGO—Uncontrolled serum uric acid in patients with gout is associated with an increased risk of developing kidney disease and diabetes, according to the findings of two studies presented at the American College of Rheumatology annual meeting.
High uric acid concentrations are associated with lower all-cause and cardiovascular mortality among hemodialysis (HD) patients, according to an international study.
VANCOUVER, B.C.—Elevated serum uric acid levels strongly predict development of albuminuria in patients with chronic kidney disease (CKD), according to researchers in Romania.
WASHINGTON, D.C.—Elevated serum uric acid levels may be a marker for an increased risk of erectile dysfunction (ED), Iranian researchers reported at the American Urological Association 2011 annual meeting.
VANCOUVER, B.C.—Allopurinol can be prescribed safely to treat recurrent gout in renal transplant recipients who are receiving azathioprine, British researchers reported.