Latest Hyperuricemia News
Data show that gout is associated with an increased risk of developing erectile dysfunction.
A study of Medicare patients found that atrial fibrillation was nearly twice as likely to develop in those with vs without gout.
Serum uric acid levels above the median prior to cardiac surgery is independently associated with 5.5-fold increased odds of postoperative acute kidney injury.
Association showed increased risk of all-cause, cardiovascular, and cancer death.
Medication adherence also remained low in patients who reinitiate treatment after a gap in therapy.
Serum urate level is a strong predictor of incident gout, but only about half of patients with hyperuricemia develop clinically evident gout.
US study documents a 27% increase in visits to emergency departments for a primary diagnosis of acute gout from 2006 to 2014.
From 2006 to 2014 in Ireland, the prevalence of hyperuricemia increased from 19.7% to 25.0% among men and from 20.5% to 24.1% among women.
All-cause and cardiovascular mortality risks were 22% and 34% higher among febuxostat-treated patients vs allopurinol recipients.
In a study, CKD patients with high trajectories of serum uric acid had nearly triple the risk for ESRD and 4.5 times the risk for death.
Among CKD patients with an eGFR of 45 mL/min/1.73 m2 or above, each 1 SD increase in baseline uric acid levels is independently associated with a 40% increased risk of kidney failure.
Febuxostat may increase the risk for heart-related death.
Uric acid-lowering therapy might improve kidney outcomes, including kidney failure events, proteinuria, and the rate of change in eGFR, and seem to reduce the risk of cardiovascular events in adults with CKD.
Each 1 standard deviation in baseline uric acid levels was associated with a significant 80% increased odds of rapid kidney function decline.
In a study of African Americans with hypertension-related CKD, metoprolol, but neither ramipril nor amlodipine, increased serum uric acid levels.
NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)
Renal and Urology News Articles
- FDA Recalls Drugs Containing Active Ingredient Valsartan
- Correcting Metabolic Acidosis May Preserve Muscle Mass
- Infection Risk Lower in Dialysis Patients With High, Normal Vitamin D
- Urine Cytology May Not Improve Hematuria Evaluation for Bladder Cancer
- Aggressive Therapy Warranted for Gleason 10 Prostate Cancer