Hypertension News Archive
Mortality risk increased with higher serum digoxin levels; results similar regardless of heart failure
Greater chance of achieving blood pressure target level with combo pill strategy versus usual care
Sodium-BP link persisted after controlling for 13 macronutrients, 12 vitamins, 7 minerals
Using biomarkers to titrate CHF meds may better improve mortality vs. generic titration of all patients
Higher risk of ischemic stroke seen before, after atrial fibrillation diagnosis compared with whites
Gingko biloba plant extract combined with aspirin may help resolve some issues in cognition for acute ischemic stroke patients.
Men who smoked just one cigarette/day had 46% of excess relative risk of smoking 20/day.
The 2017 guideline uses a different classification system for BP than previous guidelines.
Dose-response effect observed in overweight African-Americans with vitamin D deficiency
Silent and clinically manifested MI both correlated with future risk of heart failure in adjusted models.
Effect is larger in chronic heart failure patients with diabetes than CHF patients without diabetes.
Each additional cup consumed per week tied to a decrease in risk compared with no coffee intake.
Updated recommendations lower the blood pressure threshold for a hypertension diagnosis from 140/90 to 130/80 mm Hg.
From 1995 to 2015, the prevalence of hypertension and diabetes among patients starting hemodialysis increased from 67.9% to 87.6% and from 43.1% to 59.6%, respectively.
Study of U.S. veterans found that patients with resistant hypertension had 23%, 31%, and 144% higher risk of myocardial infarction, stroke, and end-stage renal disease, respectively.
Post hoc analysis of SPRINT finds no significant difference in the incidence of fatal and nonfatal cardiovascular events among patients with moderate-to-advanced chronic kidney disease.
Increase in hazard of death with higher mean pulmonary arterial pressure, with no threshold seen.
Patients who show a poor response to a certain dose and medication also show a poor response to higher doses and other RAAS inhibitors or NSAIDs, meta-analysis shows.
Some adolescents may have organ damage related to blood pressure and are not targeted for therapy.
Adverse events up for generic users of losartan, valsartan, candesartan in month of commercialization
Patients were 3 times less likely to take their medications if their providers didn't use a more collaborative style, such as asking open-ended questions, and ensuring they understood instructions, the investigators found.
The researchers found that scores on the cognitive tests were linked with the patient's systolic blood pressure.
In mild AF-related acute ischemic stroke, rivaroxaban and warfarin had comparable safety and efficacy.
Targeting and treating systolic blood pressure to a lower range was associated with a 14% decreased risk of death, meta-analysis shows.
Targeting a systolic blood pressure below 120 mm Hg versus 135 to 139 mm Hg increased the absolute risk of incident CKD by 2.6% over 3 years, but decreased the risk of cardiovascular events or death.
People who increased their weight by as little as 5% were more likely to have thickening and enlargement of the left ventricle.
The researchers found that there was an increase in NOAC use over time, warfarin use did not change, and overall anticoagulant use increased.
After 11 pounds gained, the risk of diabetes went up 31%, hypertension 14%, and cardiovascular disease 8%.
There was no significant difference between the groups in secondary end points or the decreases in NT-proBNP levels achieved.
The researchers found patients on intensive blood pressure treatment fared as well as those on standard care.
In a study of African Americans with hypertension-related CKD, metoprolol, but neither ramipril nor amlodipine, increased serum uric acid levels.
The AAP published updated clinical practice guidelines for the diagnosis and treatment of children with hypertension.
The researchers found that the readmission rate was 18.19% among 5552 patients.
Women at high risk for preeclampsia who took 150 mg of aspirin daily during pregnancy had 62% lower odds of developing the condition.
The researchers found higher estimated cardiovascular risks associated with marijuana use than cigarette smoking.
Fewer VTE events were observed in the betrixaban than enoxaparin arm.
Discontinuation of statin therapy between 3 and 6 months after an index ischemic stroke was associated with a higher risk of recurrent stroke within one year after statin discontinuation.
Heart failure patients on daily aspirin were not at heightened risk of being hospitalized for, or dying from, heart failure.
Patients remain at substantial long-term risk, particularly for recurrent stroke and admission to an institution.
Moderate-severe hypertrophy correlated with a 1.7- and 1.8-fold increased risk of mortality and need for revascularization, respectively.
For every 1000 people in the study, an extra 5.2 cases of atrial fibrillation occurred among those working long hours during the 10 years of follow-up.
The combined data from the clinical trials showed that sudden death rates have fallen by 44% in heart failure patients.
The researchers found that the estimated one-year cumulative incidence of ischemic stroke was 1.4% and major bleeding was 1.2%.
The researchers observed an overall reduction in all-cause mortality, from 28.26% with conventional care to 21.37% with ICD therapy.
Between 2002 and 2013, heart failure hospitalizations declined by 30.8% nationwide, and continue to drop.
The researchers found that cardiology care correlated with significant reductions in stroke and death.
The researchers found that the associated risk of MI was increased for ASA and dual therapy relative to the VKA-treated group.
The researchers found that new-onset AF correlated with increased risk of heart failure in multivariable models.
Earlier treatment remained significantly correlated with lower in-hospital mortality in multivariate analysis.
CKD patients treated to a target systolic blood pressure of less than 120 mm Hg were 28% less likely to die early.
Combining quarter doses of two drugs was as effective as a single standard dose of one blood pressure-lowering medication.
The researchers observed linear associations between mean achieved SBP and risk of cardiovascular disease and mortality.
Compared with individuals reporting chocolate intake less than once per month, the rate of AF was lower for people consuming chocolate regularly.
Dietary sodium intake guidelines may be misguided.
A total of 16 men had received an LVAD and then had it removed because they had significant recovery of heart function.
The risk of major bleeding is similar for older patients with atrial fibrillation taking either antiplatelet or anticoagulant drugs.
As 25(OH)D levels increased, systolic blood pressure decreased significantly, even after accounting for calcium intake.
A majority of sodium consumed was from food obtained at stores; however, sodium density was highest in food obtained at restaurants.
Higher mid-life BMI was significantly associated with greater risk of HF hospitalization after adjusting for established HF risk factors.
The majority of the ischemic cardiomyopathy patients showed improvement in pulmonary artery pressure, pulmonary capillary wedge pressure, pulmonary vein resistance, and left ventricular wall stress.
MRI measurements reflecting RV structure and stiffness of the proximal pulmonary vasculature are independent predictors of outcome in PAH.
Overall, patients on omega-3 supplements had an 8% lower risk of total mortality or hospitalization for cardiovascular disease over 4 years.
Study documents higher risks even when creatinine increases are less than 30%, the guideline-recommended threshold for stopping treatment.
Blood pressure targets below 130/80 and below 140/90 mm Hg are associated with similar renal outcomes among non-diabetics, meta-analysis shows.
People with high blood pressure consumed an average of 2,900 mg of sodium per day in 1999 and 3350 mg per day in 2012, for an overall average daily sodium intake of 3100 mg.
Changes over time in prescription adherence are common and affect treatment estimates considerably.
Numerous population studies demonstrate a relationship between higher dietary K+ and lower blood pressure regardless of sodium intake.
Among the etiologies of readmission, cardiac causes including heart failure and coronary artery disease were most common.
With dietitian counseling, limiting sodium to 2000 mg per daily is feasible for chronic kidney disease patients.
Adjusted rates of hospitalization for AF increased by almost 1% per year between 1999 and 2013.
In the United States, more than 92.1 million people have cardiovascular disease.
An estimated 12.3% of Americans over the age of 21 have masked hypertension.
New guidelines suggest aiming for a systolic pressure less than 150 mm Hg in hypertensive individuals aged 60 or older.
With respect to mortality and hospitalizations, there were no significant interactions for β-blockers and pattern or burden of AF.
To receive top ratings, a diet has to be relatively easy to follow, nutritious, safe, effective for weight loss, and protective against diabetes and heart disease.
United States, China, India, Indonesia, and Russia accounted for more than 50% of elevated or high blood pressure cases.
Clinically important heterogeneity in intensive BP treatment remains undetectable in conventional trial designs but can be detected in sequential randomization trial designs.
Spironolactone use was associated with 12% decreased odds of prostate cancer in male patients and 19% decreased odds of bladder cancer in female patients.
Using beta-blockers was also associated with a higher risk of patient's reduced ability to perform daily functions independently.
The DASH diet lowered serum uric acid, and this effect was greater among participants with hyperuricemia.
Nearly a third of hypertensive participants were not adherent to antihypertensive drug therapy.
Conditions such as chronic illness, mental illness, or substance abuse commonly overlap with each other and with poverty, which contributes to poor health.
The findings suggest that living in a polluted environment could promote development of hypertension, cardiovascular disease, and stroke.
Lack of association observed in study of hypertensive patients with normal renal function.
According to the authors, the influence of midlife hypetertension may lead to late-life impaired cognitive function.
Blacks have increased incidence of hypertension, diabetes mellitus, dyslipidemia, but not a-fib.
Findings support modest reductions in sodium intake among persons consuming high-sodium diets
Increased SBP variability tied to mortality, coronary heart disease, stroke, end-stage renal disease
Data from 21 observational studies showed an 8% increased risk of prostate cancer.
Losartan treatment is linked to aldosterone reductions in patients with hypertension but not obstructive sleep apnea.
Findings indicate high-risk adults would benefit from intensive program to lower SBP to 120 or less.
Add-on mineralocorticoid receptor antagonist therapy increased serum potassium by 0.4 mEq.
Low DBP linked to myocardial damage, CHD events especially among those with SBP 120 mm Hg.
Significantly higher nighttime systolic blood pressure, especially in patients with diabetes and low eGFR.
Black CKD patients with strict blood pressure control had a 19% lower risk of premature death.
Sleep apnea with resistant HTN linked to increased risk of ischemic heart event, congestive heart failure.
Low aerobic capacity has greater effect than even high cholesterol, high blood pressure.
Commonly used meds linked to increased risk of hospitalization for dehydration, heat-related illness.
Notable improvement seen with carvedilol and nebivolol, but not betaxolol.
Future studies are needed to assess potential benefits of hypertension screening for daytime nappers.
Renal and Urology News Articles
- Aggressive Therapy Warranted for Gleason 10 Prostate Cancer
- PET/CT May Improve Imaging of Recurrent Prostate Cancer
- Adding MRI Does Not Boost Prostate Cancer Upgrading Rate
- Both High and Low Uric Acid Levels Tied to Higher Mortality
- Trulicity Labeling Updated to Include Data on T2D Patients With CKD
Sign Up for Free e-newsletters
NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)