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Study Identifies RCC Risk Factors

May 19, 2012

A history of kidney disease, hypertension, high body mass index (BMI), and smoking are independently associated with an increased risk of renal cell carcinoma (RCC), researchers reported at the American Urological Association 2012 annual meeting.
 

Page Kidney Resulting in New Onset Hypertension

, May 01, 2012

A 55-year-old Caucasian woman initially presented to one of Cleveland Clinic's regional outpatient urology clinics with gross hematuria and an obstructing right ureteral stone.
 

Remoteness May Affect Hypertension Risk

April 23, 2012

Hypertension risk among individuals living in rural areas may depend on the distance of their residence from population centers, according to a study conducted in Japan.
 

BP, Uric Acid Linked in Adolescents

April 09, 2012

Elevated blood pressure is twice as likely in those with a serum uric acid level of 5 mg/dL or higher
 

Differences in Interarm BP Linked to Increased Mortality

March 21, 2012

For patients with hypertension, systolic difference of 10 to 15 mm Hg significantly increases death risk
 

Unusual Manifestation of an Aldosterone-Producing Adenoma

, , February 29, 2012

Primary aldosteronism was first described by Jerome Conn in 1955 in a patient with an aldosterone-producing adrenal adenoma. It's now a widely recognized cause of secondary hypertension.
 

Resistant Hypertension Secondary to Primary Aldosteronism

, , , February 29, 2012

A 43-year-old man was evaluated for uncontrolled hypertension (HTN) despite multiple drug therapy, which included amlodipine 10 mg daily, clonidine 0.3 mg BID, and metoprolol XL 200 mg BID.
 

Health Care Workers Should Promote Dietary Salt Reduction

February 29, 2012

Historically, salt has been a commodity, a preservative, and a flavor enhancer. The salt shaker has a special place in most kitchens or dining room tables.
 

Pulmonary Hypertension Common in Hemodialysis Patients

February 10, 2012

Pulmonary hypertension is common in hemodialysis (HD) patients and it is associated with an increased death risk, a study found.
 

Change in Fitness or Fatness Impacts Cardio Risk Factors

February 06, 2012

Positive change in fitness or fatness impacts cholesterol, hypertension, metabolic syndrome
 

Newer Antihypertensive Agents May Be No Better than Diuretics

January 20, 2012

Calcium channel blockers (CCBs) and ACE inhibitors may be no better than diuretics at preventing cardiovascular deaths in patients with hypertension, according to a follow-up study of patients in a seminal antihypertensive trial. In addition, CCBs and ACE inhibitors may increase cardiovascular risks.
 

Vitamin D Has No Blood Pressure Effect in Postmenopausal Women

December 06, 2011

Serum levels of 25-hydroxyvitamin D (25(OH)D) are not related to changes in blood pressure (BP) in postmenopausal women, according to researchers.
 

Supplemental Vitamin D Helps Black Hypertensives

November 22, 2011

ORLANDO—Vitamin D supplementation may reduce blood pressure (BP) in African-American patients with hypertension in a dose-dependent manner, regardless of the intensity of antihypertensive treatment, researchers announced at the American Heart Association Scientific Sessions 2011.
 

Racial Disparity in Albuminuria Linked to Vitamin D

October 10, 2011

Vitamin D levels may account for racial differences in albuminuria and vascular-related conditions, according to researchers.
 

Fruits, Vegetables Boost BP Control

September 13, 2011

PARIS—A diet rich in fruits and vegetables can lower blood pressure in patients with coronary heart disease, according to data presented at the European Society of Cardiology annual meeting.
 

Issues in Hypertension: An Interview with George Bakris, MD

September 01, 2011

George Bakris, MD, Professor of Medicine and Director of the Hypertensive Diseases Center at the University of Chicago Medical Center, is an internationally recognized hypertension expert who specializes in complicated or refractory cases. He spoke with Renal & Urology News about various aspects of treating hypertension in patients with chronic kidney disease.
 

RAS Blockade Improves Transplant Patient Survival

July 19, 2011

Medications that block the renin-angiotensin system (RAS) may improve survival among renal transplant recipients, according to researchers.
 

BP Meds at Bedtime Reduce CVD Risk

June 28, 2011

PRAGUE—Taking antihypertensive medications at bedtime significantly reduces cardiovascular disease (CVD) risk compared with ingesting the drugs upon awakening, according to researchers.
 

Hypertension Risk in Men Increases Along with Alcohol Intake

May 31, 2011

NEW YORK—The more alcohol a man drinks per day, the greater his risk for developing hypertension, according to a recent study.
 

Triple BP Drug Combo Safe, Effective Long Term in Elderly Patients

May 25, 2011

NEW YORK—Long-term data show that a three-drug combination is safe and effective for treating hypertension in elderly patients, according to a report at the American Society of Hypertension annual meeting.
 

Dual Regimen Lowers BP in Older Patients with Diabetes or Metabolic Syndrome

May 24, 2011

NEW YORK—A combination of aliskiren and hydrochlorothiazide (HCTZ) is an effective first-line treatment option for older patients with stage 2 hypertension, even those with diabetes or metabolic syndrome, investigators concluded.
 

BNP Level Prior to Renal Artery Stenting Does Not Predict BP Outcomes

May 14, 2011

Brain natriuretic peptide (BNP), a substance secreted by the heart that is associated with congestive heart failure and renal failure, does not predict reduction in systolic blood pressure (BP) in patients treated with renal artery stenting, according to results from the HERCULES trial.
 

Many Very Old Individuals Have Masked Hypertension

May 05, 2011

Masked hypertension (MHT)—which is blood pressure (BP) that appears normal when measured in doctors' offices but which is found to be elevated when measured at home—may be common in people aged 75 years and older, according to a French study.
 

Pulmonary Hypertension After a Lung Transplant Predicts RRT Need

April 29, 2011

LAS VEGAS—Pulmonary hypertension is a strong predictor of the need for renal replacement therapy (RRT) after lung transplantation, according to new findings presented at the National Kidney Foundation's Spring Clinical Meetings.
 

Morning Blood Pressure Surge May Not Increase Death Risk

April 22, 2011

Morning blood pressure (BP) surge is widely believed to increase cardiovascular disease risk, but a new study suggests that an increase in morning BP over nocturnal levels may represent a healthier form of circadian variation and may not have an adverse predictive nature but rather a favorable one when it comes to all-cause mortality.
 

Drug-Eluting Stents for Renal Artery Stenosis Offers Better Outcomes

April 09, 2011

CHICAGO—Drug-eluting stents (DES) may achieve better outcomes than bare metal stents in the treatment of renal artery stenosis (RAS), according to researchers.
 

Renal Denervation Found to Treat Resistant Hypertension

March 29, 2011

CHICAGO—Renal denervation (RDN), a new procedure in which a catheter-based probe inserted is into the renal artery to deactivate nerves near the kidneys with high-frequency energy, may be effective for treating resistant hypertension, according to French researchers.
 

CKD Develops in Many Living Kidney Donors

March 19, 2011

VIENNA—One year after undergoing living donor nephrectomy (LDN), more than half of donors will have chronic kidney disease (CKD), according to a British study. Their decline in renal function, however, appears to remain stable for at least five years and patients rarely suffer adverse cardiovascular events and cardiac mortality.
 

Reducing Salt Benefits Teens Later On

February 11, 2011

Cutting intake by only 3 grams a day would greatly reduce the number of future cardiovascular events.
 

Geography, Race, Gender Affect Hypertension Risk

January 14, 2011

The risk of developing hypertension may depend on where in the United States a person lives as well as his or her gender and race, according to a study.
 

High Uric Acid May Raise Risk of Hypertension

January 05, 2011

High uric acid levels may be a risk factor for hypertension, according to a new meta-analysis.
 

Football May Increase Hypertension Risk

December 10, 2010

CHICAGO—While the impact of football on health outcomes has focused largely on head injuries, new findings suggest that football training may also lead to pre-hypertension.
 

Renal Denervation Helps Resistant Hypertensives

December 08, 2010

CHICAGO—Catheter-based renal denervation significantly decreases blood pressure (BP) in patients with treatment-resistant essential hypertension, according to results released at the American Heart Association Scientific Sessions 2010 and simultaneously published online in The Lancet.
 

Study: Watermelon Helps Fight Hypertension

November 02, 2010

A new study out of Florida is suggesting that watermelon can be an effective natural weapon against pre-hypertension. John Schieszer has the latest on these new study findings in today's Medical Minute.
 

Brand Name for Epoprostenol for Injection Okayed

October 29, 2010

The FDA has approved the brand name for commercially available Veletri (epoprostenol for injection) for pulmonary arterial hypertension (PAH).
 

Lower BP in CKD Helps Only When Proteinuria is Present

October 22, 2010

Intensive BP control is no better than standard BP control at protecting against progression of kidney disease among African Americans with CKD, except perhaps if proteinuria also is present, according to findings published in the New England Journal of Medicine (2010;363:918-929).
 

Aging Alone Does Not Influence CKD

September 24, 2010

A study of 2,649 men and women aged 18 years and older has uncovered no evidence that aging alone influences CKD, instead identifying hypertension as the only comorbid condition to contribute to kidney damage in both men and women, according to a report in the Journal of Nephrology (2010;23:444-452).
 

Living Kidney Donor Outcomes Vary by Race

August 19, 2010

Black and Hispanic living kidney donors are at increased relative risk for hypertension, diabetes requiring drug therapy, and CKD compared with their white counterparts, according to researchers.
 

Report: Data Do Not Justify Advised BP Goals in CKD

August 19, 2010

The target BP level of less than 130/80 mm Hg for CKD patients—which is recommended by a Kidney Disease Outcomes Quality Initiative guideline—is not definitively supported by scientific data and could potentially lead to adverse effects.
 

Electronic Records May Help Improve BP Control

July 28, 2010

NEW YORK—New findings suggest that electronic health records (EHR) with special features for managing hypertension may be highly beneficial in improving BP control.
 

Studies Support Earlier Intervention

July 27, 2010

Doctors may be able to head off ESRD and CVD by treating pre-diabetes and pre-hypertension sooner.
 

BP Lowering Better with a Triple Regimen

July 12, 2010

NEW YORK—An investigational triple regimen of olmesartan medoxomil (OM), amlodipine besylate (AML), and hydrochlorothiazide (HCTZ) may result in significantly greater mean reductions in BP compared with a combination of any two of these drugs in patients with moderate to severe hypertension, new data show.
 

Increased Hypertension Risk Found in Live Kidney Donors

June 26, 2010

MUNICH, GERMANY—Live kidney donors may experience an increase in blood pressure following nephrectomy, new data suggest.
 

BP Guidelines May be Inappropriate for HD Patients

May 21, 2010

SEATTLE—Guidelines recommend that hemodialysis (HD) patients have predialysis BP levels below 140/90 mm Hg, but study findings suggest that such levels may increase their risk of death, according to David Goodkin, MD, an investigator with Arbor Research Collaborative for Health.
 

New Formulation of PAH Medication Is Now Available

May 21, 2010

Epoprostenol for Injection, an improved formulation of epoprostenol that is stable at room temperature, is now commercially available, according to the drug's maker, Actelion Pharmaceuticals US, Inc., of South San Francisco, Calif.
 

Olmesartan Cleared for Treating Hypertension in Children

March 30, 2010

The FDA approved the use of Benicar (olmesartan medoxomil) for the treatment of hypertension in individuals aged 6 to 16 years. The drug original was cleared in 2002 for the treatment of adult hypertension.
 

Resistant Hypertension Tied to Less Sleep

March 30, 2010

Short sleep time and poor sleep efficiency may have an etiologic role.
 

Reduced Salt Intake Could Yield Big Benefits

March 30, 2010

Modest reductions in dietary salt intake can help reduce the risk of cardiovascular events and significantly lower medical costs, a study found.
 

BP Drug Combination May Offer Better Renoprotection

February 17, 2010

Use of benazepril with amlodipine rather than hydrochlorothiazide is more effective at slowing CKD progression.
 

ACE Inhibitors, Angiotensin Receptor Blockers Have Heart Benefits in Hemodialysis Patients

February 16, 2010

Study finds that the drugs reduce left ventricular mass.
 

Hypertension, Fructose Intake Linked

January 22, 2010

Those who consume 74 grams or more of fructose daily are at higher risk than those who consume less.
 

Cocoa Can Decrease Blood Pressure, Study Shows

January 05, 2010

Cocoa products such as dark chocolate and cocoa-containing beverages can lower blood pressure, a recent meta-analysis confirms.
 

Spironolactone Improves Renoprotection in Patients with Diabetes and Hypertension

January 04, 2010

Adding spironolactone to a regimen that includes maximal ACE inhibition improves renoprotection in patients with diabetic nephropathy, data suggest.
 

Insurance Gaps Affect Use Blood Pressure Medications

December 14, 2009

Hypertensive patients who experience gaps in their health insurance coverage are less likely to continue with their anti-hypertensive medications, according to researchers.
 

FDA Approves Aliskiren/Valsartan Combination Pill

October 16, 2009

FDA has approved Valturna (aliskiren and valsartan) tablets, which the drug's maker, Novartis, of East Hanover, N.J., said is the first and only product to target two key points in the renin angiotensin aldosterone system (RAAS).
 

Hypertension: A Public Health Challenge

, October 16, 2009

Hypertension rates are expected to rise due to a growing prevalence of obesity and other risk factors.
 

Obesity Raises Prehypertensives' Risk

October 12, 2009

In a study, prehypertensive patients with the highest BMI had a sixfold increased risk of treated end-stage renal disease or CKD-related death.
 

Aliskiren-HCTZ Combo Okayed as First-Line Therapy

September 17, 2009

Tekturna HCT, a single-pill combination of aliskiren—the first and only approved direct renin inhibitor—and hydrochlorothiazide (HCTZ) has been approved as initial therapy for patients who are likely to need multiple drugs to achieve their BP.
 

Treatment for Pulmonary Arterial Hypertension Cleared

September 17, 2009

The FDA has cleared Tyvaso (treprostinil) Inhalation Solution for the treatment of pulmonary arterial hypertension (PAH).
 

Redefining Hypertension for Tomorrow: Target Levels

September 01, 2009

There is sufficient evidence to demonstrate that lowering BP to less than 140/90 mm Hg offers cardiovascular and renal protection.
 

Treating RAS: To Stent or Not to Stent?

August 19, 2009

An interventional cardiologist and two nephrologists debate the issue at a major medical conference.
 

Test Renin To Guide BP Med Choice

August 18, 2009

Plasma renin testing provides an effective, practical, and possibly superior way to improve BP control in patients with treated but uncontrolled hypertension, a study found.
 

Combo AIds Hypertensives with LUTS

August 10, 2009

Amlodipine plus terazosin achieved better BP control that either drug alone, according to researchers.
 

New Method Predicts Stent Responders

July 20, 2009

Renal frame count can indicate likelihood of successful outcomes in patients with renal hypertension
 

BP Drug Lowers Cystatin C

July 13, 2009

Olmesartan medoxomil decreases serum cystatin C levels in hypertensive patients, suggesting that this agent can counteract renal damage, according to a study published in Blood Pressure (2009; published online ahead of print).
 

High BP in Most Kids Can Be Controlled

July 13, 2009

BALTIMORE—New data demonstrate that BP can be successfully managed in most adolescents who have essential hypertension.
 

Pulmonary Hypertension in HD Patients Increases Death Risk

June 18, 2009

Pulmonary hypertension (PHT) independently predicts greater mortality in hemodialysis (HD) patients, Israeli researchers report.
 

A Downside to Angiotensin Blockade?

June 18, 2009

Researcher Macaulay Onuigbo, MD, MSc, proposes that ACE inhibitors and angiotensin receptor blockers can cause renal failure.
 

Greater Fitness Improves Survival in Prehypertensive Men

June 15, 2009

Improvements in exercise capacity are associated with decreased mortality among prehypertensive men, data show.
 

Pediatric Hypertension Can Be Readily Controlled

June 04, 2009

BALTIMORE—New data demonstrate that BP can be successfully managed in most adolescents who have essential hypertension.
 

Diet May Reduce Hypertension Risk

May 12, 2009

A diet rich in fruits and vegetables lowers the risk of hypertension, but only among individuals with a low intake of olive oil, according to a prospective study of a population following a Mediterranean-type diet.
 

Combo Superior for Microalbuminuria

May 11, 2009

Telmisartan plus amlodipine is superior to losartan plus amlodipine in reducing microalbuminuria in hypertensive patients with type 2 diabetes, Italian researchers reported.
 

Hypertension More Common in Black than White Diabetics

May 11, 2009

African-American diabetics have a significantly higher prevalence of hypertension than Caucasian diabetics, a study suggests.
 

Low Vitamin D May Raise Hypertension Risk

May 08, 2009

Vitamin D deficiency may increase the risk of hypertension, according to investigators.
 

Excessive BP Lowering May Be Harmful

May 08, 2009

Low BP may increase the risk of cardiovascular events in patients with coronary artery disease (CAD), despite substantial lowering of LDL cholesterol, according to new findings.
 

Novel Ways to Control BP

May 01, 2009

ORLANDO—At the American College of Cardiology annual meeting here, researchers reported promising results for two novel approaches to treating medically resistant hypertension.
 

BP Lowering May Benefit All Diabetics

April 22, 2009

BP-lowering may provide renoprotection in patients with type 2 diabetes, regardless of baseline BP level.
 

Hypertension Linked to RCC

March 01, 2009

Surgery for kidney cancer may help resolve concomitant arterial hypertension, according to a study.
 

Megadosage Candesartan Beneficial

February 18, 2009

Renal disease patients who have persistent proteinuria despite treatment with the highest approved dosage of the angiotensin receptor blocker candesartan may benefit from higher dosages, a Canadian study finds.
 

Higher Heart Rate Increases Obesity, Diabetes Risks

February 13, 2009

Higher heart rates may predispose individuals to the development of obesity and diabetes mellitus, according to a 20-year prospective Japanese study of 614 participants older than 20 years.
 

Hypertension, Acid Excretion Are Linked in Stone Formers

February 04, 2009

Kidney stone formers with essential hypertension have increased acid excretion, Italian researchers reported.
 

BP Response to Dietary Sodium Changes Greater in Women

February 04, 2009

Reducing dietary sodium may be more effective at lowering BP in women than in men, researchers reported in the Journal of Hypertension (2009;27:48-54).
 

Study: CKD Outcomes Differ in African Americans

January 30, 2009

PHILADELPHIA—African Americans with hypertension-related CKD may be more likely to progress to end-stage renal disease (ESRD) than die from cardiovascular disease (CVD), the opposite of what has been reported for other CKD populations in many studies, researchers conclude.
 

Important Lessons from ONTARGET

January 09, 2009

In the past year, an important landmark study demonstrated therapeutic equivalence of the ACE inhibitor ramipril and the angiotensin receptor blocker (ARB) telmisartan in reducing the risk of all forms of atherosclerotic events.
 

Aliskiren Offers Better BP Control

November 25, 2008

ROME—Aliskiren, an oral direct renin inhibitor, lowers BP more effectively than hydrochlorothiazide as monotherapy or with add-on amlodipine in obese patients with hypertension, according to results reported here at the 44th annual meeting of the European Association for the Study of Diabetes.
 

No Benefit from Renal Stents

November 17, 2008

PHILADELPHIA—Placing renal artery stents in patients with atherosclerotic renovascular disease is not associated with improved outcomes when compared with optimal medical therapy alone.
 

Stents May Shorten Dialysis Duration

November 12, 2008

Renal artery stent placement in hemodialysis (HD) patients who have renal artery stenosis (RAS) can restore sufficient kidney function to allow discontinuation of HD, a study suggests.
 

BP Drug May Reduce Cardiovascular Risks

November 11, 2008

Amlodipine treatment may reduce cardiovascular risks in hypertensive hemodialysis patients, according to German researchers.
 

Dual Regimen Cuts Cardiac Mortality Risk

November 01, 2008

Supplementing diuretic therapy with a drug that conserves potassium reduces the overall risk of cardiac mortality as well as the risk of sudden cardiac death (SCD), according to a meta-analysis conducted by researchers at Vanderbilt University in Nashville.
 

ABPM May Help Control Post-Transplant Hypertension

November 01, 2008

Repeated ambulatory BP monitoring (ABPM) may help to improve BP control in hypertensive pediatric renal transplant recipients, data suggest.
 

Target Microalbuminuria Aggressively

September 02, 2008

NEW ORLEANS—Microalbuminuria is a biomarker for vascular disease and warrants aggressive treatment, which may prevent progression to overt nephropathy and reduce the risk of cardiovascular events, said Debjani Mukherjee, MD, at the 23rd scientific meeting of the American Society of Hypertension.
 

Normal ACR Can Raise Risk of High BP

September 02, 2008

Hypertension is more likely to develop in women with high but normal albumin/creatinine ratios (ACRs) than in women with lower ACRs, according to a new analysis of data from the Nurses' Health Studies (NHS).
 

ARBs May Lower CVD Event Risk in Hemodialysis Patients

September 01, 2008

Treatment with angiotensin receptor blockers (ARBs) may reduce the risk of fatal and non-fatal CVD events in hemodialysis patients, according to researchers at the Saitama Medical University in Saitama, Japan.
 

Salt May Lower ARB Efficacy in Diabetics

September 01, 2008

SAN FRANCISCO—Dietary salt supplementation may reduce the antihypertensive effects of the angiotensin receptor blocker (ARB) telmisartan in patients with type 2 diabetes and hypertension, investigators reported at the 68th Scientific Sessions of the American Diabetes Association. The effect is independent of habitual sodium dietary status.
 

Single-Pill First-Line Combo Drugs for High BP Cleared

September 01, 2008

The FDA has approved two single-pill combination drugs, Diovan HCT (valsartan and hydrochlorothiazide) and Exforge (amlodipine and valsartan), as first-line treatments in patients likely to need multiple drugs to manage hypertension.
 

First New IV Antihypertensive Treatment in a Decade Approved

September 01, 2008

The Medicines Company of Parsippany, N.J., has received approval for its IV-administered Cleviprex (clevidipine butyrate) injectable emulsion for reducing BP when oral treatment is neither feasible nor desirable.
 

Lower BP Goal in Black CKD Patients

August 28, 2008

NEW ORLEANS—An extended follow-up of patients in the African American Study of Kidney Disease (AASK) confirms that ACE inhibitors work better than amlodipine in treating nondiabetic hypertensive CKD in black patients.
 

Beta Blocker Meets Stricter Criterion

August 25, 2008

NEW ORLEANS—Two pooled analyses of the newest beta blocker, nebivolol, demonstrate that it is effective as once daily monotherapy in stage 1 and 2 hypertension using more stringent criteria than normal to measure BP control.
 

Antihypertensive Agents Found to Slow GFR Decline

August 25, 2008

TORONTO—Patients treated with antihypertensive agents experience slower declines in renal function, new data show.
 

Very Elderly Benefit from BP Drugs

July 24, 2008

CHICAGO—In patients aged 80 years and older, antihypertensive treatment reduces morbidity and mortality according to results from the Hypertension in the Very Elderly (HYVET) trial.
 
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