Hyperphosphatemia

Study: Phosphate Binders Do Not Lower Death Risk

Study: Phosphate Binders Do Not Lower Death Risk

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Calcium-based binders, however, are associated with greater odds of all-cause mortality versus sevelamer.

Uncontrolled Phosphorus Linked to Poor Binder Adherence

Uncontrolled Phosphorus Linked to Poor Binder Adherence

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In a study, 61% of hemodialysis patients reported accidentally forgetting to take their medication or otherwise skipping doses unintentionally.

Natural Vitamin D Supplement Effective for Nondialysis CKD-MBD

Natural Vitamin D Supplement Effective for Nondialysis CKD-MBD

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Over 33 months, the 25-hydroxyvitamin D level of ergocalciferol recipients increased significantly from 15.14 to 37.32 ng/mL.

Low-Dose Niacin Helps Lower Phosphorus Levels

Low-Dose Niacin Helps Lower Phosphorus Levels

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Researchers evaluated the efficacy of 100 mg/day of niacin in hemodialysis patients.

Sucroferric Oxyhydroxide Exhibits a Dose-Dependent Effect

Sucroferric Oxyhydroxide Exhibits a Dose-Dependent Effect

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The phosphate binder is a useful treatment for hyperphosphatemia with a relatively low pill burden, researchers say.

Study: Minimal Risk of Iron Overload With Sucroferric Oxyhydroxide

Study: Minimal Risk of Iron Overload With Sucroferric Oxyhydroxide

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Patients may need no more than routine evaluation of iron.

Even High-Normal Phosphorus May Be an ESRD Risk Factor, Study Finds

Even High-Normal Phosphorus May Be an ESRD Risk Factor, Study Finds

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Phosphorus targets in patients with chronic kidney disease stage 3 to 4 should be below 4.3 mg/dL, researchers report.

Young Patients Often Misperceive Adherence to Phosphorus Control

Young Patients Often Misperceive Adherence to Phosphorus Control

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Hyperphosphatemia is present in many who say following diets and binder schedules is easy.

Patient Autonomy May Improve Phosphate Binder Adherence

Patient Autonomy May Improve Phosphate Binder Adherence

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Autonomy support could be an appropriate target for culturally informed strategies to optimize mineral bone health.

Calcium-based Phosphate Binders Linked to Higher Mortality

Calcium-based Phosphate Binders Linked to Higher Mortality

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A mortality rate increase of 43 cases per 1000 patients was found for calcium-based phosphate binders.

When Blood Is Sampled Affects Dialysis Patients' Phosphorus Values

When Blood Is Sampled Affects Dialysis Patients' Phosphorus Values

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Phosphorus levels are higher when blood specimens are collected after weekends.

Proposed Regimen May Cut Hypercalcemia Risk in CKD Patients

Proposed Regimen May Cut Hypercalcemia Risk in CKD Patients

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Paricalcitol-based protocol includes limited use of calcium-based phosphate binders.

Why SHPT Remains Difficult to Treat

Why SHPT Remains Difficult to Treat

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The control of phosphorus is underappreciated, for example.

Niacin's Phosphorus-Lowering Effect Confirmed

Niacin's Phosphorus-Lowering Effect Confirmed

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Average 6-month serum phosphorus level was significantly lower in CKD patients who received niacin than those who did not (3.4 vs. 4.2 mg/dL).

Iron-Based Binder Found to Improve Phosphorus Control, Cut Pill Burden

Iron-Based Binder Found to Improve Phosphorus Control, Cut Pill Burden

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Researchers observe an 81% increase in dialysis patients achieving recommended phosphorus levels after switching to sucroferric oxyhydroxide.

Multimodal Therapy for Calciphylaxis Shows Favorable Results

Multimodal Therapy for Calciphylaxis Shows Favorable Results

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Small case series also confirmed that the diagnosis of calciphylaxis is rarely made in the nodular, non-ulcerative phase.

Fixed-Dose Phosphate Binder Schedules May Be Less Than Ideal

Fixed-Dose Phosphate Binder Schedules May Be Less Than Ideal

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Study of peritoneal dialysis patients showed that they do not adjust binders to match the phosphate content of meals and snacks.

Personalized Diet Improves CKD-Related Risks

Personalized Diet Improves CKD-Related Risks

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A low protein diet of vegetable proteins along with reduced intake of specific micronutrients should be recommended to stage 3-4 CKD patients, researchers say.

Individual Variability Overlooked in Uncontrolled Hyperphosphatemia

Individual Variability Overlooked in Uncontrolled Hyperphosphatemia

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Expert suggests factors beyond poor adherence to a low phosphorus diet and binder therapy may contribute to hyperphosphatemia.

Phosphate Binders Show Similar Efficacy in African Americans

Phosphate Binders Show Similar Efficacy in African Americans

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Study compared sucroferric oxyhydroxide and sevelamer carbonate.

CKD Severity Linked to Low BMD, Hip Fracture, and Mortality

CKD Severity Linked to Low BMD, Hip Fracture, and Mortality

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The risk of dying following a hip fracture was 6.5 times higher for patients with severe CKD than for those with normal kidney function or mild CKD.

CKD-MBD May Play Role in Restless Legs Syndrome in Dialysis Patients

CKD-MBD May Play Role in Restless Legs Syndrome in Dialysis Patients

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Phosphate and vitamin D deficiency were linked with RLS severity.

High Phosphorus, Cerebral Hemorrhage Linked in HD Patients

High Phosphorus, Cerebral Hemorrhage Linked in HD Patients

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Researchers observe a 2.2-fold increased risk in patients with serum phosphate levels of 6.0 mg/dL or higher.

High Phosphate Increases Mortality Risk in CKD Patients

High Phosphate Increases Mortality Risk in CKD Patients

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Meta-analysis finds that each 1 mg/dL increase in serum phosphate increases the risk of death by 23%.

Sucroferric Oxyhydroxide Reduces Phosphorus, Binder Pill Burden

Sucroferric Oxyhydroxide Reduces Phosphorus, Binder Pill Burden

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Researchers observe a significant mean decrease in binder pills from 8.4 to 3.8 pills per day.

HD Patients with Lowest FGF-23 Level Have Lowest Survival Rate

HD Patients with Lowest FGF-23 Level Have Lowest Survival Rate

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Cumulative 2-year survival rate was 65.4%, 78.9%, 85.1%, and 80.6% among patients in the 1st, 2nd, 3rd, and 4th quartiles.

Stopping Cinacalcet for Non-Medical Reasons Ups Death Risk

Stopping Cinacalcet for Non-Medical Reasons Ups Death Risk

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About 3 additional deaths per 100 persons occur when the drug is discontinued due to non-medical versus medical reasons during the first year.

Ferric Citrate Reduces Hyperphosphate, EPO Requirement

Ferric Citrate Reduces Hyperphosphate, EPO Requirement

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Significant decreases in serum phosphate and erythropoietin dose in hemodialysis patients observed after 6 months of treatment.

Restricting Dietary Protein and Phosphorus May Improve CKD-MBD

Restricting Dietary Protein and Phosphorus May Improve CKD-MBD

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Very low protein intake was not superior to traditional low protein diets, however.

Nocturnal Dialysis Linked with Reduced Left Ventricular Mass

Nocturnal Dialysis Linked with Reduced Left Ventricular Mass

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Recipients of in-hospital nighttime dialysis experienced a 14.2 gram reduction in left ventricle thickening.

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