Hyperphosphatemia

Phosphorus Changes Affect Dialysis Patient Mortality Risk

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Declines in serum phosphorus over time may improve survival.

Higher PTH and Dietary Protein Intake Hikes Hyperphosphatemia Risk

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Worsening or resistant hyperphosphatemia may be an under-appreciated consequence of secondary hyperparathyroidism.

Phosphate Binders Offer No Short-Term Mortality Benefit

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Calcium-based and non-calcium-based binder use were associated with similar death risks.

Limiting Phosphorus Additives in Foods Lowers Serum Phosphorus

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Levels declined significantly from 7.2 to 5.0 mg/dL, data show.

Vascular Calcification Linked to Lower Phosphate Clearance

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Vascular calcification contributes to increased cardiovascular risk in dialysis patients.

Oxidative Stress May Be Why High Phosphorus Ups Mortality

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New findings are consistent with those from previous animal studies.

Novel Iron-Based Binder Has Long-Term Efficacy

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PA21 comparable in safety and efficacy to sevelamer carbonate out to 52 weeks, study finds.

Fasting Phosphorus Levels Are a Stronger Mortality Predictor

Fasting Phosphorus Levels Are a Stronger Mortality Predictor

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Serum levels vary throughout the day, and higher phosphorus intake exaggerates the early afternoon rise in serum phosphorus.

Race May Affect Phosphorus-Mortality Link in CKD Patients

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New findings raise questions "on the generalizability of previous research studies to the clinic setting," researchers conclude.

High Phosphorus Ups Dialysis Patient Death Risk Regardless of Age

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Low phosphorus increases all-cause and cardiovascular mortality only among the elderly.

Women's Phosphorus Levels Affected by Estrogen

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Phosphorus levels are lower in postmenopausal women on estrogen replacement therapy.

Calcium-Based Phosphate Binders Up Death Risk

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Patients who take phosphate binders may be at a 22% higher risk of death that those who take other non-calcium based treatments.

Phosphate Binders Improve Dialysis Patient Survival

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Use of the agents is associated with a 29% and 22% decreased risk of all-cause and cardiovascular mortality.

Food Additives May Hinder Phosphorus Control in CKD Patients

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A high proportion of top-selling grocery items contain phosphorus additives, and consumption may be encouraged by their lower cost.

Dialysis Patient Death Risk Lower with Sevelamer

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It significantly decreased cardiovascular and all-cause mortality compared with calcium carbonate.

Dialysis Patients Struggle to Restrict Dietary Phosphorus

Dialysis Patients Struggle to Restrict Dietary Phosphorus

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The increasing popularity of processed convenience foods could be a factor.

Heart Abnormality Tied to High Dietary Phosphorus Intake

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Consuming too much phosphorus increases the risk of left ventricular hypertrophy in women, study finds

Intradialytic High Protein Meals May Correct Low Albumin

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Combined with use of a binder, this approach raised serum albumin while maintaining target phosphorus levels.

Low BMI, Lipid Abnormalities Linked to High FGF-23

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Factors unrelated to mineral metabolism may contribute to the association between high FGF-23 and death in dialysis patients.

High Phosphorus Levels Increase Renal Failure Risk

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Researchers made the discovery in a study of individuals with normal kidney function.

Hyperphosphatemia Raises Proteinuria Risk in CKD Patients

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Proteinuria also is linked to high cholesterol.

Higher Phosphate Reduces VLPD Anti-Proteinuric Response

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Reducing phosphate burden may decrease proteinuria and slow progression of renal disease in patients with chronic kidney disease.

Side Effects Cited for Many Binder Discontinuations

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Nearly 11% of hemodialysis (HD) patients who discontinued use of a phosphate binder did so because of side effects.

Sodium Bicarbonate Lowers Phosphorus in PD Patients

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Oral sodium bicarbonate may ease hyperphosphatemia in peritoneal dialysis (PD) patients with metabolic acidosis.

Phosphorus and Disease Progression in Autosomal Dominant Polycystic Kidney Disease

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Dietary phosphorus may have an effect on the progression of autosomal dominant polycystic kidney disease.

Phosphorus Levels Lower in Elderly HD Patients

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Serum phosphorus concentrations are significantly lower in elderly hemodialysis (HD) patients compared with younger patients.

Give Priority to Phosphate Control, Researchers Conclude

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Phosphate level is a stronger predictor for increased mortality among hemodialysis (HD) patients than calcium and parathyroid hormone (PTH) levels.

Phosphate Binder, Phosphate Diet Act Synergistically

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Lanthanum carbonate acts in synergy with dietary phosphate restriction to decrease levels of fibroblast growth factor 23 (FGF-23) in patients with chronic kidney disease (CKD) and normal phosphate levels.

Higher Phosphate, PTH Predict Worse Outcomes

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Hyperparathyroidism develops prior to significant hyperphosphatemia in patients with chronic kidney disease (CKD) but not on dialysis.

Optimal Levels of PTH and Phosphorus Defined

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New findings presented at Kidney Week 2012 suggest that target serum phosphorus levels in patients on maintenance hemodialysis (MHD) may need to be defined.

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