Study of peritoneal dialysis patients showed that they do not adjust binders to match the phosphate content of meals and snacks.
A low protein diet of vegetable proteins along with reduced intake of specific micronutrients should be recommended to stage 3-4 CKD patients, researchers say.
Expert suggests factors beyond poor adherence to a low phosphorus diet and binder therapy may contribute to hyperphosphatemia.
Study compared sucroferric oxyhydroxide and sevelamer carbonate.
The risk of dying following a hip fracture was 6.5 times higher for patients with severe CKD than for those with normal kidney function or mild CKD.
Phosphate and vitamin D deficiency were linked with RLS severity.
Researchers observe a 2.2-fold increased risk in patients with serum phosphate levels of 6.0 mg/dL or higher.
Meta-analysis finds that each 1 mg/dL increase in serum phosphate increases the risk of death by 23%.
Researchers observe a significant mean decrease in binder pills from 8.4 to 3.8 pills per day.
Cumulative 2-year survival rate was 65.4%, 78.9%, 85.1%, and 80.6% among patients in the 1st, 2nd, 3rd, and 4th quartiles.
About 3 additional deaths per 100 persons occur when the drug is discontinued due to non-medical versus medical reasons during the first year.
Significant decreases in serum phosphate and erythropoietin dose in hemodialysis patients observed after 6 months of treatment.
Very low protein intake was not superior to traditional low protein diets, however.
Recipients of in-hospital nighttime dialysis experienced a 14.2 gram reduction in left ventricle thickening.
Even healthy adults show evidence of abnormal bone metabolism.
Researchers find link in the non-dialysis population.
Large South Korean study demonstrates the association in individuals with normal kidney function.
Large European study identifies ranges of phosphorus, calcium, and parathyroid hormone levels with the lowest death risk.
African-American patients, however, had significantly higher intact parathyroid hormone levels, possibly due to lower 25-hydroxyvitamin D levels.
Every 1 mg/dL increase in serum phosphorus level was linked with 36% greater odds of kidney failure among non-dialysis CKD patients.
High phosphate levels are associated with 3.3-fold increased odds of 28-day in-hospital mortality.
In a study, 45% of hemodialysis patients internationally reported skipping phosphate binder pills at least once in the prior month.
Patients with hyperphosphatemia lowered their phosphorus levels with a dietitian's guidance or cash incentive.
Boiling sliced meat in a pressure cooker filled with soft water may be a promising way for dialysis patients to reduce phosphorus intake.
Study implicates dairy products, cereals, and grains containing inorganic phosphate additives.
Among the phosphate-containing medicinal products prescribed to chronic kidney disease patients, 76% may contain absorbable phosphate.
Baseline eGFR, higher phosphorus, proteinuria, and male gender, also are associated with an elevated risk of end-stage renal disease in patients with chronic kidney disease.
Proteinuria, hyperphosphatemia, anemia linked more rapid annual decline in eGFR.
Cutting back on dietary phosphorus in addition to taking phosphate binders achieved greater decreases in serum phosphate in PD patients.
A study found that 78% of popular drinks, from flavored waters to lemonades to iced teas, contain far more phosphorus than listed in nutritional databases.
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NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)