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 Hyperphosphatemia

Novel Iron-Based Phosphate Binder Effective, Well-Tolerated

May 11, 2012

NATIONAL HARBOR, Md.—An investigational iron-based phosphate binder is effective and well tolerated in hemodialysis (HD) patients with hyperphosphatemia, according to data presented at the National Kidney Foundation 2012 Spring Clinical Meetings.
 

Novel Tool May Help Dialysis Patients with Phosphorus Control

April 30, 2011

LAS VEGAS—A novel interactive Web-based phosphorus education tool may help to improve phosphorus control in dialysis patients, according to a report at the National Kidney Foundation's Spring Clinical Meetings.
 

Hyperphosphatemia and Anemia Risk Factors in Diabetic Nephropathy Patients

April 30, 2011

LAS VEGAS—Albumunuria, proteinuria, lower estimated glomerular filtration rate (eGFR) in patients with diabetic nephropathy are significantly associated with hyperphosphatemia and anemia, researchers reported at the National Kidney Foundation's Spring Clinical Meetings.
 

Study Finds No Link Between FGF-23 and Dietary Phosphorus

April 29, 2011

LAS VEGAS—Fibroblast growth factor 23 (FGF-23) is not significantly associated with dietary phosphorus or urinary phosphorus excretion, researchers reported at the National Kidney Foundation's Spring Clinical Meetings.
 

Lanthanum Carbonate Found to Bind Dietary Phosphorus Better than Sevelamer

April 28, 2011

LAS VEGAS—Lanthanum carbonate binds dietary phosphorus more effectively than sevelamer, researchers reported here at the National Kidney Foundation's Spring Clinical Meetings.
 

CKD Stage 3 Patients Benefit from Extended-Release Niacin

April 28, 2011

LAS VEGAS—New findings presented at the National Kidney Foundation's Spring Clinical Meetings confirm the phosphorus-lowering effects of extended-release niacin in fixed-dose combination with laropiprant (ERN-L) in dyslipidemic patients with stage 3 chronic kidney disease (CKD).
 

Crushed Lanthanum Carbonate an Option for HD Patients

March 14, 2011

Crushing lanthanum carbonate and mixing it with food can be an option for hemodialysis (HD) patients with hyperphosphatemia who are unable to chew or swallow whole tablets, researchers reported in Hemodialysis International (2011;15:95-99).
 

Novel Binder Lowers Phosphorus, LDL Cholesterol

January 24, 2011

An investigational calcium-free phosphate binder called colestilan is safe and effective for controlling phosphorus in dialysis patients, and it has no impact on calcium levels, researchers reported.
 

Parathyroid Hormone, Alkaline Phosphatase and Fibroblast Growth Factor 23

By Orlando M. Gutiérrez, MD January 01, 2011

The management of chronic kidney disease-mineral bone disorder (CKD-MBD) is central to the care of patients with kidney disease. Key to these efforts is the availability of clinically accessible biomarkers that can help distinguish between a wide variety of bone and mineral disturbances related to kidney failure.
 

Restricting Dietary Phosphate Confers No Survival Benefit

December 10, 2010

Prescribed dietary phosphate restriction, as practiced today, is not associated with improved survival among hemodialysis (HD) patients, according to a new study. In fact, it may even increase the risk of death.
 

Phosphate, FGF-23 Rise in PD Patients as Residual Renal Function Declines

November 20, 2010

Serum phosphate and fibroblast growth factor 23 (FGF-23) levels increase in incident peritoneal dialysis (PD) patients increase as residual renal function declines, according to researchers who presented their findings at Renal Week 2010 in Denver.
 

High Phosphorus May Predict Faster CKD Progression

November 20, 2010

High baseline serum phosphorus levels in CKD patients may predict an increased likelihood of renal disease progression and death, according to Italian investigators, who presented their findings at Renal Week 2010 in Denver.
 

Elderly Men with CKD Are at Greater Death Risk

November 20, 2010

Among elderly patients with CKD, female gender and lower estimated glomerular filtration rate (eGFR) predict a higher risk of progressing to end-stage renal disease (ESRD), whereas male gender and a history of peripheral vascular disease are associated with an increased likelihood of death, according to a study presented at Renal Week 2010 in Denver.
 

Niacin for Phosphorus Lowering Benefits Diabetics

November 19, 2010

Niacin treatment is known to lower phosphorus levels in patients with stage 5 CKD and hyperphosphatemia, but new findings show that this effect extends across a broad spectrum of renal function in patients with type 2 diabetes without stage 4 or 5 CKD, researchers reported at Renal Week 2010 in Denver.
 

High Phosphorus Raises Death Risk in Peritoneal Dialysis Patients

November 19, 2010

Hyperphosphatemia is associated with an increased six-year mortality risk in patients on chronic peritoneal dialysis (CPD), according to data shown at Renal Week 2010 in Denver.
 

Phosphate-Binder Choice Could Impact Missed Dialysis Sessions

November 19, 2010

Use of sevelamer rather than calcium-based calcium binders (CBBs) to treat hyperphosphatemia in dialysis patients is associated with a reduction in missed in-center dialysis treatments regardless of dialysis organization size, according to findings published in abstract form as part of Renal Week 2010 in Denver.
 

Novel Iron-Based Phosphate Binder Effective, Well Tolerated

November 18, 2010

An experimental iron-based phosphate binder is effective for treating hyperphosphatemia in hemodialysis (HD) patients, and is well tolerated, according to new data shown at Renal Week 2010 in Denver.
 

Focused Phosphorus Management Program Decreases Hyperphosphataemia in ESRD Patients

November 18, 2010

Tracy J. Mayne, PhD, DaVita Inc., Denver discusses his study on that found focused phosphorus management program decreases hyperphosphataemia in end stage renal disease patients.
 

Data Support Once-Daily Niacin for Phosphorus Lowering

November 18, 2010

Once-daily extended-release niacin (ERN) treatment lowers serum phosphorus levels in patients with normal renal function and dyslipidemia associated with the metabolic syndrome, according to a study presented at Renal Week 2010 in Denver.
 

Phosphate-Binder Treatment May Lower Mortality

October 19, 2010

Phosphate-binder therapy is associated with reduced mortality in men with non-dialysis-dependent CKD, a study found.
 

Chewing Gum Could Aid in Phosphorus Control

October 11, 2010

Chitosan gum could offer dialysis patients an inexpensive way to control phosphorus nonsystemically without adding to their daily pill burden.
 

Lanthaum Carbonate Better for Phosphorus Absorption

July 27, 2010

Mean net dietary phosphorus absorption is significantly lower after a single dose of lanthanum carbonate (LC) than after a single dose of sevelamer carbonate (SC), data suggest.
 

Phosphate Binder May Reduce the Number of Hospitalization Days

April 17, 2010

Using sevelamer instead of calcium-based binders (CBBs) to treat hyperphosphatemia in dialysis patients can significantly decrease the number of days of hospitalization.
 

Sevelamer Carbonate May Impair Calcitriol Bioavailability

April 17, 2010

Sevelamer carbonate significantly decreases the bioavailability of oral calcitriol when the two drugs are administered together, but lanthanum carbonate does not, show data presented at the National Kidney Foundation's 2010 Spring Clinical Meetings.
 

Fluid Intake with Phosphate Binders Quantified

April 17, 2010

The daily fluid intake with phosphate binder (PB) pills accounts for a significant portion of the daily fluid restriction in hemodialysis (HD) patients, suggest data presented at the National Kidney Foundation's 2010 Spring Clinical Meetings.
 

High Phosphorus Linked to Lower Pulse Pressure in Women with CKD

April 16, 2010

Higher serum phosphorus is associated with lower pulse pressure in women, but not men, with non-dialysis dependent CKD, according to researchers at the National Kidney Foundation's 2010 Spring Clinical Meetings.
 

Proton Pump Inhibitors May Improve Phosphate Control

April 16, 2010

Proton pump inhibitors (PPIs) taken concurrently with phosphate binders may increase phosphate control in hemodialysis (HD) patients, according to researchers who presented their data at the National Kidney Foundation's 2010 Spring Clinical Meetings..
 

Lanthanum Carbonate Rapidly Reduces Phosphorus Levels

April 16, 2010

Lanthanum carbonate rapidly reduces serum phosphorus levels in dialysis patients, according to an analysis of data from four clinical trials reported at the National Kidney Foundation's 2010 Spring Clinical Meetings.
 

Lanthanum Carbonate Provides Long-Term Phosphate Control

April 15, 2010

Lanthanum carbonate provides sustained long-term reduction of serum phosphorus in dialysis patients, according to a study presented at the National Kidney Foundation 2010 Spring Clinical Meetings.
 

Findings Stress the Need for Phosphorus Counseling of CKD Patients

April 15, 2010

The phosphorus content of a typical American diet significantly increases levels of fibroblast growth factor-23 (FGF-23), a pilot study suggests.
 

 

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