Hyperphosphatemia

Novel Iron-Based Phosphate Binder Effective, Well-Tolerated

Jody A. Charnow May 11, 2012

NATIONAL HARBOR, Md.—An investigational iron-based phosphate binder is effective and well tolerated in hemodialysis (HD) patients with hyperphosphatemia, according to data presented at the National Kidney Foundation 2012 Spring Clinical Meetings.

Novel Tool May Help Dialysis Patients with Phosphorus Control

Jody A. Charnow April 30, 2011

LAS VEGAS—A novel interactive Web-based phosphorus education tool may help to improve phosphorus control in dialysis patients, according to a report at the National Kidney Foundation's Spring Clinical Meetings.

Hyperphosphatemia and Anemia Risk Factors in Diabetic Nephropathy Patients

Jody A. Charnow April 30, 2011

LAS VEGAS—Albumunuria, proteinuria, lower estimated glomerular filtration rate (eGFR) in patients with diabetic nephropathy are significantly associated with hyperphosphatemia and anemia, researchers reported at the National Kidney Foundation's Spring Clinical Meetings.

Study Finds No Link Between FGF-23 and Dietary Phosphorus

Jody A. Charnow April 29, 2011

LAS VEGAS—Fibroblast growth factor 23 (FGF-23) is not significantly associated with dietary phosphorus or urinary phosphorus excretion, researchers reported at the National Kidney Foundation's Spring Clinical Meetings.

Lanthanum Carbonate Found to Bind Dietary Phosphorus Better than Sevelamer

Jody A. Charnow April 28, 2011

LAS VEGAS—Lanthanum carbonate binds dietary phosphorus more effectively than sevelamer, researchers reported here at the National Kidney Foundation's Spring Clinical Meetings.

CKD Stage 3 Patients Benefit from Extended-Release Niacin

Jody A. Charnow April 28, 2011

LAS VEGAS—New findings presented at the National Kidney Foundation's Spring Clinical Meetings confirm the phosphorus-lowering effects of extended-release niacin in fixed-dose combination with laropiprant (ERN-L) in dyslipidemic patients with stage 3 chronic kidney disease (CKD).

Crushed Lanthanum Carbonate an Option for HD Patients

Jody A. Charnow March 14, 2011

Crushing lanthanum carbonate and mixing it with food can be an option for hemodialysis (HD) patients with hyperphosphatemia who are unable to chew or swallow whole tablets, researchers reported in Hemodialysis International (2011;15:95-99).

Novel Binder Lowers Phosphorus, LDL Cholesterol

Jody A. Charnow January 24, 2011

An investigational calcium-free phosphate binder called colestilan is safe and effective for controlling phosphorus in dialysis patients, and it has no impact on calcium levels, researchers reported.

Parathyroid Hormone, Alkaline Phosphatase and Fibroblast Growth Factor 23

By Orlando M. Gutiérrez, MD January 01, 2011

The management of chronic kidney disease-mineral bone disorder (CKD-MBD) is central to the care of patients with kidney disease. Key to these efforts is the availability of clinically accessible biomarkers that can help distinguish between a wide variety of bone and mineral disturbances related to kidney failure.

Restricting Dietary Phosphate Confers No Survival Benefit

Tasheema Prince December 10, 2010

Prescribed dietary phosphate restriction, as practiced today, is not associated with improved survival among hemodialysis (HD) patients, according to a new study. In fact, it may even increase the risk of death.

Phosphate, FGF-23 Rise in PD Patients as Residual Renal Function Declines

Jody A. Charnow November 20, 2010

Serum phosphate and fibroblast growth factor 23 (FGF-23) levels increase in incident peritoneal dialysis (PD) patients increase as residual renal function declines, according to researchers who presented their findings at Renal Week 2010 in Denver.

High Phosphorus May Predict Faster CKD Progression

Jody A. Charnow November 20, 2010

High baseline serum phosphorus levels in CKD patients may predict an increased likelihood of renal disease progression and death, according to Italian investigators, who presented their findings at Renal Week 2010 in Denver.

Elderly Men with CKD Are at Greater Death Risk

Jody A. Charnow November 20, 2010

Among elderly patients with CKD, female gender and lower estimated glomerular filtration rate (eGFR) predict a higher risk of progressing to end-stage renal disease (ESRD), whereas male gender and a history of peripheral vascular disease are associated with an increased likelihood of death, according to a study presented at Renal Week 2010 in Denver.

Niacin for Phosphorus Lowering Benefits Diabetics

Jody A. Charnow November 19, 2010

Niacin treatment is known to lower phosphorus levels in patients with stage 5 CKD and hyperphosphatemia, but new findings show that this effect extends across a broad spectrum of renal function in patients with type 2 diabetes without stage 4 or 5 CKD, researchers reported at Renal Week 2010 in Denver.

High Phosphorus Raises Death Risk in Peritoneal Dialysis Patients

Jody A. Charnow November 19, 2010

Hyperphosphatemia is associated with an increased six-year mortality risk in patients on chronic peritoneal dialysis (CPD), according to data shown at Renal Week 2010 in Denver.

On The Forefront

Sickle Cell Trait and Medullary Renal Carcinoma

A 55-year-old Caucasian woman initially presented to one of Cleveland Clinic's regional outpatient urology clinics with gross hematuria and an obstructing right ureteral stone.