Hyperphosphatemia Features

The Medical Minute Calcium-Based Phosphate Binders Up Death Risk

Calcium-Based Phosphate Binders Up Death Risk

Patients who take phosphate binders may be at a 22% higher risk of death that those who take other non-calcium based treatments.

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Study Reveals Advantages of Non-Calcareous Phosphate Binders

Study Reveals Advantages of Non-Calcareous Phosphate Binders

Use of these agents is associated with a much lower incidence of hypercalcemia compared with the use of calcium carbonate or calcium acetate.

Ferric Citrate Controls Phosphorus, Cuts ESA Use

Ferric Citrate Controls Phosphorus, Cuts ESA Use

Over 52 weeks, the drug maintained hemoglobin levels while decreasing IV iron use in dialysis patients with anemia.

Insulin Resistance Linked to High Phosphorus in Maintenance Hemodialysis (MHD) Patients

Insulin Resistance Linked to High Phosphorus in Maintenance Hemodialysis (MHD) Patients

In adjusted analyses, serum phosphorus levels independently predicted glucose disposal rate.

Higher Phosphorus, Cardiovascular Disease (CVD) Not Linked in Kidney Disease (CKD) Patients

Higher Phosphorus, Cardiovascular Disease (CVD) Not Linked in Kidney Disease (CKD) Patients

Each 0.5 mg/dL increment in serum phosphorus associated with 58% increased odds of coronary heart failure (CHF).

Ferric Citrate Phosphate Binder Cuts Hospitalization Rates

Ferric Citrate Phosphate Binder Cuts Hospitalization Rates

Rates for infection-, gastrointestinal-, and cardiac-related adverse events are lower than with sevelamer carbonate or calcium acetate.

Plant-Based Phosphorus Best for Kidney Disease (CKD) Patients

Plant-Based Phosphorus Best for Kidney Disease (CKD) Patients

Plant-based diet had the lowest urinary phosphorus excretion, whereas an inorganic-based diet had the highest.

Extended Hemodialysis May Improve Phosphate Control

Extended Hemodialysis May Improve Phosphate Control

Researchers observe significant decline in serum phosphate levels with 6 hours vs. 4 hours of treatment.

Higher Phosphorus Levels Predict Increased Death Risk in Men

Higher Phosphorus Levels Predict Increased Death Risk in Men

No association between phosphorus levels and all-cause mortality in women.

Elevated Phosphorus Levels Raise Risk of Kidney Failure

Elevated Phosphorus Levels Raise Risk of Kidney Failure

Every 1 mg/dL increase in serum phosphorus was independently associated with a 36% increased relative risk of kidney failure.

Hyperphosphatemia Raises Coronary Artery Calcification (CAC) Risk in Peritoneal Dialysis

Hyperphosphatemia Raises Coronary Artery Calcification (CAC) Risk in Peritoneal Dialysis

Study of coronary artery calcification (CAC) risk also shows serum phosphorus levels associated with nutritional intake and dialysis adequacy.

Ferric Citrate Approved for Phosphorus Control in Chronic Kidney Disease (CKD) Patients

Ferric Citrate Approved for Phosphorus Control in Chronic Kidney Disease (CKD) Patients

In addition to reducing serum phosphorus levels to within the recommended range, ferric citrate increases iron stores.

Novel Binder Lowers Phosphate with Fewer Pills

Novel Binder Lowers Phosphate with Fewer Pills

In a study, PA21 was as efficacious as sevelamer carbonate, but patients taking PA21 had a lower pill burden and better adherence.

Elevated Phosphorus May Increase Death Risk

Elevated Phosphorus May Increase Death Risk

Researchers observed the association among individuals with serum phosphorus levels measured after fasting for 12 or more hours.

Hospitalization Costs Lower with Ferric Citrate

Hospitalization Costs Lower with Ferric Citrate

Use is associated with fewer hospitalizations versus sevelamer carbonate and calcium acetate.

Phosphorus Control Using PTH Tested

Phosphorus Control Using PTH Tested

In mice with and without CKD, phosphorus levels decreased by an average of 35% by 6 hours after injection with long-acting PTH.