Hyperkalemia

High, Low Potassium Levels Up In-Hospital Mortality

High, Low Potassium Levels Up In-Hospital Mortality

By

Study characterizes the link between admission potassium levels and in-hospital mortality overall and among CKD and CVD patients.

FDA Approves Removal of Boxed Warning for Hyperkalemia Drug

FDA Approves Removal of Boxed Warning for Hyperkalemia Drug

By

Updated label for patiromer now recommends the drug be taken at least 3 hours before or after other oral medications.

Novel Hyperkalemia Drug Has No Significant BP Effects Long-Term

Novel Hyperkalemia Drug Has No Significant BP Effects Long-Term

By

Sodium zirconium cyclosilicate treatment for 12 months had no clinically meaningful effects on systolic or diastolic pressure, study finds.

Hypo- , Hyperkalemia Linked to ESRD

Hypo- , Hyperkalemia Linked to ESRD

By

The risks of death from any cause were elevated by 22% and 31% for individuals with serum potassium levels of 5.5 mmol/L and 3.2 mmol/L, respectively, compared with 4.2 mmol/L.

Increased Potassium Intake Found Not to Raise Hyperkalemia Risk

Increased Potassium Intake Found Not to Raise Hyperkalemia Risk

By

Lack of association observed in study of hypertensive patients with normal renal function.

Improved Treatment Needed for Emergency Hyperkalemia

Improved Treatment Needed for Emergency Hyperkalemia

By

Newer potassium binders might have a role in treating the condition, according to a panel.

Patiromer Reduces Potassium While Modestly Raising Calcium

Patiromer Reduces Potassium While Modestly Raising Calcium

By

In patients with chronic kidney disease, the risk of a potential small rise in calcium absorption should be weighed against the risk of hyperkalemia.

Hyperkalemia Risk With Add-on MRA Confirmed

Hyperkalemia Risk With Add-on MRA Confirmed

By

Use of a mineralocorticoid receptor antagonist plus a renin-angiotensin-system inhibitor found to increase hyperkalemia risk 3-fold.

Evidence Poor for Restricting High-Potassium Foods

Evidence Poor for Restricting High-Potassium Foods

By

A plant-based diet might one day prove to be an option for kidney disease patients.

Hyperkalemia Risk May Be Higher With MRA-RAAS Inhibitor Combo

Hyperkalemia Risk May Be Higher With MRA-RAAS Inhibitor Combo

By

Add-on mineralocorticoid receptor antagonist therapy increased serum potassium by 0.4 mEq.

Hyperkalemia Drug Lowers Aldosterone

Hyperkalemia Drug Lowers Aldosterone

By

Study demonstrates a novel effect of patiromer treatment in hyperkalemic CKD patients

Hyperkalemia Increases Mortality Risk

Hyperkalemia Increases Mortality Risk

By

In a large study, high potassium levels were associated with a significant 24% increased risk of death compared with normal levels.

ACEIs, ARBs May Cut Peritoneal Dialysis Initiators' CV Risk

ACEIs, ARBs May Cut Peritoneal Dialysis Initiators' CV Risk

By

Researchers found a 16% lower risk for strokes, heart attacks, and death combined among patients who took ACEIs or ARBs.

Novel Hyperkalemia Drugs May Help Optimize Use of RAAS Inhibitors

Novel Hyperkalemia Drugs May Help Optimize Use of RAAS Inhibitors

By

High potassium levels associated with the use of renin-angiotensin-aldosterone system inhibitors limit their use in CKD patients.

Hyperkalemia More Likely in Sicker Elderly Patients

Hyperkalemia More Likely in Sicker Elderly Patients

By

As elderly patients age, the number of drugs they take that may cause hyperkalemia increases.

No Survival Advantage With Early Renal-Replacement Therapy in AKI

No Survival Advantage With Early Renal-Replacement Therapy in AKI

Mortality no different for early versus delayed strategy for patients with severe acute kidney injury.

Insulin Regimens Show Similar Effects in Emergency Hyperkalemia

Insulin Regimens Show Similar Effects in Emergency Hyperkalemia

By

Systematic review finds that 10 units of short-acting insulin given intravenously may be used in cases of acute hyperkalemia.

Hyperkalemia Less Common Among Blacks

Hyperkalemia Less Common Among Blacks

By

The association between potassium levels and mortality, however, was similar among races.

Optimal Dose of SPS for Mild Hyperkalemia Reported

Optimal Dose of SPS for Mild Hyperkalemia Reported

By

A single 60g oral dose of sodium polystyrene sulfonate found effective in lowering potassium without causing post-treatment hypokalemia.

Hyperkalemia After AMI Frequent, Potentially Dangerous

Hyperkalemia After AMI Frequent, Potentially Dangerous

By

In-hospital mortality risk was more than double among patients whose hyperkalemia persisted than those whose potassium levels normalized.

Hyperkalemia Common in Clinical Practice

Hyperkalemia Common in Clinical Practice

By

Treatment with angiotensin-converting enzyme inhibitors was most strongly associated with hyperkalemia.

Aliskiren/Enalapril Combo Results in More Harms in Heart Failure

Aliskiren/Enalapril Combo Results in More Harms in Heart Failure

The addition of aliskiren to enalapril led to more adverse events in patients with chronic heart failure without an increase in benefit.

Dietary Potassium Restriction in Hemodialysis Patients Questioned

Dietary Potassium Restriction in Hemodialysis Patients Questioned

By

Researchers argue that little evidence exists to support this approach to prevent hyperkalemia.

ACE Inhibitors, ARBs Comparable for Diabetic Retinopathy Patients

ACE Inhibitors, ARBs Comparable for Diabetic Retinopathy Patients

By

Study finds no significant difference in the rates of all-cause mortality, major cardiac events, and hospital admission with hyperkalemia or AKI.

Renal Impairment Plus TMP-SMX Ups Hyperkalemia Risk

Renal Impairment Plus TMP-SMX Ups Hyperkalemia Risk

By

Use of ACE inhibitors or angiotensin receptor blockers also boost likelihood of the electrolyte disorder, new study finds.

Low Potassium Dialysate Effective for Treating Hyperkalemia

Low Potassium Dialysate Effective for Treating Hyperkalemia

By

The need for this approach varies by season, researchers from Qatar report.

Study: Potassium Measures May Differ, Impact Hyperkalemia Care

Study: Potassium Measures May Differ, Impact Hyperkalemia Care

By

Serum potassium measurements were 0.62 mmol/L lower when analyzed by blood gas vs biochemistry.

Hyperkalemia Linked to Aldosterone Antagonist Use

Hyperkalemia Linked to Aldosterone Antagonist Use

By

Researchers identified the association in a cohort of older patients with reduced ejection fraction after acute myocardial infarction.

Weight-based Insulin in Hyperkalemia Results in Less Hypoglycemia

Weight-based Insulin in Hyperkalemia Results in Less Hypoglycemia

Less hypoglycemia for patients weighing less than 95 kg, with no impact on potassium lowering.

The Promise of the New Hyperkalemia Drugs

The Promise of the New Hyperkalemia Drugs

By

Renal & Urology News interviewed Matthew R. Weir, MD, director of the division of nephrology and professor of medicine at the University of Maryland School of Medicine in Baltimore.

Sign Up for Free e-newsletters