High-Fat Diet May Harm the Prostate

Share this article:

A new study provides more evidence that a high-fat diet is a potential cause of prostatic diseases, including benign prostatic hyperplasia and prostate cancer.

In a study of mice, Sanjay Gupta, MS, PhD, and colleagues found that high-fat diets appear to activate a protein complex—nuclear factor kappa B (NF-ĸB), which could lead to intraprostatic inflammation.

When non-obese mice were fed a high-fat diet for four, eight, and 12 weeks, they exhibited significant increases in NF-ĸB activation, prostate weight, and prostate expression of markers of oxidative stress and inflammation compared with mice fed a regular diet. The researchers reported their findings online in The Prostate.

Share this article:
You must be a registered member of RUN to post a comment.
close

Next Article in Benign Prostatic Hyperplasia (BPH)

More in Benign Prostatic Hyperplasia (BPH)

Sitting to Urinate Eases Lower Urinary Tract Symptoms (LUTS)

Sitting to Urinate Eases Lower Urinary Tract Symptoms ...

Sitting to urinate is associated with an improved urodynamic profile in lower urinary tract symptoms (LUTS).

Many Urologists Not Strictly Adhering to BPH/LUTS Guidelines

Many Urologists Not Strictly Adhering to BPH/LUTS Guidelines

Many urologists not uniformly adhering to AUA guidelines for the management of benign prostatic hyperplasia/lower urinary tract symptoms.

Moderate-to-Severe Lower Urinary Tract Symptoms (LUTS) Undertreated

Moderate-to-Severe Lower Urinary Tract Symptoms (LUTS) Undertreated

Only 10% of men aged 45-69 years who progress from no or mild to moderate or severe lower urinary tract symptoms are treated, study finds.