Hemodialysis

Calciphylaxis Risk Factors in Hemodialysis Patients Identified

Calciphylaxis Risk Factors in Hemodialysis Patients Identified

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Researchers linked the condition to warfarin use, diabetes, obesity, recurrent skin trauma, and derangements in mineral metabolism.

Hyperkalemia After AMI Frequent, Potentially Dangerous

Hyperkalemia After AMI Frequent, Potentially Dangerous

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In-hospital mortality risk was more than double among patients whose hyperkalemia persisted than those whose potassium levels normalized.

ACEI/ARBs Improve AMI Outcomes Regardless of Kidney Function

ACEI/ARBs Improve AMI Outcomes Regardless of Kidney Function

Treatment linked to improved long-term survival, regardless of underlying kidney function.

Premature Tooth Loss Common Among ESRD Patients

Premature Tooth Loss Common Among ESRD Patients

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Findings from a small study suggest that periodontal disease may be a relevant contributing factor.

PTH Level Unrelated to Parathyroid Glands' Weight, Blood Flow

PTH Level Unrelated to Parathyroid Glands' Weight, Blood Flow

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Iranian study of hemodialysis patients with secondary hyperparathyroidism finds no significant correlation.

Subtotal and Total Parathyroidectomy Similarly Beneficial in SHPT

Subtotal and Total Parathyroidectomy Similarly Beneficial in SHPT

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Intact parathyroid hormone levels fell significantly in all patients who underwent total Ptx with autotransplant and 91.6% of subtotal Ptx patients.

Ablation Therapy Feasible for Secondary Hyperparathyroidism

Ablation Therapy Feasible for Secondary Hyperparathyroidism

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The non-surgical approach effectively lowered serum parathyroid hormone levels in the short term, but not to the same extent as surgery.

Cinacalcet Safe, Effective for Chinese HD Patients With Severe SHPT

Cinacalcet Safe, Effective for Chinese HD Patients With Severe SHPT

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A higher proportion of cinacalcet than placebo recipients met the primary efficacy endpoint of PTH levels of 250 pg/mL or less (25.4% vs. 3.5%).

Ferritin Levels Rising in Hemodialysis Patients

Ferritin Levels Rising in Hemodialysis Patients

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Trend is independent of intravenous iron use and exposure to erythropoiesis-stimulating agents.

Dietary Potassium Restriction in Hemodialysis Patients Questioned

Dietary Potassium Restriction in Hemodialysis Patients Questioned

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Researchers argue that little evidence exists to support this approach to prevent hyperkalemia.

CERA Safe, Effective in Patient Subgroups

CERA Safe, Effective in Patient Subgroups

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No new adverse events observed in patients with underlying cardiovascular risk factors who switched to continuous erythropoietin receptor activator.

Conservative Management Reasonable for Older Patients With ESRD

Conservative Management Reasonable for Older Patients With ESRD

Researchers suggest conservative care may be suitable option for some patients over 80.

Dialysis Bundling, ESA Labeling Changes Did Not Increase Mortality

Dialysis Bundling, ESA Labeling Changes Did Not Increase Mortality

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Observed rates of all-cause and cardiovascular mortality and myocardial infarction were consistent with expected rates, study shows.

Iron-Based Binder Found to Improve Phosphorus Control, Cut Pill Burden

Iron-Based Binder Found to Improve Phosphorus Control, Cut Pill Burden

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Researchers observe an 81% increase in dialysis patients achieving recommended phosphorus levels after switching to sucroferric oxyhydroxide.

Low Testosterone Associated with Higher Death Risk in Male Dialysis Patients

Low Testosterone Associated with Higher Death Risk in Male Dialysis Patients

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Study also identifies clinical characteristics associated with testosterone deficiency in this population.

Intradialytic Hypotension Hikes Long-Term Death Risk

Intradialytic Hypotension Hikes Long-Term Death Risk

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The condition is independently associated with a 60% increased risk of 5-year mortality in maintenance hemodialysis patients.

Peritoneal Dialysis Outpacing Home Hemodialysis

Peritoneal Dialysis Outpacing Home Hemodialysis

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Trend started around the introduction of the Medicare prospective payment system for dialysis care.

Racial Disparity in Survival Found in Pediatric Dialysis Patients

Racial Disparity in Survival Found in Pediatric Dialysis Patients

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African-American children are 64% more likely to die than white children.

Good Residual Renal Function Improves HD Patient Outcomes

Good Residual Renal Function Improves HD Patient Outcomes

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Researchers observe significantly higher levels of albumin and hemoglobin and better calcium and phosphate metabolism.

Low Potassium Dialysate Effective for Treating Hyperkalemia

Low Potassium Dialysate Effective for Treating Hyperkalemia

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The need for this approach varies by season, researchers from Qatar report.

Hemodialysis Patients Show Cognitive Impairment

Hemodialysis Patients Show Cognitive Impairment

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Meta-analysis reveals especially poor scores in attention and memory on neuropsychological tests.

Abrupt Pre-Dialysis Kidney Function Decline Predicts Early Death

Abrupt Pre-Dialysis Kidney Function Decline Predicts Early Death

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Study finds a 3-folder greater risk of early death within a year of hemodialysis initiation.

Multimodal Therapy for Calciphylaxis Shows Favorable Results

Multimodal Therapy for Calciphylaxis Shows Favorable Results

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Small case series also confirmed that the diagnosis of calciphylaxis is rarely made in the nodular, non-ulcerative phase.

Twice-Weekly Dialysis May Preserve Residual Kidney Function

Twice-Weekly Dialysis May Preserve Residual Kidney Function

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Patients with preserved residual kidney function experience a survival benefit.

Caution Urged In the Use of Megestrol

Caution Urged In the Use of Megestrol

Use of oral megestrol acetate (MA) is associate with significant adverse effects.

Infection Control Lapses in Dialysis Can Lead to HCV

Infection Control Lapses in Dialysis Can Lead to HCV

Dialysis providers and facilities should assess and improve infection control practices.

Factors Influencing the Timing of Dialysis Initiation

Factors Influencing the Timing of Dialysis Initiation

Factors include care practices of physicians, sources of momentum, patient-physician interactions.

Investigational Agent Shows Promise for SHPT in Hemodialysis Patients

Investigational Agent Shows Promise for SHPT in Hemodialysis Patients

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In a phase 2 trial, etelcalcitide, a novel peptide agonist of the calcium-sensing receptor, significantly reduced parathyroid hormone levels.

Earlier ESA Initiation May Improve Renal Outcomes

Earlier ESA Initiation May Improve Renal Outcomes

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Study shows benefit of initiating epoetin beta therapy at hemoglobin levels not less than 10 g/dL in non-dialysis CKD patients.

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