Gout

Gout Runs in the Family

Gout Runs in the Family

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Individuals with first-degree relatives affected by the condition are twice as likely as those in the general population to experienced gout.

Curbing Fructose Intake May Decrease Elevated Uric Acid

Curbing Fructose Intake May Decrease Elevated Uric Acid

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Elevated uric acid levels are associated with increased risks for hypertension, gout, and renal impairment.

No Gout Relieve From Vitamin C

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Patients with gout experienced no clinically significant urate-lowering effects from an 8-week course of a modest dosage of vitamin C.

Uric Acid and the Kidney - Is There a Role for Urate Lowering?

Uric Acid and the Kidney - Is There a Role for Urate Lowering?

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Many but not all cohort studies examining the relationship between hyperuricemia and CKD outcomes suggest they may be intertwined.

Allopurinol-Induced AEs Linked to Colchicine, Statin Use

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Adverse events included skin rash, gastrointestinal problems, and allopurinol hypersensitivity syndrome.

Gout Discovered in 30% of Patients with Severe CKD

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Gout prevalence is higher among patients with lower average estimated glomerular filtration rates or higher levels of albuminuria

Hypertension Increases Gout Risk

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The two are linked regardless of gender, race, and obesity.

Study: Cherries Lower Gout Attack Risk

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An consumption over a two-year period found to decrease likelihood of a gout attack by 35%.

Study: Gout Affects 4% of Americans

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Data from 5,707 participants of the National Health and Nutrition Examination Survey (NHANES) 2007-2008 show that gout now affects 4% of Americans (8.3 million individuals), and hyperuricemia, 21% (43.3 million).

Part III: Clinical Challenges and Renal Considerations in Managing Gout

A case study involving a 58-year-old man with acute gout attacks and multiple ­comorbidities, including hypertension and hypercholesterolemia.

Part II: Clinical Challenges and Renal Considerations in Managing Gout

A case study involving a 65-year-old man with chronic kidney disease and acute attacks of pain, swelling, and erythema in the first metatarsophalangeal joint.

Renal Cysts More Common in Gout Patients

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Gout patients have an increased prevalence of simple renal cysts, and these cysts are associated with a decreased likelihood of kidney stone disease, according to Brazilian investigators.

Clinical Challenges and Renal Considerations In Managing Gout

A case study examines the treatment of hyperuricemia and gout in a 57-year-old postmenopausal renal transplant recipient with intermittent gout attacks.

A Nephrologic Perspective on the Management of Gout

A Nephrologic Perspective on the Management of Gout

Gout is increasingly recognized in patients with chronic kidney disease, but the proper dosing regimen for traditional agents has not been well-studied in this patient group.

Gout Prevalence High in CKD Patients

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PHILADELPHIA—Patients with chronic kidney disease (CKD) have a relatively high prevalence of gout compared with the general population, according to data presented at Kidney Week 2011.

Renal Disease, Diabetes Linked to Uric Acid

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CHICAGO—Uncontrolled serum uric acid in patients with gout is associated with an increased risk of developing kidney disease and diabetes, according to the findings of two studies presented at the American College of Rheumatology annual meeting.

Allopurinol Can Be Used Safely in Renal Transplant Patients on Azathioprine

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VANCOUVER, B.C.—Allopurinol can be prescribed safely to treat recurrent gout in renal transplant recipients who are receiving azathioprine, British researchers reported.

FDA Takes On Unapproved Single-Ingredient Colchicine

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The FDA has ordered a halt to the marketing of unapproved single-ingredient oral colchicine, a medication commonly used for the daily prevention of gout, to treat acute gout flare-ups, and for the treatment of familial Mediterranean fever.

Drug for Chronic Refractory Gout Approved

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Savient Pharmaceuticals, Inc., of East Brunswick, N.J., has received FDA clearance to market Krystexxa (pegloticase) as a treatment for chronic gout in adult patients refractory to conventional treatment.

Gout Drug Has Cardiac Benefit

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MUNICH, GERMANY—Allopurinol, a drug long used to treat gout, can cause regression of left ventricular hypertrophy (LVH) and improvement of endothelial dysfunction in CKD patients, a study found.

Gout Drug Helps CKD Patients

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Allopurinol, a drug used to treat gout, may slow progression of kidney disease in CKD patients, according to new findings scheduled to be published in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

Colchicine Formulation Cleared for Preventing Gout Flares

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Colcrys, a new colchicine formulation, has received marketing clearance for the prevention of gout flares.

Panel Recommends Approval of Drug for Refractory Gout

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The FDA's Arthritis Drugs Advisory Committee has recommended that Krystexxa (pegloticase) be approved for treating refractory chronic gout.

New Drug Cleared For Gout Patients

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A new oral medication that reduces serum uric acid levels has received FDA approval for treating hyperuricemia in patients with gout.

Data Support Prednisolone Use For Gout

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A short course of a corticosteroid could supplant nonsteroidal anti-inflammatory drugs (NSAIDs) as the medication of choice to treat gout, Dutch researchers suggest.

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