General News

Water Ablation for BPH Lessens Risk of Ejaculatory Dysfunction

Water Ablation for BPH Lessens Risk of Ejaculatory Dysfunction

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A novel approach called "Aquablation" provides results comparable to TURP, but with a decreased likelihood of retrograde ejaculation.

Point-of-Care Ultrasound Helps Detect Stones

Point-of-Care Ultrasound Helps Detect Stones

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Complication rates were no higher with point-of-care ultrasound than CT.

Surgery vs Radiation for High-Risk Prostate Cancer

Surgery vs Radiation for High-Risk Prostate Cancer

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Physicians who treat patients with high-risk prostate cancer remain uncertain as to the optimal treatment approach, in part due to difficulty in interpreting study data.

Tolvaptan Slows Renal Function Decline in Later-Stage ADPKD

Tolvaptan Slows Renal Function Decline in Later-Stage ADPKD

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Patients with autosomal dominant polycystic kidney disease treated with tolvaptan experienced a 35% decrease in the annual rate of decline in eGFR.

Phosphate Binder Reduces FGF23 in CKD Patients

Phosphate Binder Reduces FGF23 in CKD Patients

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Patients with non-dialysis chronic kidney disease and iron deficiency anemia treated with ferric citrate experienced significant declines in FGF23 regardless of change in serum phosphorus.

Hypertension, Diabetes at Hemodialysis Initiation Increasing

Hypertension, Diabetes at Hemodialysis Initiation Increasing

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From 1995 to 2015, the prevalence of hypertension and diabetes among patients starting hemodialysis increased from 67.9% to 87.6% and from 43.1% to 59.6%, respectively.

Post-Dialysis Survival Odds Better After CABG vs PCI

Post-Dialysis Survival Odds Better After CABG vs PCI

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US veterans who underwent coronary artery bypass grafting versus percutaneous coronary intervention prior to starting dialysis had a 28% lower risk of death.

Resistant Hypertension Ups Risks of Cardiovascular Events, ESRD

Resistant Hypertension Ups Risks of Cardiovascular Events, ESRD

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Study of U.S. veterans found that patients with resistant hypertension had 23%, 31%, and 144% higher risk of myocardial infarction, stroke, and end-stage renal disease, respectively.

In-Hospital Mortality Linked to High, Low Phosphorus

In-Hospital Mortality Linked to High, Low Phosphorus

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Admission serum phosphorus levels below 2.5 and 4.9 mg/dL and above are associated with increased odds of dying in the hospital.

Second-Line Enzalutamide May Benefit Some mCRPC Patients

Second-Line Enzalutamide May Benefit Some mCRPC Patients

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In a prospective study, mCRPC patients placed on enzalutamide after their disease progressed while on abiraterone therapy had a median radiographic progression-free survival of 8.1 months.

Stone Risk Greater In Wetter Climates

Stone Risk Greater In Wetter Climates

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New study may redefine the "stone belt" in the United States.

Dialysis Care in an Emergency: Lessons From Hurricane Harvey

Dialysis Care in an Emergency: Lessons From Hurricane Harvey

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Staff shortages and lack of medical records surface as problems.

Prostate Cancer Hormone Therapy Ups Cardiac Risks

Prostate Cancer Hormone Therapy Ups Cardiac Risks

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Exposure to androgen-deprivation therapy was associated with a nearly 2-fold increased risk of heart failure among men without pre-existing cardiovascular disease.

High Rates of Infective Endocarditis Found Among ESRD Patients

High Rates of Infective Endocarditis Found Among ESRD Patients

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Hemodialysis patients had higher rates of infective endocarditis than peritoneal dialysis and kidney transplant patients.

Overuse of Prostate Cancer Scans May Be Easing

Overuse of Prostate Cancer Scans May Be Easing

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Efforts by physician groups in recent years to discourage inappropriate use of radiologic imaging for the initial staging of men with newly diagnosed low-risk disease possibly paying off.

IMRT for Prostate Cancer Radiation Therapy Soars

IMRT for Prostate Cancer Radiation Therapy Soars

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Use of intensity-modulated radiation therapy for prostate cancer increased from 3.5% to 64% from 2002 to 2012.

Prostate Cancer Risk Lower in NSAID Users

Prostate Cancer Risk Lower in NSAID Users

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In a case-control study, men who had ever used non-steroid anti-inflammatory drugs had a 23% decreased risk of prostate cancer.

Prostate Cancer Active Surveillance Use Low, But Increasing

Prostate Cancer Active Surveillance Use Low, But Increasing

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Use of active surveillance for very low-risk prostate cancer rose from 11.6% of patients in 2010 to 27.3% in 2013, study finds.

Chronic Kidney Disease Raises Tinnitus Risk

Chronic Kidney Disease Raises Tinnitus Risk

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Tinnitus is 3-fold more likely to develop in patients with versus without chronic kidney disease, new study shows.

Proximal PSA Predicts Prostate Cancer Metastasis Risk

Proximal PSA Predicts Prostate Cancer Metastasis Risk

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PSA levels of 10 ng/mL or higher in men who have biochemically recurrent PCa after radical prostatectomy and a PSADT less than 12 months are at imminent risk for metastatic disease.

Intensive BP Control May Reduce Death Risk in CKD Patients

Intensive BP Control May Reduce Death Risk in CKD Patients

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Targeting and treating systolic blood pressure to a lower range was associated with a 14% decreased risk of death, meta-analysis shows.

Upfront Cabozantinib for Advanced RCC Improves Outcomes

Upfront Cabozantinib for Advanced RCC Improves Outcomes

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Cabozantinib reduced the risk of disease progression or death compared with sunitinib among patients with previously untreated advanced renal cell carcinoma.

Arteriovenous Fistulas Not Always the Best Option

Arteriovenous Fistulas Not Always the Best Option

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Despite low infection rates, AVFs have a high risk of maturation failure and abandonment.

Prostate Cancer Screening Saves Lives, New Analysis Shows

Prostate Cancer Screening Saves Lives, New Analysis Shows

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A European trial found a survival benefit from PCa screening and a US trial did not, but a new analysis finds that both trials provide compatible evidence that screening decreases PCa mortality.

Liraglutide Linked With Lower Diabetic Kidney Disease Risk

Liraglutide Linked With Lower Diabetic Kidney Disease Risk

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Liraglutide-treated patients were 22% less likely than placebo recipients to experience a composite outcome of renal events.

Study Finds No Link Between Marijuana Use and Kidney Function

Study Finds No Link Between Marijuana Use and Kidney Function

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No significant association found between marijuana use and change in estimated glomerular filtration rate or development of albuminuria.

Cancer Drug Slows ADPKD Cyst Growth, Study Finds

Cancer Drug Slows ADPKD Cyst Growth, Study Finds

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Bosutinib treatment was associated with a 66% decrease in the annual rate of kidney enlargement.

Urologist Ownership of IMRT Linked to Its Greater Use for PCa

Urologist Ownership of IMRT Linked to Its Greater Use for PCa

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Patients are more likely to receive intensity-modulated radiation therapy if they are managed by urology practices with an ownership interest in the modality, study finds.

Researchers: Iron-based Binders Best for Hyperphosphatemia

Researchers: Iron-based Binders Best for Hyperphosphatemia

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Of 7 phosphate binders, iron-based agents were optimal when efficacy and safety are considered.

Study: Cystectomy Complication Rate Not Improving

Study: Cystectomy Complication Rate Not Improving

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Researchers find no significant change in overall complication rate from 2010 to 2015, but hospital length of stay and need for transfusion have declined.

Cancer Patient Self-Reporting Reliable and Feasible, Studies Show

Cancer Patient Self-Reporting Reliable and Feasible, Studies Show

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Prostate cancer patients accurately report their comorbidities, and participants in cancer clinical trials report more adverse events than trial investigators.

Not All High-Risk Prostate Cancers Are the Same

Not All High-Risk Prostate Cancers Are the Same

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Men with 1 high-risk factor experience better outcomes following treatment than those with 2 or 3 high-risk factors, study finds.

Blacks Less Likely to Undergo Definitive Prostate Cancer Therapy

Blacks Less Likely to Undergo Definitive Prostate Cancer Therapy

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Study of men with intermediate- or high-risk prostate cancer finds facility-level racial disparity in use of definitive treatment.

Timing of PSA Nadir Post-RP Predicts Biochemical Recurrence Risk

Timing of PSA Nadir Post-RP Predicts Biochemical Recurrence Risk

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A detectable PSA nadir combined with shorter time to nadir after prostate cancer surgery is associated with a higher risk of biochemical recurrence.

Olfactory Deficits, Malnutrition Markers Linked in CKD, ESRD Patients

Olfactory Deficits, Malnutrition Markers Linked in CKD, ESRD Patients

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Pilot study suggests intranasal theophylline may be worth further investigation as a treatment.

For Treating Uremic Pruritus, Evidence is Strongest for Gabapentin

For Treating Uremic Pruritus, Evidence is Strongest for Gabapentin

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Except for gabapentin, evidence for 38 other treatments is weak and limited by small studies with a high risk of bias, new review finds.

Active Surveillance for Intermediate-Risk PCa May Be Unsafe

Active Surveillance for Intermediate-Risk PCa May Be Unsafe

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Nearly 1 in 3 patients diagnosed with Gleason 3+4 favorable intermediate-risk prostate cancer had their disease upgraded or upstaged at radical prostatectomy.

Proteomics Identifies CKD Predictors

Proteomics Identifies CKD Predictors

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The investigators assessed proteomic profiling of 80 proteins using a multiplex assay.

Women Less Likely to Initiate Hemodialysis With an AV Fistula

Women Less Likely to Initiate Hemodialysis With an AV Fistula

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The odds of starting hemodialysis with an arteriovenous fistula are 31% lower for women compared with men.

Erectile Dysfunction May Predict Development of Parkinson's Disease

Erectile Dysfunction May Predict Development of Parkinson's Disease

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A new study found a 52% higher risk for the future development of Parkinson's disease among men with erectile dysfunction.

Mortality Up for ER Patients Discharged With AKI

Mortality Up for ER Patients Discharged With AKI

Higher mortality was seen in association with an emergency department discharge with acute kidney injury vs no acute kidney injury.

Add-on Sevelamer Therapy May Improve Hemodialysis Patient Survival

Add-on Sevelamer Therapy May Improve Hemodialysis Patient Survival

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Use of sevelamer was associated with a 14% decreased risk of death compared with non-use.

Vasectomy Poses Minimal Risk of Prostate Cancer

Vasectomy Poses Minimal Risk of Prostate Cancer

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Researchers calculated that the absolute increase in lifetime risk of prostate cancer associated with vasectomy was just 0.6%.

Ferritin Spike Soon After Hemodialysis Initiation Ups Mortality Risk

Ferritin Spike Soon After Hemodialysis Initiation Ups Mortality Risk

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Up to a 49% higher risk of death observed in patients who had a 400 ng/mL increase in serum ferritin from baseline values compared with patients who had relatively stable ferritin levels.

Optimal Iron Status for Hemodialysis Patients Reported

Optimal Iron Status for Hemodialysis Patients Reported

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Japanese researchers conclude that a serum ferritin level below 90 ng/mL and TSAT of 20% or higher was optimal for achieving a hemoglobin level of 10 g/dL or higher.

Radical Prostatectomy Use for High-Risk Prostate Cancer Rises Sharply

Radical Prostatectomy Use for High-Risk Prostate Cancer Rises Sharply

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Over a 10-year period, radical prostatectomy use increased steadily while radiotherapy use declined

Prostatic Urethral Lift Benefits Durable Out to 5 Years

Prostatic Urethral Lift Benefits Durable Out to 5 Years

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Patients who underwent the minimally invasive procedure had a 36%, 50%, and 44% improvement in IPSS, quality of life, and peak flow rate, respectively, at 5 years.

Prostate Atrophy, Inflammation Associated With Lower PCa Risk

Prostate Atrophy, Inflammation Associated With Lower PCa Risk

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Both findings on biopsy also predict a lower odds of high-grade cancer.

Symptomatic Bladder Cancer Recurrence Linked With Worse Survival

Symptomatic Bladder Cancer Recurrence Linked With Worse Survival

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Symptomatic recurrence was associated with a nearly 2-fold higher risk of death from the time of recurrence versus surveillance-detected recurrence.

Negative Confirmatory Biopsy a Good Sign in Prostate Cancer AS

Negative Confirmatory Biopsy a Good Sign in Prostate Cancer AS

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Prostate cancer patients on active surveillance who have no cancer found on confirmatory biopsy have a reduced risk of grade and volume reclassification.

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