General News

Kidney Stones Linked to Oral Antibiotics

Kidney Stones Linked to Oral Antibiotics

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Both younger age and more recent exposure to some antibiotics were associated with greater risks for kidney stones.

Smoking Ups Bladder Cancer Risk, Lowers Prostate Cancer Risk

Smoking Ups Bladder Cancer Risk, Lowers Prostate Cancer Risk

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Men and women who smoke are at 2.3-fold and 2.7-fold increased risk of bladder cancer compared with non-smokers.

Change in Red Blood Cell Distribution Width Tied With Mortality in HD

Change in Red Blood Cell Distribution Width Tied With Mortality in HD

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In a study, increases in red blood cell distribution width during the first year of dialysis was associated with greater risks for death.

What a Building Contractor Taught Me About Informed Consent

What a Building Contractor Taught Me About Informed Consent

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Identifying a patient's preferences and goals leads to a care plan that can reflect those goals, and this may improve patient satisfaction.

Predictors of Pediatric OAB Healing Time Identified

Predictors of Pediatric OAB Healing Time Identified

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Thicker bladder wall and a tower-shaped curve on uroflowmetry are associated with shorter healing periods among pediatric patients with overactive bladder.

Dusting vs Basketing During Ureteroscopy

Dusting vs Basketing During Ureteroscopy

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According to the EDGE Research consortium, both techniques should be in the armamentarium of the urologist.

ADPKD Linked to Lower Mortality in Peritoneal Dialysis Patients

ADPKD Linked to Lower Mortality in Peritoneal Dialysis Patients

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Among patients on peritoneal dialysis, the odds of death are 32% lower among those with vs without autosomal dominant polycystic kidney disease, meta-analysis finds.

Urea Found Safe and Effective for Hyponatremia

Urea Found Safe and Effective for Hyponatremia

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Treatment with a novel urea formulation that is available in the United States safely improves plasma sodium levels, small study shows.

ADPKD-Related Kidney Failure Occurs Earlier in Non-Hispanic Blacks

ADPKD-Related Kidney Failure Occurs Earlier in Non-Hispanic Blacks

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Among patients younger than 40, the prevalence of end-stage renal disease secondary to ADPKD was 9.94% among non-Hispanic blacks vs 7.68% among non-Hispanic whites.

More Extensive Lymph Node Dissection in PCa Improves Outcomes

More Extensive Lymph Node Dissection in PCa Improves Outcomes

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Study shows that the risk of recurrence after salvage radiotherapy is inversely related to the number of nodes resected at radical prostatectomy.

Outpatient AKI Is a Risk Factor for Death, Adverse Renal Outcomes

Outpatient AKI Is a Risk Factor for Death, Adverse Renal Outcomes

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In the most comprehensive study of its kind, investigators find that acute kidney injury not requiring hospitalization is associated with a 90% increased mortality risk.

Bladder Cancer Mortality in Men Lower With 5-ARI Use

Bladder Cancer Mortality in Men Lower With 5-ARI Use

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Use of 5-alpha-reductase inhibitors before and after diagnosis of the malignancy is associated with a 15% and 22% decreased risk of bladder cancer mortality, respectively.

Urgency Urinary Incontinence Linked to Previous Stroke

Urgency Urinary Incontinence Linked to Previous Stroke

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Individuals who had a stroke or transient ischemic attack at age 60 to 64 had a 2-fold higher risk of UUI at age 68 years, a British study found.

Single PSA Screening Has No Effect on Prostate Cancer Mortality

Single PSA Screening Has No Effect on Prostate Cancer Mortality

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Findings from a large study of men in the United Kingdom do not support single PSA testing for population-based screening.

Testosterone Replacement Therapy Does Not Raise CV Risks

Testosterone Replacement Therapy Does Not Raise CV Risks

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A large study of middle-aged men found that testosterone replacement therapy is associated with a small but significant decrease in cardiovascular risk and an increased risk of obstructive sleep apnea.

Meropenem-vaborbactam Superior for Complicated UTIs

Meropenem-vaborbactam Superior for Complicated UTIs

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Overall treatment success occurred in 98.4% of patients receiving meropenem-vaborbactam vs 94% for those receiving piperacillin-tazobactam.

Advanced CKD Linked to Worse Radical Cystectomy Outcomes

Advanced CKD Linked to Worse Radical Cystectomy Outcomes

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In multivariable analyses, CKD stage G3b or higher was significantly associated with worse progression-free and cancer-specific survival.

Higher-Dose IV Iron Appears Safe in Dialysis

Higher-Dose IV Iron Appears Safe in Dialysis

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Dialysis patients receiving more or less than 200 mg per month of IV iron had similar risks of death, infection, cardiovascular disease, and hospitalization, meta-analysis shows.

Children With CKD Have Lower IQs

Children With CKD Have Lower IQs

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One possible explanation is that increased plasma levels of uremic solutes resulting from kidney disease may impair synaptic development.

MRI May Help Cut Down on Unnecessary Prostate Biopsies

MRI May Help Cut Down on Unnecessary Prostate Biopsies

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Multiparametic MRI findings added to conventional clinical predictors decreases the number of false-positive biopsy results without increasing the number of clinically significant tumors left undiagnosed, study finds.

Anticoagulants Tied With Stroke, Hemorrhage in CKD

Anticoagulants Tied With Stroke, Hemorrhage in CKD

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Study questions the efficacy and safety of prescribing anticoagulants to older patients with atrial fibrillation and nondialysis chronic kidney disease.

Coronary Artery Calcification Risk Factors in CKD Identified

Coronary Artery Calcification Risk Factors in CKD Identified

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Abnormal calcium-phosphate metabolism appears to be an important pathogenic factor in the development of vascular calcification in patients with chronic kidney disease.

Pulmonary Hypertension Linked With Worse Prognosis in CKD, ESRD

Pulmonary Hypertension Linked With Worse Prognosis in CKD, ESRD

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Pulmonary hypertension in patients with any degree of renal insufficiency is associated with elevated risks of cardiovascular events and death.

Kidney Failure Associated With Low Albumin Levels

Kidney Failure Associated With Low Albumin Levels

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End-stage renal disease is more likely to develop in individuals with serum albumin levels of 4.1 g/dL or below than in those with levels of 4.4 g/dL or higher.

Adverse Prostate Cancer Pathology Accurately Predicted With MRI

Adverse Prostate Cancer Pathology Accurately Predicted With MRI

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Multiparametric MRI has high positive and negative predictive values for extracapsular extension, seminal vesicle invasion, lymph node involvement, and high-risk Gleason score.

Early Prostate Cancer Salvage ADT Therapy Better

Early Prostate Cancer Salvage ADT Therapy Better

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Among men who had PSA failure following radiation therapy for localized PCa, those with a long PSA doubling time had an increased risk of PCa mortality if they started androgen-deprivation therapy later.

Statin Use May Improve Survival in Advanced Prostate Cancer

Statin Use May Improve Survival in Advanced Prostate Cancer

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Statin use is associated with greater overall survival among men with metastatic castration-resistant prostate cancer and improved survival among patients with high-risk prostate cancer.

Kidney Failure, Death Tied With Elevated Uric Acid in CKD Patients

Kidney Failure, Death Tied With Elevated Uric Acid in CKD Patients

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In a study, CKD patients with high trajectories of serum uric acid had nearly triple the risk for ESRD and 4.5 times the risk for death.

Lymphoceles: A Contemporary Review and an Approach for Prevention

Lymphoceles: A Contemporary Review and an Approach for Prevention

Investigators have explored various strategies to prevent lymphoceles from forming.

CKD Patients With Heart Failure May Not Benefit From ICDs

CKD Patients With Heart Failure May Not Benefit From ICDs

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Study finds no difference in all-cause mortality among patients with chronic kidney disease and heart failure who received implantable cardioverter defibrillators and those who did not.

Kidney Stone Treatment Better With Ureterorenoscopy

Kidney Stone Treatment Better With Ureterorenoscopy

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For renal calculi 5 to 20 mm in diameter, treatment with flexible ureterorenoscopy was associated with higher stone-free and freedom from reintervention rates vs ESWL.

Ultra-low Contrast Volume May Protect Kidneys in Advanced CKD

Ultra-low Contrast Volume May Protect Kidneys in Advanced CKD

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No patient had a 25% or greater rise in serum creatinine 48 hours after receiving a median 13 mL of contrast for diagnostic coronary angiography, with an additional 13 mL for percutaneous coronary intervention.

Aspirin Found Effective for Erectile Dysfunction

Aspirin Found Effective for Erectile Dysfunction

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Erectile function among men with vasculogenic erectile dysfunction improved significantly after 6 weeks of treatment with an aspirin dosage of 100 mg/day.

Bladder Cancer Risk Higher in Urinary Stone Formers

Bladder Cancer Risk Higher in Urinary Stone Formers

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Patients with versus without a history of urinary calculi had nearly 2-fold greater odds of bladder cancer, meta-analysis showed.

Prostate Cancer Gene Testing Guidelines Issued

Prostate Cancer Gene Testing Guidelines Issued

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Clinicians need to ask about cancers among members of the maternal and paternal sides of a family.

Robotic Kidney Transplantation Safe, Feasible

Robotic Kidney Transplantation Safe, Feasible

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Robotic-assisted kidney transplantation is associated with a low complication rate and excellent graft function, European study shows.

PSA at 7 Months Prognostic in Treated mHSPC

PSA at 7 Months Prognostic in Treated mHSPC

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A study showed longer survival among patients with metastatic hormone-sensitive prostate cancer who achieved a PSA level of 0.2 ng/mL or less 7 months after initiating ADT.

Novel 3D Printed Prostates Could Improve Preoperative Planning

Novel 3D Printed Prostates Could Improve Preoperative Planning

New technique uses silicone-based polymer inks to create prostate models with the tactile sensation, pliability, and texture of a real prostate.

Some High-risk Heart Failure Patients Benefit From MRAs

Some High-risk Heart Failure Patients Benefit From MRAs

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Mineralocorticoid receptor antagonists found to lower hospital readmission risk in patients with heart failure and concomitant diabetes or renal insufficiency.

Partial Nephrectomy Improves Survival in cT1b RCC Cases

Partial Nephrectomy Improves Survival in cT1b RCC Cases

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Partial nephrectomy was associated with decreased odds of death versus radical nephrectomy among patients with cT1b but not cT2 renal cell carcinoma.

Shift Workers at Higher Risk for Prostate Cancer

Shift Workers at Higher Risk for Prostate Cancer

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A rotating shift schedule appeared the most risky.

Urologic Cancer Risk Higher in Kidney Failure Patients

Urologic Cancer Risk Higher in Kidney Failure Patients

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Patients with end-stage renal disease (ESRD) have a 6-fold and 4.4-fold increased risk of kidney cancer and urothelial cancers, respectively, than individuals without ESRD.

Optimal Salvage Treatment for Radiorecurrent PCa Still Unclear

Optimal Salvage Treatment for Radiorecurrent PCa Still Unclear

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Definitive comparative effectiveness data are lacking for salvage prostatectomy or salvage cryotherapy.

Calciphylaxis in CKD Patients Linked to Hypercoagulable Conditions

Calciphylaxis in CKD Patients Linked to Hypercoagulable Conditions

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In patients with stage 5 chronic kidney disease, lupus anticoagulant and combined thrombophilia occur more frequently in those with versus without calciphylaxis, case-control study shows.

Kidney Cancer Bone Metastasis Predictors Id'd

Kidney Cancer Bone Metastasis Predictors Id'd

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Levels of alkaline phosphatase, calcium, and hemoglobin can independently predict bone metastasis in patients with renal cell carcinoma, Chinese investigators report.

Residual Renal Function Not Linked to ESA Requirements

Residual Renal Function Not Linked to ESA Requirements

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Researchers find no significant difference in the median erythropoietin resistance index between patients with versus without residual renal function.

MRI Predicts Outcomes of Prostate Cancer Salvage Radiotherapy

MRI Predicts Outcomes of Prostate Cancer Salvage Radiotherapy

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A negative mpMRI is associated with a higher risk for PSA recurrence and metastasis following salvage radiotherapy for recurrent prostate cancer after radical prostatectomy.

Acute Kidney Injury in CCU Patients Linked to Cystatin C

Acute Kidney Injury in CCU Patients Linked to Cystatin C

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Among patients admitted to a coronary care unit, the highest quartile of serum cystatin C levels was associated with a 9.6-fold increased risk of AKI compared with the lowest quartile.

Structured Investigation of Outpatient Transperineal Prostate Biopsy

Structured Investigation of Outpatient Transperineal Prostate Biopsy

The transperineal approach to prostate biopsy has recently been adopted at many centers as an alternative to TRUS-B.

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