Injectable Drug for Advanced PCa Approved
This new gonadotropin-releasing hormone (GnRH) receptor inhibitor slows the progression of prostate cancer by suppressing testosterone. The efficacy of degarelix was established in a clinical trial of prostate cancer patients who received either degarelix or leuprolide, a current hormonal therapy.
Degarelix did not cause the temporary testosterone increase which is seen with some other drugs that affect GnRH receptors and can prompt a temporary growth in tumors. In fact, nearly all patients on either drug experienced suppression of testosterone to levels seen with surgical removal of the testes.