End-stage Renal Disease

Higher Cancer Risk in Dialysis Patients Confirmed

Higher Cancer Risk in Dialysis Patients Confirmed

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The risk is most elevated among individuals aged 44 years or younger.

CABG Better Than PCI in End-Stage Renal Disease

CABG Better Than PCI in End-Stage Renal Disease

Updated review and meta-analysis show beneficial effect for CABG for long-term mortality.

Smelling Ability Impaired in Renal Disease Patients

Smelling Ability Impaired in Renal Disease Patients

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Finding suggests that olfactory deficits may contribute to nutritional impairment in patients with chronic and end-stage renal disease.

The Looming Battle for ESRD Fountains

The Looming Battle for ESRD Fountains

As the rate of acceleration in ESRD incidence decline, physicians should expect heightened battles for the ESRD fountains.

Partial Nephrectomy Protects Against ESRD

Partial Nephrectomy Protects Against ESRD

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Nephron-sparing surgery decreased the risk of end-stage renal disease by 60% in select patients.

Premature Tooth Loss Common Among ESRD Patients

Premature Tooth Loss Common Among ESRD Patients

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Findings from a small study suggest that periodontal disease may be a relevant contributing factor.

Higher ESRD Risk in Blacks Not Due Solely to Genetic Variants

Higher ESRD Risk in Blacks Not Due Solely to Genetic Variants

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African Americans with and without a high-risk genotype experience similar kidney function decline.

Intensive Glucose Control May Result in Lasting ESRD Prevention

Intensive Glucose Control May Result in Lasting ESRD Prevention

In-trial reduction in risk of ESRD seen in ADVANCE trial persists after 9.9 years of follow-up.

Conservative Management Reasonable for Older Patients With ESRD

Conservative Management Reasonable for Older Patients With ESRD

Researchers suggest conservative care may be suitable option for some patients over 80.

CMS Uses CROWNWeb for Reporting Depression, Pain

CMS Uses CROWNWeb for Reporting Depression, Pain

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The end-stage renal disease community can now capture data on depression screening and pain assessment efforts.

Study Questions Blood Pressure Target for Diabetes Patients

Study Questions Blood Pressure Target for Diabetes Patients

A new large scale study found that depending on baseline systolic blood pressure (SBP) level, the use of antihypertensive medication led to different outcomes in patients with diabetes.

Statins Do Not Reduce Kidney Failure Risk

Statins Do Not Reduce Kidney Failure Risk

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Pre-dialysis CKD patients who took statins did experience a modest reduction in proteinuria and kidney function decline.

Adverse Renal Outcomes Linked to Blood Pressure Variability

Adverse Renal Outcomes Linked to Blood Pressure Variability

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Greater visit-to-visit variability in systolic blood pressure is associated with a higher risk of ESRD or a 50% or greater decrease in eGFR.

Abrupt Pre-Dialysis Kidney Function Decline Predicts Early Death

Abrupt Pre-Dialysis Kidney Function Decline Predicts Early Death

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Study finds a 3-folder greater risk of early death within a year of hemodialysis initiation.

ESRD Anemia Responds to Investigational Oral Drug

ESRD Anemia Responds to Investigational Oral Drug

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In a phase 2 trial, roxadustat maintained hemoglobin levels over 19 weeks as well as epoetin alfa.

Very Low-Protein Diet With Ketoanalogue May Slow CKD Progression

Very Low-Protein Diet With Ketoanalogue May Slow CKD Progression

Four patients would need to adhere to diet to avoid primary end point in per-protocol analysis.

Factors Influencing the Timing of Dialysis Initiation

Factors Influencing the Timing of Dialysis Initiation

Factors include care practices of physicians, sources of momentum, patient-physician interactions.

Online Tool Helps Predict ESRD in CKD Patients

Online Tool Helps Predict ESRD in CKD Patients

New risk calculator estimates who will need dialysis in 2 to 5 years.

Diabetic, Non-Diabetic ESRD Patients at High Risk for Hypoglycemia

Diabetic, Non-Diabetic ESRD Patients at High Risk for Hypoglycemia

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Severe hypoglycemia may result in changes in mental state, seizures, arrhythmias, coma, and death.

PSA Screening May Harm ESRD Patients Awaiting Transplant

PSA Screening May Harm ESRD Patients Awaiting Transplant

Screening not linked to improved patient survival after transplant; may delay time to listing, transplant.

PSA Screening May Harm ESRD Patients Awaiting Transplant

PSA Screening May Harm ESRD Patients Awaiting Transplant

Screening not linked to improved patient survival after transplant; may delay time to listing, transplant.

Current eGFR Better for ESRD Prediction

Current eGFR Better for ESRD Prediction

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It has a stronger association with future end-stage renal disease risk than past eGFR decline, large study shows.

Artificial Kidney Technology Moves Forward

Artificial Kidney Technology Moves Forward

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If ESRD patients face increasing difficulty getting a kidney transplant in coming years, they may see an artificial kidney as the next best alternative.

ACE Inhibitors May Be a Better Option for CKD Patients

ACE Inhibitors May Be a Better Option for CKD Patients

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The medications are associated with reduced odds of kidney failure and death compared with angiotensin II receptor blockers.

ESRD and Treatments May Raise Cancer Risk

ESRD and Treatments May Raise Cancer Risk

Dialysis, organ transplant may increase odds for certain types of cancer.

Long-Term Statin Therapy Improves Outcomes in CKD Patients With CAD

Long-Term Statin Therapy Improves Outcomes in CKD Patients With CAD

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Long-term statin treatment cut the rates of major adverse cardiovascular events by 20.5%, all-cause mortality by 28.6%.

Urinary Potassium Linked to Lower ESRD, CVD Risk in Diabetes

Urinary Potassium Linked to Lower ESRD, CVD Risk in Diabetes

Higher urinary potassium excretion, not sodium excretion, tied to lower risk of primary end point.

High Dietary Sodium, Potassium Raise CKD Progression Risk

High Dietary Sodium, Potassium Raise CKD Progression Risk

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Researchers also observe an increased risk of early death from any cause.

Lower Pre-ESRD Hemoglobin Predicts Better Dialysis Patient Survival

Lower Pre-ESRD Hemoglobin Predicts Better Dialysis Patient Survival

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Having hemoglobin 9-11 g/dL prior to dialysis provided the best life expectancy.

Higher Triglycerides Linked With Lower Mortality in Early Dialysis

Higher Triglycerides Linked With Lower Mortality in Early Dialysis

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Veteran patients with levels below 100 mg/dL had a 26% higher risk of mortality compared with patients with triglyceride levels of 150-200 mg/dL.

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