Diabetes

Early Menopause Might Up Type 2 Diabetes

Early Menopause Might Up Type 2 Diabetes

The researchers found that women who experienced premature menopause were 3.7 times more likely to develop diabetes.

Canagliflozin Delays Rise in Cardiovascular Biomarkers in Type 2 Diabetes

Canagliflozin Delays Rise in Cardiovascular Biomarkers in Type 2 Diabetes

The cardiac biomarker data provide support for the beneficial cardiovascular effect of sodium glucose co-transporter 2 inhibitors in T2DM.

Intensive Weight Loss in Diabetes Pts May Increase Frailty Fracture

Intensive Weight Loss in Diabetes Pts May Increase Frailty Fracture

Diabetes patients pursuing lifestyle interventions had a significantly increased risk of frailty fracture compared to diabetes support and education intervention patients.

CDC: More Than 100 Million US Adults Have Diabetes or Prediabetes

CDC: More Than 100 Million US Adults Have Diabetes or Prediabetes

Diabetes was seventh leading cause of death in 2015 in United States, according to report.

Coronary CT Helps Predict CV Events in Type 2 Diabetes

Coronary CT Helps Predict CV Events in Type 2 Diabetes

Addition of CCTA-detected obstructive coronary artery disease to risk factors ups prediction of MACE.

Insulin Degludec Tied With Fewer Hypoglycemic Episodes

Insulin Degludec Tied With Fewer Hypoglycemic Episodes

The rates of overall symptomatic hypoglycemia for insulin degludec vs insulin glargine were 185.6 vs 265.4 episodes per 100 PYEs.

Glycemic Control Improves With Hepatitis C Treatment

Glycemic Control Improves With Hepatitis C Treatment

Patients who achieved SVR had a greater drop in HbA1c associated with antiviral treatment than those who sustained treatment failure.

Hospitalizations for Heart Failure Decreasing in US

Hospitalizations for Heart Failure Decreasing in US

Between 2002 and 2013, heart failure hospitalizations declined by 30.8% nationwide, and continue to drop.

Tx Intensification Delayed in Many T2DM Pts With Elevated HbA1c

Tx Intensification Delayed in Many T2DM Pts With Elevated HbA1c

Therapeutic inertia was seen in 18.1% of the 12,730 patients with HbA1c of ≥8% at baseline or during follow-up.

Advanced Cancer Patients Ask for Secondary Germline Results

Advanced Cancer Patients Ask for Secondary Germline Results

The researchers found that 57% of participants expressed interest in learning their secondary germline findings, while 29% and 14%, respectively, were equivocal or disinterested.

Four Risk Factors Account for Most Heart Failure in A-Fib

Four Risk Factors Account for Most Heart Failure in A-Fib

The researchers found that new-onset AF correlated with increased risk of heart failure in multivariable models.

Early Loop Diuretic Linked With Fewer Deaths in Heart Failure

Early Loop Diuretic Linked With Fewer Deaths in Heart Failure

Earlier treatment remained significantly correlated with lower in-hospital mortality in multivariate analysis.

MACE Risk Similar With, Without Diabetes and No CAD

MACE Risk Similar With, Without Diabetes and No CAD

In a real-world population, patients with diabetes with high rates of statin and aspirin treatment had the same risk of cardiovascular events.

HbA1c Influenced by Race, Socioeconomic Factors

HbA1c Influenced by Race, Socioeconomic Factors

What's important is that doctors and other health-care providers, as well as patients, don't just assume these differences are normal and inconsequential.

Glucose Self-Monitoring Doesn't Improve HbA1c

Glucose Self-Monitoring Doesn't Improve HbA1c

The researchers found no differences between the groups in how well their blood glucose levels were controlled or in their quality of life.

Nasal Glucagon Effectively Treats Hypoglycemic Episodes

Nasal Glucagon Effectively Treats Hypoglycemic Episodes

In 96.2% of the episodes, blood glucose levels returned to normal within 30 minutes.

Insulin Degludec Noninferior to Glargine for CV Events in T2DM

Insulin Degludec Noninferior to Glargine for CV Events in T2DM

The researchers found that the primary outcome of first occurrence of an adjudicated major cardiovascular event occurred in 8.5% and 9.3% of patients in the degludec and glargine groups, respectively.

Canagliflozin Lowers Cardiovascular Risks in Type 2 Diabetes Patients

Canagliflozin Lowers Cardiovascular Risks in Type 2 Diabetes Patients

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Study findings suggest that the medication may offer renal protection.

Diabetic Ketoacidosis Risk Up With SGLT2 Inhibitors in T2DM

Diabetic Ketoacidosis Risk Up With SGLT2 Inhibitors in T2DM

The investigators found that patients taking SGLT2 inhibitors were approximately twice as likely to develop diabetic ketoacidosis than those taking DPP4 inhibitors.

Normal Meal Tolerance Test Useful for Type 2 Diabetes Management

Normal Meal Tolerance Test Useful for Type 2 Diabetes Management

The NMTT is a reliable insulin secretion test in patients with type 2 diabetes, except those in a hyperglycemic state.

National Diabetes Prevention Program Shows Early Success

National Diabetes Prevention Program Shows Early Success

Participants lost 0.3% of body weight for every additional program session attended and every 30 minutes of activity reported.

Step Count Rx Helps Patients Get More Fit

Step Count Rx Helps Patients Get More Fit

There was a net 20% steps/day increase in active vs. control arm participants.

FDA: Canagliflozin May Increase Risk of Foot, Leg Amputations

FDA: Canagliflozin May Increase Risk of Foot, Leg Amputations

Amputations of the toe and middle of the foot were the most common, but leg amputations below and above the knee also occurred.

PCSK9 Linked to New-Onset Diabetes After Kidney Transplantation

PCSK9 Linked to New-Onset Diabetes After Kidney Transplantation

NODAT occurred more frequently in the upper PCSK9 tertile vs the lowest two PCSK9 tertiles.

Diabetes Increases Penile Prosthesis Infection Risk

Diabetes Increases Penile Prosthesis Infection Risk

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Diabetic men receiving an inflatable penile prosthesis have a 69% increased risk of device-associated infection compared with non-diabetics.

Stone Formation Linked to Hemoglobin A1c Levels

Stone Formation Linked to Hemoglobin A1c Levels

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Finding could explain the association between obesity and diabetes and the development of kidney stones.

NODAT Risk Similar After Switching From CNIs to Everolimus

NODAT Risk Similar After Switching From CNIs to Everolimus

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The incidence of NODAT was 33.8% among patients who switched to everolimus and 36.4% among those who stayed on calcineurin inhibitors.

Diabetes Increases Post-Transplant Mortality Risk

Diabetes Increases Post-Transplant Mortality Risk

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In a study, diabetes in both the donor and recipient was associated with triple the risk of death at 5 years post-transplant compared with the absence of diabetes in both the donor and recipient.

Obesity Ups Diabetes Risk Among Living Kidney Donors

Obesity Ups Diabetes Risk Among Living Kidney Donors

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The adjusted 5-year risk of insulin use following donation is 5 times higher among obese vs normal weight donors.

Brief, Intensive Lifestyle and Drug Treatment Improves Type 2 Diabetes

Brief, Intensive Lifestyle and Drug Treatment Improves Type 2 Diabetes

A short course of intensive lifestyle and drug therapy achieves on-treatment normoglycemia and promotes sustained weight loss.

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