Diabetes

Greater Heart Disease Benefits From Yoga Aerobics Combo

Greater Heart Disease Benefits From Yoga Aerobics Combo

Greater improvement in CHD risk factors for combined intervention versus either alone.

Oral Semaglutide Increases Glycemic Control in Type 2 Diabetes

Oral Semaglutide Increases Glycemic Control in Type 2 Diabetes

Phase 3 studies next to assess longer-term/clinical outcomes, safety.

Oral Hypoglycemic Drugs With Insulin Lower HbA1c in Type 2 Diabetes

Oral Hypoglycemic Drugs With Insulin Lower HbA1c in Type 2 Diabetes

Adding sulfonylurea or metformin to insulin decreases HbA1c about 1

Case: Venovenous Hemodiafiltration Resolves Metformin Overdose

Case: Venovenous Hemodiafiltration Resolves Metformin Overdose

Case report describes treatment of female patient who attempted suicide with metformin overdose.

DPP4i Plus AGI Ups Glycemic Control in Type 2 Diabetes

DPP4i Plus AGI Ups Glycemic Control in Type 2 Diabetes

Greater drop in HbA1c with DPP4i added to alpha glucosidase inhibitor, with no increase in weight.

Insulin Dose Does Not Reflect Cardiovascular Events

Insulin Dose Does Not Reflect Cardiovascular Events

Similar findings among individuals with diabetes able to achieve normoglycemia.

Weight Loss Underappreciated for Type 2 Diabetes Remission

Weight Loss Underappreciated for Type 2 Diabetes Remission

Primary aim of diagetes management is lowering blood glucose or glycated hemoglobin (HbA1c) concentrations.

First-line Diabetes Rx Failure Attributed to Nonadherence

First-line Diabetes Rx Failure Attributed to Nonadherence

Second-line treatment often initiated without evidence of recommended use of first-line treatment.

Sensor-based Glucose Monitoring System Avoids Finger Pricks

Sensor-based Glucose Monitoring System Avoids Finger Pricks

Instead, sensor is implanted below skin in patients with diabetes.

Many Medicare Recipients Overtreated for Diabetes

Many Medicare Recipients Overtreated for Diabetes

Study of Medicare patients shows overtreatment for diabetes is rarely deintensified.

Anagliptin Improves LDL Partly Via ApoB-100 Suppression

Anagliptin Improves LDL Partly Via ApoB-100 Suppression

The results demonstrated a tendency for a decrease in LDL-C level at 24 weeks in the ANA group, and improvement was mediated through the suppression of apoB-100 synthesis.

Exenatide Does Not Increase Cardiovascular Risk in Type 2 Diabetes

Exenatide Does Not Increase Cardiovascular Risk in Type 2 Diabetes

Administration of exenatide in patients with type 2 diabetes at a wide range of cardiovascular risk appeared not to cause an increase in their overall cardiovascular risk.

2017 Standards of Medical Care in Diabetes Updated

2017 Standards of Medical Care in Diabetes Updated

This synopsis focuses on recommendations from the 2017 Standards of Care about monitoring and pharmacologic approaches to glycemic management for type 1 diabetes.

Diacerin Reduces HbA1c Levels in Type 2 Diabetes

Diacerin Reduces HbA1c Levels in Type 2 Diabetes

The researchers found that, compared with placebo, diacerein reduced HbA1c by 0.35% in the intention-to-treat analysis and by 0.41% in the per-protocol analysis.

Falling Insulin Requirement May Signal Placental Dysfunction

Falling Insulin Requirement May Signal Placental Dysfunction

Among pregnant women with FIR at 25, 30, and 36 weeks, the ratio of soluble fms-like tyrosine kinase 1 to placental growth factor was significantly higher.

Alcohol Consumption May Guard Against Diabetes

Alcohol Consumption May Guard Against Diabetes

Frequent consumption of alcohol is associated with the lowest risk of diabetes.

Even Slow Weight Gain Ups Hypertension, Diabetes, Cancer Risks

Even Slow Weight Gain Ups Hypertension, Diabetes, Cancer Risks

After 11 pounds gained, the risk of diabetes went up 31%, hypertension 14%, and cardiovascular disease 8%.

Liraglutide Linked With Lower Diabetic Kidney Disease Risk

Liraglutide Linked With Lower Diabetic Kidney Disease Risk

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Liraglutide-treated patients were 22% less likely than placebo recipients to experience a composite outcome of renal events.

Visceral to Subcutaneous Fat Ratio Predicts CVD in Diabetes

Visceral to Subcutaneous Fat Ratio Predicts CVD in Diabetes

The addition of V/S ratio to age, eGFR, BNP, antiplatelet agents, and HbA1c significantly improved classification performance for CVD.

Erectile Dysfunction Afflicts More Than Half of Men With Diabetes

Erectile Dysfunction Afflicts More Than Half of Men With Diabetes

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Meta-analysis of studies conducted around the world found that men with diabetes have more than 3.5 times increased risk for erectile dysfunction.

Early Menopause Might Up Type 2 Diabetes

Early Menopause Might Up Type 2 Diabetes

The researchers found that women who experienced premature menopause were 3.7 times more likely to develop diabetes.

Canagliflozin Delays Rise in Cardiovascular Biomarkers in Type 2 Diabetes

Canagliflozin Delays Rise in Cardiovascular Biomarkers in Type 2 Diabetes

The cardiac biomarker data provide support for the beneficial cardiovascular effect of sodium glucose co-transporter 2 inhibitors in T2DM.

Intensive Weight Loss in Diabetes Pts May Increase Frailty Fracture

Intensive Weight Loss in Diabetes Pts May Increase Frailty Fracture

Diabetes patients pursuing lifestyle interventions had a significantly increased risk of frailty fracture compared to diabetes support and education intervention patients.

CDC: More Than 100 Million US Adults Have Diabetes or Prediabetes

CDC: More Than 100 Million US Adults Have Diabetes or Prediabetes

Diabetes was seventh leading cause of death in 2015 in United States, according to report.

Coronary CT Helps Predict CV Events in Type 2 Diabetes

Coronary CT Helps Predict CV Events in Type 2 Diabetes

Addition of CCTA-detected obstructive coronary artery disease to risk factors ups prediction of MACE.

Insulin Degludec Tied With Fewer Hypoglycemic Episodes

Insulin Degludec Tied With Fewer Hypoglycemic Episodes

The rates of overall symptomatic hypoglycemia for insulin degludec vs insulin glargine were 185.6 vs 265.4 episodes per 100 PYEs.

Glycemic Control Improves With Hepatitis C Treatment

Glycemic Control Improves With Hepatitis C Treatment

Patients who achieved SVR had a greater drop in HbA1c associated with antiviral treatment than those who sustained treatment failure.

Hospitalizations for Heart Failure Decreasing in US

Hospitalizations for Heart Failure Decreasing in US

Between 2002 and 2013, heart failure hospitalizations declined by 30.8% nationwide, and continue to drop.

Tx Intensification Delayed in Many T2DM Pts With Elevated HbA1c

Tx Intensification Delayed in Many T2DM Pts With Elevated HbA1c

Therapeutic inertia was seen in 18.1% of the 12,730 patients with HbA1c of ≥8% at baseline or during follow-up.

Advanced Cancer Patients Ask for Secondary Germline Results

Advanced Cancer Patients Ask for Secondary Germline Results

The researchers found that 57% of participants expressed interest in learning their secondary germline findings, while 29% and 14%, respectively, were equivocal or disinterested.

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