Diabetes Linked to Increased Risk of Head and Neck Cancer
Retrospective cohort study in Taiwan shows significantly increased risk of cancer.
Patients newly diagnosed with diabetes have an increased risk of developing head and neck cancer, according to a study published online in JAMA Otolaryngology-Head & Neck Surgery.
Kuo-Shu Tseng, PhD, from the Tainan University of Technology in Taiwan, and colleagues used data from Taiwan's Longitudinal Health Insurance Research Database to examine the risk of head and neck cancer among patients with diabetes. A total of 89,089 patients newly diagnosed with diabetes and controls without diabetes and matched for comorbidities, sex, and age were included in the analyses.
Compared with the risk of a first malignant tumor in the control group, the incidence of head and neck cancer was 48% higher in patients newly diagnosed as having diabetes in adjusted analyses. Patients with diabetes had a significant 74%, 53%, and 40% increased risk of oral cancer, oropharyngeal cancer, and nasopharyngeal carcinoma, respectively, compared with controls.