Cystectomy

Radical Cystectomy Offers Better Survival vs Trimodal Therapy

Radical Cystectomy Offers Better Survival vs Trimodal Therapy

Bladder preservation for MIBC is associated with a higher mortality rate and greater costs compared with radical cystectomy.

Gender Difference in Survival Seen After Radical Cystectomy

Gender Difference in Survival Seen After Radical Cystectomy

Females have worse disease-free, cancer-specific, overall survival versus males with bladder cancer.

Neoadjuvant Chemo vs TUR Before RC Ups Survival

Neoadjuvant Chemo vs TUR Before RC Ups Survival

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Study findings suggest that clinicians should use neoadjuvant chemotherapy in many more muscle-invasive bladder cancer patients.

Aspirin Use Prior to Radical Cystectomy Linked to Improved Survival

Aspirin Use Prior to Radical Cystectomy Linked to Improved Survival

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Daily use of aspirin before radical cystectomy is associated with a significant 36% and 30% decreased risk of cancer-specific and all-cause mortality.

Advanced CKD Linked to Worse Radical Cystectomy Outcomes

Advanced CKD Linked to Worse Radical Cystectomy Outcomes

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In multivariable analyses, CKD stage G3b or higher was significantly associated with worse progression-free and cancer-specific survival.

Urologic Cancer Surgery Readmission Rate Highest for RC

Urologic Cancer Surgery Readmission Rate Highest for RC

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In a study, nearly 20% of radical cystectomy patients were readmitted for complications within 90 days compared with 1.9% and 5.9% for radical prostatectomy and radical nephrectomy, respectively.

Adjuvant Radiation Therapy May Improve Survival After Cystectomy

Adjuvant Radiation Therapy May Improve Survival After Cystectomy

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The locoregional recurrence-free survival rate at 2 years was significantly higher for patients treated with chemotherapy plus RT versus those treated with chemotherapy alone.

Preop Aerobic Exercise May Improve Cystectomy Outcomes

Preop Aerobic Exercise May Improve Cystectomy Outcomes

A feasibility study involving 60 patients with bladder cancer sought to determine if preoperative vigorous cardiovascular activity would improve postsurgical outcomes.

Trimodal Therapy and RC for MIBC Offer Similar Survival

Trimodal Therapy and RC for MIBC Offer Similar Survival

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Mean disease-specific survival at 10 years was 50.9% for TMT and 57.8% for RC patients, a non-significant difference.

COBRA Score Gauges Mortality Risk After Cystectomy

COBRA Score Gauges Mortality Risk After Cystectomy

Tool incorporates the relative contribution of tumor stage, lymph node involvement.

Bladder Preservation Therapy Linked With Reduced Survival in MIBC

Bladder Preservation Therapy Linked With Reduced Survival in MIBC

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Radical cystectomy is associated with better survival, but findings suggest BPT may produce acceptable oncologic outcomes in appropriately selected patients.

Study: Cystectomy Complication Rate Not Improving

Study: Cystectomy Complication Rate Not Improving

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Researchers find no significant change in overall complication rate from 2010 to 2015, but hospital length of stay and need for transfusion have declined.

Surgery, Combined Modality Offer Similar MIBC Outcomes

Surgery, Combined Modality Offer Similar MIBC Outcomes

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Meta-analysis reveals no significant difference in overall-, disease-specific, and progression-free survival between radical cystectomy and radiation-based, bladder preservation therapy.

MIBC Patients Should Be Followed Long-term After Cystectomy

MIBC Patients Should Be Followed Long-term After Cystectomy

After recurrent disease, 5-year overall survival was worse among patients with late recurrence.

Worse Survival After Robotic Cystectomy Seen at Low-Volume Centers

Worse Survival After Robotic Cystectomy Seen at Low-Volume Centers

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The researchers found lower overall survival among patients undergoing robot-assisted radical cystectomy at hospitals performing 10 or fewer procedures during 2010 to 2012.

Robot-assisted Radical Cystectomy on the Rise

Robot-assisted Radical Cystectomy on the Rise

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By 2014 to 2015, 1 in 3 bladder cancer surgical procedures performed in the United States were robot-assisted.

Radical Cystectomy for Muscle-invasive UCB Offers Better Survival

Radical Cystectomy for Muscle-invasive UCB Offers Better Survival

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Radical cystectomy is associated with better long-term overall survival than trimodal therapy, new study shows.

Pre-Cystectomy Chemo Does Not Up Survival in 'Real World' Setting

Pre-Cystectomy Chemo Does Not Up Survival in 'Real World' Setting

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Finding contrasts with results of randomized clinical trials.

Bladder Surgery Complications Predicted by New Model

Bladder Surgery Complications Predicted by New Model

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Nomograms specific to radical cystectomy currently do not exist to aid stratification of a patient's risks for complications.

Significant Prostate Cancer Found in Advanced Bladder Cancer Patients

Significant Prostate Cancer Found in Advanced Bladder Cancer Patients

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In a study, 53.1% of patients had concomitant prostate cancer in radical cystectomy specimens.

Tumor Features Predict Post-Cystectomy Recurrence

Tumor Features Predict Post-Cystectomy Recurrence

Predictors of distant recurrences after robot-assisted radical cystectomy were mainly dictated by pathological tumor characteristics.

New Study Supports Use of Trimodal Therapy for MIBC

New Study Supports Use of Trimodal Therapy for MIBC

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Researchers find no difference in 5-year disease-specific survival between multi-disciplinary bladder-sparing approach and radical cystectomy.

Early Recurrence After Laparoscopic Radical Cystectomy Explored

Early Recurrence After Laparoscopic Radical Cystectomy Explored

During first 24 months, 8.7% of patients with favorable pathological characteristics had progressed.

Cytoreductive RC Aids Survival of Metastatic Bladder Cancer Patients

Cytoreductive RC Aids Survival of Metastatic Bladder Cancer Patients

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Patients who underwent debulking had significantly longer overall survival compared with those who did not (median 15.7 vs 10 months).

Bladder Preservation Therapy for MIBC Predicts Worse Survival

Bladder Preservation Therapy for MIBC Predicts Worse Survival

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Mortality risk decreases with increasingly stringent BPT compared with radical cystectomy.

Gender Differences Found in Bladder Cancer Treatment, Survival

Gender Differences Found in Bladder Cancer Treatment, Survival

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Cancer-specific survival at 5 years was 76.9% for men and 71.5% for women.

Well-Timed Follow-Up Reduces Post-Cystectomy Readmissions

Well-Timed Follow-Up Reduces Post-Cystectomy Readmissions

The timing of office visits and telephone calls helped identify a patient at risk for readmission post-radical cystectomy.

Cutaneous Ureterostomy a Good Alternative for Elderly RC Patients

Cutaneous Ureterostomy a Good Alternative for Elderly RC Patients

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Shorter operating time is one advantage of cutaneous ureterostomy with a single stoma.

ASCO Endorses European Guideline on Bladder Cancer

ASCO Endorses European Guideline on Bladder Cancer

The guidelines were assessed for developmental rigor, and the ASCO endorsed all but one of the guidelines.

Readmission Due to Infection After Bladder Surgery Linked to Smoking

Readmission Due to Infection After Bladder Surgery Linked to Smoking

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Current smoking is independently associated with a greater than 2-fold increased odds of hospital readmission after radical cystectomy.

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