Contrast Nephropathy

High Incidence of Contrast-Induced Nephropathy Found

Jody A. Charnow January 15, 2010

Contrast-induced nephropathy (CIN) develops in 11% of emergency department patients who undergo contrast-enhanced CT (CECT), according to a study published in the Clinical Journal of the American Society of Nephrology (2009; published online ahead of print).

Sodium Bicarbonate Does Not Decrease CIN Risk

Jody A. Charnow October 16, 2009

A recent study shows that sodium bicarbonate is no better than saline in preventing contrast-induced nephropathy (CIN).

CIN May Have a Causal Role in Long-Term Adverse Events

Jody A. Charnow July 23, 2009

Evidence comes from a study comparing two strategies for preventing contrast-induced nephropathy

CIN Prevention Remains a Challenge

Sankar D. Navaneethan, MD, MPH April 07, 2009

Contrast-induced nephropathy (CIN), defined as a rise in serum creatinine greater than 0.5 mg/dL or a level greater than 25% from baseline following use of intravascular contrast media, is increasing.

Trial for Fluid Replacement System and CIN Prevention

William Weber January 22, 2009

PLC Medical Systems, Inc., of Franklin, Mass., has received full approval for a U.S. pivotal trial to study the effectiveness of its RenalGuard System and associated therapy in the prevention of contrast-induced nephropathy (CIN).

CIN Risk Similar With Iso- and Low-Osmolar Contrast

Alice Goodman July 21, 2008

CHICAGO—Iso-osmolar and low-osmolar contrast agents showed similar nephrotoxicity in a study of patients with impaired renal function undergoing percutaneous coronary intervention (PCI), according to findings presented here at the American College of Cardiology annual meeting.

CIN Rare After Chest Imaging Procedures

Alice Goodman July 21, 2008

CHICAGO—Routine use of contrast agents for evaluating chest pain carries a risk of contrast- induced nephropathy (CIN).

Targeted Renal Therapy May Stop CIN

John Schieszer July 15, 2008

WASHINGTON, D.C.—Targeted renal therapy (TRT) involving intrarenal administration of fenoldopam is safe and feasible in patients undergoing angiographic procedures, even in patients at elevated risk of suffering from contrast-induced nephropathy (CIN).

N -Acetylcysteine is Renoprotective

Jody A. Charnow May 05, 2008

A RECENT meta-analysis supports administration of N-acetylcysteine prophylaxis to prevent contrast-induced nephropathy, especially in high-risk patients. Researchers also noted that the drug is inexpensive and readily available, and has few side effects.

Pivotal Study Okayed for Nephropathy Prevention Device

William Weber May 01, 2008

PLC Systems Inc., of Franklin, Mass., has received conditional approval to begin enrollment in a pivotal trial to study the effectiveness of its RenalGuard Therapy and RenalGuard System in the prevention of contrast-induced nephropathy (CIN).

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