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Kidney Week 2014 Hyperphosphatemia Study Reveals Advantages of Non-Calcareous Phosphate Binders

Study Reveals Advantages of Non-Calcareous Phosphate Binders

Use of these agents is associated with a much lower incidence of hypercalcemia compared with the use of calcium carbonate or calcium acetate.

Kidney Week 2014 General News Kidney Cancer Linked to Kidney Stones

Kidney Cancer Linked to Kidney Stones

Meta-analysis reveals a significantly increased risk of kidney stones only in male patients with kidney cancer.

Kidney Week 2014 General News Calciphylaxis Risk Lower in Cinacalcet Users

Calciphylaxis Risk Lower in Cinacalcet Users

Calciphylaxis was 75% less likely to develop in patients who received the drug rather than placebo.

Kidney Week 2014 Anemia Ferric Citrate Controls Phosphorus, Cuts ESA Use

Ferric Citrate Controls Phosphorus, Cuts ESA Use

Over 52 weeks, the drug maintained hemoglobin levels while decreasing IV iron use in dialysis patients with anemia.

Kidney Week 2014 General News Diabetic Nephropathy More Common Than Previously Thought

Diabetic Nephropathy More Common Than Previously Thought

Researchers in the Netherlands report results from an autopsy study of diabetic nephropathy patients.

Kidney Week 2014 Hyperphosphatemia Insulin Resistance Linked to High Phosphorus in Maintenance Hemodialysis (MHD) Patients

Insulin Resistance Linked to High Phosphorus in Maintenance Hemodialysis (MHD) Patients

In adjusted analyses, serum phosphorus levels independently predicted glucose disposal rate.

Kidney Week 2014 Anemia ESA Use May Lower Risk of Transfusion

ESA Use May Lower Risk of Transfusion

Benefit seen among anemia and hemodialysis patients with hemoglobin levels below 10 g/dL.

Kidney Week 2014 Hyperphosphatemia Higher Phosphorus, Cardiovascular Disease (CVD) Not Linked in Kidney Disease (CKD) Patients

Higher Phosphorus, Cardiovascular Disease (CVD) Not Linked in Kidney Disease (CKD) Patients

Each 0.5 mg/dL increment in serum phosphorus associated with 58% increased odds of coronary heart failure (CHF).

Kidney Week 2014 General News Post-Op Acute Kidney Injury Not Prevented by Aspirin, Clonidine

Post-Op Acute Kidney Injury Not Prevented by Aspirin, Clonidine

Aspirin and clonidine increased the risk of major bleeding and clinically important hypotension in acute kidney injury (AKI).

Kidney Week 2014 Anemia Earlier Use of ESAs Benefits Non-Dialysis Kidney Disease (CKD) Patients

Earlier Use of ESAs Benefits Non-Dialysis Kidney Disease (CKD) Patients

Renal events are significantly less likely if erythropoiesis-stimulating agents are started at hemoglobin levels below 11 g/dL.

Kidney Week 2014 General News Tight Blood Pressure Control Benefits Some Polycystic Kidney Disease (ADPKD) Patients

Tight Blood Pressure Control Benefits Some Polycystic Kidney Disease (ADPKD) Patients

Tight blood pressure control slows the rate of increase in total kidney volume and reduces left ventricular index.

Kidney Week 2014 General News Severe Periodontal Disease Ups Kidney Disease (CKD) Risk in African Americans

Severe Periodontal Disease Ups Kidney Disease (CKD) Risk in African Americans

Periodontal disease is associated with a significant 4.2-fold greater incidence of chronic kidney disease (CKD).

Kidney Week 2014 Hyperphosphatemia Ferric Citrate Phosphate Binder Cuts Hospitalization Rates

Ferric Citrate Phosphate Binder Cuts Hospitalization Rates

Rates for infection-, gastrointestinal-, and cardiac-related adverse events are lower than with sevelamer carbonate or calcium acetate.

Kidney Week 2014 Anemia Giving Vitamin B6 Ups Resistance to ESAs

Giving Vitamin B6 Ups Resistance to ESAs

New finding on vitamin B6 is the opposite of what investigators hypothesized on patients with anemia.

Kidney Week 2014 Hyperphosphatemia Plant-Based Phosphorus Best for Kidney Disease (CKD) Patients

Plant-Based Phosphorus Best for Kidney Disease (CKD) Patients

Plant-based diet had the lowest urinary phosphorus excretion, whereas an inorganic-based diet had the highest.

Genitourinary Cancers Symposium Support for Adjuvant Chemotherapy in Nonmetastatic Bladder Cancer

Support for Adjuvant Chemotherapy in Nonmetastatic Bladder Cancer

Adjuvant chemotherapy is associated with better survival among patients with advanced nonmetastatic bladder cancer.

Genitourinary Cancers Symposium Low-dose Brachytherapy Provides Better Outcomes in Intermediate PCa

Low-dose Brachytherapy Provides Better Outcomes in Intermediate PCa

Low-dose-rate brachytherapy boost (LDR-PB) achieves better rates of biochemically disease-free outcomes in prostate cancer.

Genitourinary Cancers Symposium Short-Term ADT+Radiotherapy Does Not Help Intermediate PCa Survival

Short-Term ADT+Radiotherapy Does Not Help Intermediate PCa Survival

Adding short-term androgen deprivation therapy to radiotherapy does not improve overall survival in intermediate-risk prostate cancer.

Genitourinary Cancers Symposium Early Bicalutamide Aids Survival in Nonmetastatic Prostate Cancer

Early Bicalutamide Aids Survival in Nonmetastatic Prostate Cancer

Adding bicalutamide improves overall survival among patients with advanced nonmetastatic hormone-naïve prostate cancer.

Genitourinary Cancers Symposium Prostate Cancer Active Surveillance Outcomes Vary by Disease Risk

Prostate Cancer Active Surveillance Outcomes Vary by Disease Risk

Cancer-specific and overall survival is decreased in men with intermediate-risk versus low-risk tumors.

Genitourinary Cancers Symposium High BMI a Plus for Some Metastatic Kidney Cancer Patients

High BMI a Plus for Some Metastatic Kidney Cancer Patients

Overweight or obese patients treated with targeted therapy for metastatic clear-cell renal cell carcinoma found to live longer.

Genitourinary Cancers Symposium Statins May Prolong Life in Patients with Advanced Kidney Cancer

Statins May Prolong Life in Patients with Advanced Kidney Cancer

In a study of 4,736 patients with metastatic renal cell carcinoma, use of the drugs was associated with a nearly 22% decreased risk of death.

Genitourinary Cancers Symposium Adjuvant Kidney Cancer Drugs Fail to Improve Outcomes

Adjuvant Kidney Cancer Drugs Fail to Improve Outcomes

Sorafenib or sunitinib given after surgery for advanced renal cell carcinoma does not improve progression-free survival, study shows.

Genitourinary Cancers Symposium Statins Plus ADT After Prostate Cancer Radiotherapy Ups Survival

Statins Plus ADT After Prostate Cancer Radiotherapy Ups Survival

Researchers observed a significant 36% decreased overall and prostate cancer-specific mortality.

Genitourinary Cancers Symposium Identifying Urothelial Cancer Subtypes Matters

Identifying Urothelial Cancer Subtypes Matters

It has implications for treatment decisions and prognosis.

Genitourinary Cancers Symposium BCG + Sunitinib Promising for High-Risk Bladder Cancer

BCG + Sunitinib Promising for High-Risk Bladder Cancer

In a phase 2 trial, 72% of patients with high-grade clinical nonmuscle-invasive bladder cancer had a complete response at 3 months.

Genitourinary Cancers Symposium New Tool Could Spare Men Unnecessary Prostate Biopsies

New Tool Could Spare Men Unnecessary Prostate Biopsies

The 4Kscore enables better identification of men who harbor high-grade prostate cancer.

Genitourinary Cancers Symposium Radiation Plus ADT Beneficial in Node-Positive Prostate Cancer

Radiation Plus ADT Beneficial in Node-Positive Prostate Cancer

The 5-year risk of overall mortality is decreased by 50% compared with androgen deprivation therapy alone.

Genitourinary Cancers Symposium Better mCRPC Survival with Docetaxel Followed by Abiraterone

Better mCRPC Survival with Docetaxel Followed by Abiraterone

This medication sequence was associated with longer progression-free and overall survival compared with the reverse.

Genitourinary Cancers Symposium Genitourinary Cancer in Siblings Raises Personal Risk

Genitourinary Cancer in Siblings Raises Personal Risk

Researchers found elevated familial risks for testicular, prostate, bladder, and kidney cancers.

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