Expanding the Use of ECD Kidneys
Two articles in this issue relay new findings on one of the most pressing and controversial issues in nephrology: increasing the number of donor kidneys available for transplantation. The solution examined in each article is the use of more kidneys from expanded criteria donors (ECD).
The article beginning on page 1 describes an important paper presented during the American Society of Nephrology's recent Renal Week 2007 in
The second article (page 10) reports on three studies presented at the 13th Congress of the European Society for Organ Transplantation in
of conventional ECD kidneys and “extreme” ECD kidneys are associated with similar patient and graft survival. These similar outcomes, senior researcher Robert Stratta, MD, observed, suggest that the limits of acceptability for ECDs continue to expand.
ECD kidneys include organs from deceased donors over age 60 or those over age 50 with health conditions such as hypertension, stroke, or elevated creatinine levels. For the
Although these organs would not be the first choice for transplantation, they could come into much wider use if dire predictions about the end-stage renal disease (ESRD) population come true. In a study presented during Renal Week 2007, researchers projected that the number of ESRD patients in the
Moreover, a new study in the Journal of the American Medical Association by Joseph Coresh and his colleagues shows that the prevalence of CKD stages 1-4 in the