Daily Dose Thresholds: Sedatives-Hypnotics

DAILY DOSE THRESHOLDS: SEDATIVES-HYPNOTICS
Generic Brand Usual Max
Daily Dose
Max Daily
Dose for
LTC Patients
chloral hydrate* 2000mg  500mg
diphenhydramine* Benadryl   50mg   25mg
estazolam    2mg   0.5mg
eszopiclone Lunesta    3mg    1mg
flurazepam*   30mg   15mg
hydroxyzine* Vistaril  100mg   50mg
lorazepam Ativan    4mg    1mg
oxazepam   30mg   15mg
quazepam* Doral   15mg   7.5mg
ramelteon Rozerem    8mg    8mg
temazepam Restoril   30mg   15mg
triazolam* Halcion   0.5mg 0.125mg
zaleplon Sonata   20mg    5mg
zolpidem Ambien   10mg    5mg
Ambien CR 12.5mg  6.25mg
Intermezzo 1.75mg (female)
3.5mg (male)
 1.75mg

*Not recommended for management of insomnia, especially in elderly.

REFERENCES

Adapted from the CMS State Operations Manual: Appendix PP - Guidance to Surveyors for Long Term Care Facilities.
Available at: cms.hhs.gov/manuals/Downloads/
som107ap_pp_guidelines_ltcf.pdf
. Accessed 9/2010.

(Rev. 9/2014)

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