From the Cleveland Clinic

Neoadjuvant VEGF-Targeted Therapy in Renal Cell Carcinoma

Recent therapeutic advances in metastatic renal cell carcinoma (RCC) have included agents targeted against vascular endothelial growth factor (VEGF).

Bioartificial Kidney Meeting Research Milestones

A pioneering implantable artificial kidney developed jointly by teams of researchers at Cleveland Clinic, the University of California at San Francisco, and the University of Michigan in Ann Arbor is on track to meet project milestones in a pilot and feasibility study funded by the NIH.

Changes in the In-Hospital Dialysis Unit

The provision of in-hospital dialysis services over the next decade will necessitate a rethinking of the unit infrastructure.

Partial Nephrectomy for Larger Renal Masses

Partial nephrectomy has been the procedure of choice for patients with poor renal function, tumors in solitary kidneys or bilateral renal tumors.

How a 'Glomerulonephritis Board' Can Help Improve Patient Care

How a 'Glomerulonephritis Board' Can Help Improve Patient Care

Considering the advancement in the diagnosis and treatment of glomerular disease, we formed a Glomerulonephritis Board (GN Board) at Cleveland Clinic that brings together key medical specialists.

Optimal Use of the Electronic Medical Record in CKD

The electronic medical record (EMR) has enabled creation of a CKD registry, a database that contains demographic information, clinical parameters, and outcome measurements of more than 41,000 CKD patients who have received medical care within the Cleveland Clinic Health System since January 2005.

Redefining Hypertension for Tomorrow: Target Levels

There is sufficient evidence to demonstrate that lowering BP to less than 140/90 mm Hg offers cardiovascular and renal protection.

Magnetic Resonance Imaging of the Prostate

Prostate magnetic resonance (MR) provides high-resolution images of the prostate; seminal vesicles; and nearby pelvic organs and structures, including the bladder and rectum.

Kidney Function in Living Donors: Understanding Health Versus Disease

Data from 1,000 former kidney donors suggest that normal values of glomerular filtration rate decline with age.

First Completely Transvaginal Nephrectomy

First Completely Transvaginal Nephrectomy

Jihad Kaouk, MD, Director of the Center for Laparoscopic and Robotic Surgery, and his team performed the world's first completely transvaginal nephrectomy on March 13, 2009.

Effects of Smoke on Bladder Cancer Treatment

Last year, our lab team received a grant from the Flight Attendants Medical Research Institute (FAMRI). FAMRI was created from a settlement with tobacco companies over flight attendant exposure to secondhand smoke in their work.

Transobturator Sling for Post-Op Incontinence in Men

A urethral sling placed via a transobturator approach has recently emerged as a treatment option for men with mild-to-moderate postprostatectomy incontinence.

After the PSA Cutoff Era: The Importance of Context

About two years ago, having recognized that the prostate-specific antigen (PSA) cutoff level of 4.0 ng/mL did not always assist in accurately categorizing a man's risk for prostate cancer, we began to eliminate this—or any—artificial cutoff defining a "normal" PSA value.

Eric A. Klein, MD, Appointed Glickman Institute Chairman

Eric A. Klein, MD, Appointed Glickman Institute Chairman

Eric A. Klein, MD, a thought leader in the biology and management of prostate cancer, has been appointed chairman of the Glickman Urological & Kidney Institute.

Kidney Transplants in Nonrenal Solid-Organ Transplant Recipients

The number of candidates on the list for kidney transplantation due to end-stage renal disease after a prior nonrenal transplant, particularly liver transplant, is growing significantly.

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