Recent therapeutic advances in metastatic renal cell carcinoma (RCC) have included agents targeted against vascular endothelial growth factor (VEGF).

A pioneering implantable artificial kidney developed jointly by teams of researchers at Cleveland Clinic, the University of California at San Francisco, and the University of Michigan in Ann Arbor is on track to meet project milestones in a pilot and feasibility study funded by the NIH.

The provision of in-hospital dialysis services over the next decade will necessitate a rethinking of the unit infrastructure, coordination of resource allocation, application of newer dialysis techniques, attention to data management and quality targets, and the continuous development of dialysis personnel.

Partial nephrectomy has been the procedure of choice for patients with poor renal function, tumors in solitary kidneys or bilateral renal tumors.

Considering the advancement in the diagnosis and treatment of glomerular disease, we formed a Glomerulonephritis Board (GN Board) at Cleveland Clinic that brings together key medical specialists who can collectively examine specific pathologic findings of complex glomerulonephritis cases, review current treatment approaches, and devise the most effective treatment regimen for salvaging functional renal parenchyma.

The electronic medical record (EMR) has enabled creation of a CKD registry, a database that contains demographic information, clinical parameters, and outcome measurements of more than 41,000 CKD patients who have received medical care within the Cleveland Clinic Health System since January 2005.

There is sufficient evidence to demonstrate that lowering BP to less than 140/90 mm Hg offers cardiovascular and renal protection.

Prostate magnetic resonance (MR) provides high-resolution images of the prostate; seminal vesicles; and nearby pelvic organs and structures, including the bladder and rectum.

Data from 1,000 former kidney donors suggest that normal values of glomerular filtration rate decline with age.

Contentious Issues in Transplantation - A Colloquium October 8-9